3L89
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3IU3
| Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain | 分子名称: | Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ... | 著者 | Du, J, Yang, H, Wang, J, Ding, J. | 登録日 | 2009-08-29 | 公開日 | 2010-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab J.Immunol., 184, 2010
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3INB
| Structure of the measles virus hemagglutinin bound to the CD46 receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Membrane cofactor protein, ... | 著者 | Santiago, C, Celma, M.L, Stehle, T, Casasnovas, J.M. | 登録日 | 2009-08-12 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the measles virus hemagglutinin bound to the CD46 receptor Nat.Struct.Mol.Biol., 17, 2010
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2KMS
| Combined high- and low-resolution techniques reveal compact structure in central portion of factor H despite long inter-modular linkers | 分子名称: | Complement factor H | 著者 | Schmidt, C.Q, Herbert, A.P, Guariento, M, Mertens, H.D.T, Soares, D.C, Uhrin, D, Rowe, A.J, Svergun, D.I, Barlow, P.N. | 登録日 | 2009-08-04 | 公開日 | 2009-11-03 | 最終更新日 | 2020-02-26 | 実験手法 | SOLUTION NMR | 主引用文献 | The Central Portion of Factor H (Modules 10-15) Is Compact and Contains a Structurally Deviant CCP Module J.Mol.Biol., 395, 2010
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3HRZ
| Cobra Venom Factor (CVF) in complex with human factor B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | 登録日 | 2009-06-10 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex Embo J., 28, 2009
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3HS0
| Cobra Venom Factor (CVF) in complex with human factor B | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cobra venom factor, ... | 著者 | Janssen, B.J.C, Gomes, L, Koning, R.I, Svergun, D.I, Koster, A.J, Fritzinger, D.C, Vogel, C.-W, Gros, P. | 登録日 | 2009-06-10 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex Embo J., 28, 2009
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3GAW
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3GOV
| Crystal structure of the catalytic region of human MASP-1 | 分子名称: | GLYCEROL, MASP-1 | 著者 | Harmat, V, Dobo, J, Beinrohr, L, Sebestyen, E, Zavodszky, P, Gal, P. | 登録日 | 2009-03-20 | 公開日 | 2009-06-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity. J.Immunol., 183, 2009
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2WII
| Complement C3b in complex with factor H domains 1-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C3 BETA CHAIN, ... | 著者 | Wu, J, Janssen, B.J.C, Gros, P. | 登録日 | 2009-05-12 | 公開日 | 2009-06-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat. Immunol., 10, 2009
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3GAU
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3GAV
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3ERB
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2W81
| Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H | 分子名称: | COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN | 著者 | Schneider, M.C, Prosser, B.E, Caesar, J.J.E, Kugelberg, E, Li, S, Zhang, Q, Quoraishi, S, Lovett, J.E, Deane, J.E, Sim, R.B, Roversi, P, Johnson, S, Tang, C.M, Lea, S.M. | 登録日 | 2009-01-08 | 公開日 | 2009-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates. Nature, 458, 2009
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2W80
| Structure of a complex between Neisseria meningitidis factor H binding protein and CCPs 6-7 of human complement factor H | 分子名称: | COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN | 著者 | Schneider, M.C, Prosser, B.E, Caesar, J.J.E, Kugelberg, E, Li, S, Zhang, Q, Quoraishi, S, Lovett, J.E, Deane, J.E, Sim, R.B, Roversi, P, Johnson, S, Tang, C.M, Lea, S.M. | 登録日 | 2009-01-08 | 公開日 | 2009-03-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Neisseria Meningitidis Recruits Factor H Using Protein Mimicry of Host Carbohydrates. Nature, 458, 2009
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2RLQ
| NMR structure of CCP modules 2-3 of complement factor H | 分子名称: | Complement factor H | 著者 | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | 登録日 | 2007-07-29 | 公開日 | 2008-02-19 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2RLP
| NMR structure of CCP modules 1-2 of complement factor H | 分子名称: | Complement factor H | 著者 | Hocking, H.G, Herbert, A.P, Pangburn, M.K, Kavanagh, D, Barlow, P.N, Uhrin, D. | 登録日 | 2007-07-28 | 公開日 | 2008-02-19 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the N-terminal region of complement factor H and conformational implications of disease-linked sequence variations. J.Biol.Chem., 283, 2008
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2QY0
| Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts | 分子名称: | Complement C1r subcomponent, GLYCEROL | 著者 | Kardos, J, Harmat, V, Pallo, A, Barabas, O, Szilagyi, K, Graf, L, Naray-Szabo, G, Goto, Y, Zavodszky, P, Gal, P. | 登録日 | 2007-08-13 | 公開日 | 2008-02-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r. Mol.Immunol., 45, 2008
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2PSM
| Crystal structure of Interleukin 15 in complex with Interleukin 15 receptor alpha | 分子名称: | BENZAMIDINE, Interleukin-15, Interleukin-15 receptor alpha chain | 著者 | Olsen, S.K, Murayama, K, Kishishita, S, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Ota, N, Kanagawa, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-07 | 公開日 | 2007-11-06 | 最終更新日 | 2021-08-18 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal Structure of the Interleukin-15{middle dot}Interleukin-15 Receptor {alpha} Complex: INSIGHTS INTO TRANS AND CIS PRESENTATION J.Biol.Chem., 282, 2007
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2QZD
| Fitted structure of SCR4 of DAF into cryoEM density | 分子名称: | Complement decay-accelerating factor | 著者 | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | 登録日 | 2007-08-16 | 公開日 | 2007-10-30 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | Interaction of decay-accelerating factor with coxsackievirus b3. J.Virol., 81, 2007
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2QZH
| SCR2/3 of DAF from the NMR structure 1nwv fitted into a cryoEM reconstruction of CVB3-RD complexed with DAF | 分子名称: | Complement decay-accelerating factor | 著者 | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | 登録日 | 2007-08-16 | 公開日 | 2007-10-30 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | Interaction of decay-accelerating factor with coxsackievirus b3. J.Virol., 81, 2007
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2QZF
| SCR1 of DAF from 1ojv fitted into cryoEM density | 分子名称: | Complement decay-accelerating factor | 著者 | Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G. | 登録日 | 2007-08-16 | 公開日 | 2007-10-30 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (14 Å) | 主引用文献 | Interaction of decay-accelerating factor with coxsackievirus b3. J.Virol., 81, 2007
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2Q7Z
| Solution Structure of the 30 SCR domains of human Complement Receptor 1 | 分子名称: | Complement receptor type 1 | 著者 | Furtado, P.B, Huang, C.Y, Ihyembe, D, Hammond, R.A, Marsh, H.C, Perkins, S.J. | 登録日 | 2007-06-08 | 公開日 | 2007-10-16 | 最終更新日 | 2024-02-21 | 実験手法 | SOLUTION SCATTERING | 主引用文献 | The Partly Folded Back Solution Structure Arrangement of the 30 SCR Domains in Human Complement Receptor Type 1 (CR1) Permits Access to its C3b and C4b Ligands J.Mol.Biol., 375, 2008
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2YRA
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2V8E
| Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, CHLORIDE ION, COMPLEMENT FACTOR H, ... | 著者 | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Tarelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | 登録日 | 2007-08-07 | 公開日 | 2007-10-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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2UWN
| Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand. | 分子名称: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | 著者 | Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M. | 登録日 | 2007-03-22 | 公開日 | 2007-10-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. J.Exp.Med., 204, 2007
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