PDB: 909 件ウェブページステータス検索Chemie searchBIRD

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6DHS	Structure of hnRNP H qRRM1,2 分子名称: Heterogeneous nuclear ribonucleoprotein H 著者 Meagher, J.L, Stuckey, J.A. 登録日 2018-05-21 公開日 2018-09-12 最終更新日 2019-12-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Differential Conformational Dynamics Encoded by the Inter-qRRM linker of hnRNP H. J. Am. Chem. Soc., 2018
6DBP	RNA-recognition motif 1 of human MSI2 分子名称: RNA-binding protein Musashi homolog 2 著者 Goldgur, Y, Kharas, M.G, Minuesa, G. 登録日 2018-05-03 公開日 2019-05-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.603 Å) 主引用文献 Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun, 10, 2019
6XH2	Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6 分子名称: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT 著者 Chavali, S.S, Jenkins, J.L, Wedekind, J.E. 登録日 2020-06-18 公開日 2020-10-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors. J.Biol.Chem., 295, 2020
6XLX	Crystal structure of cancer-associated G301D mutant of U2AF65 bound to AdML splice site 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Maji, D, Jenkins, J.L, Kielkopf, C.L. 登録日 2020-06-29 公開日 2020-10-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
6XLV	Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to AdML splice site 分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit 著者 Maji, D, Jenkins, J.L, Kielkopf, C.L. 登録日 2020-06-29 公開日 2020-10-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. J.Biol.Chem., 295, 2020
7CSX	Crystal structure of the N-terminal tandem RRM domains of RBM45 分子名称: RNA-binding protein 45 著者 Chen, X, Yang, Z, Wang, W, Wang, M. 登録日 2020-08-17 公開日 2021-02-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45. Nucleic Acids Res., 49, 2021
7D1L	complex structure of two RRM domains 分子名称: Embryonic developmental protein tofu-6, Uncharacterized protein 著者 Wang, X, Liao, S, Xu, C. 登録日 2020-09-14 公開日 2021-08-25 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
7DLZ	Crystal Structure of Methyltransferase Ribozyme 分子名称: RNA (45-MER), U1 small nuclear ribonucleoprotein A 著者 Gan, J.H, Gao, Y.Q, Jiang, H.Y, Chen, D.R, Murchie, A.I.H. 登録日 2020-11-30 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.002 Å) 主引用文献 The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences Nat Catal, 4, 2021
5UZG	Crystal structure of Glorund qRRM1 domain 分子名称: AT27789p, GLYCEROL, SULFATE ION 著者 Teramoto, T, Hall, T.M.T. 登録日 2017-02-26 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.541 Å) 主引用文献 The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition. Cell Rep, 19, 2017
5UZM	Crystal structure of Glorund qRRM2 domain 分子名称: AT27789p 著者 Teramoto, T, Hall, T.M.T. 登録日 2017-02-27 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.552 Å) 主引用文献 The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition. Cell Rep, 19, 2017
6HIP	Structure of SPF45 UHM bound to HIV-1 Rev ULM 分子名称: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ... 著者 Pabis, M, Corsini, L, Sattler, M. 登録日 2018-08-30 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors. Nucleic Acids Res., 47, 2019
7DWH	Complex structure of SAM-dependent methyltransferase ribozyme 分子名称: COPPER (II) ION, RNA (45-MER), S-ADENOSYLMETHIONINE, ... 著者 Jiang, H.Y, Gao, Y.Q, Chen, D.R, Murchie, A. 登録日 2021-01-17 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences Nat Catal, 4, 2021
6JVX	Crystal structure of RBM38 in complex with RNA 分子名称: RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3'), RNA-binding protein 38, SULFATE ION 著者 Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. 登録日 2019-04-17 公開日 2020-01-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
7C36	c-Myc DNA binding protein structure 分子名称: RNA-binding motif, single-stranded-interacting protein 1 著者 Aggarwal, P, Bhavesh, N.S. 登録日 2020-05-11 公開日 2021-05-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter. Nucleic Acids Res., 49, 2021
5W0G	Structure of U2AF65 (U2AF2) RRM1 at 1.07 resolution 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ACETATE ION, Splicing factor U2AF 65 kDa subunit, ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2017-05-30 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry, 56, 2017
7EB1	Solution NMR structure of the RRM domain of RNA binding protein RBM3 from homo sapiens 分子名称: RNA-binding protein 3 著者 Boral, S, Roy, S, Basak, A.J, Maiti, S, Lee, W, De, S. 登録日 2021-03-08 公開日 2021-12-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and dynamic studies of the human RNA binding protein RBM3 reveals the molecular basis of its oligomerization and RNA recognition. Febs J., 289, 2022
5WWF	Crystal structure of hnRNPA2B1 in complex with RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2017-01-01 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
7D7V	Crystal Structure of the Domain1 of NAD+ Riboswitch with nicotinamide adenine dinucleotide (NAD+) and U1A protein 分子名称: 17delU1A (58-MER), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Chen, H, Ren, A.M. 登録日 2020-10-06 公開日 2020-11-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding. Nucleic Acids Res., 48, 2020
6JVY	Crystal structure of RBM38 in complex with single-stranded DNA 分子名称: DNA (5'-D(*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*TP*G)-3'), RNA-binding protein 38, SULFATE ION 著者 Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. 登録日 2019-04-17 公開日 2020-01-01 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
5W0H	Structure of U2AF65 (U2AF2) RRM2 at 1.11 Angstrom Resolution 分子名称: Splicing factor U2AF 65 kDa subunit 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2017-05-30 公開日 2018-04-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry, 56, 2017
7D2Y	complex of two RRM domains 分子名称: Embryonic developmental protein tofu-6, RRM2, SULFATE ION 著者 Wang, X, Liao, S, Xu, C. 登録日 2020-09-17 公開日 2021-08-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Molecular basis for PICS-mediated piRNA biogenesis and cell division. Nat Commun, 12, 2021
7CSZ	Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA 分子名称: DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45 著者 Chen, X, Yang, Z, Wang, W, Wang, M. 登録日 2020-08-17 公開日 2021-02-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45. Nucleic Acids Res., 49, 2021
5WWE	Crystal structure of hnRNPA2B1 in complex with RNA 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*GP*AP*CP*UP*AP*GP*A)-3') 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2017-01-01 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018
6KOR	Crystal structure of the RRM domain of SYNCRIP 分子名称: Heterogeneous nuclear ribonucleoprotein Q 著者 Chen, Y, Chan, J, Chen, W, Jobichen, C. 登録日 2019-08-12 公開日 2020-01-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 SYNCRIP, a new player in pri-let-7a processing. Rna, 26, 2020
5WWG	Crystal structure of hnRNPA2B1 in complex with AAGGACUUGC 分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*U)-3') 著者 Wu, B.X, Su, S.C, Ma, J.B. 登録日 2017-01-01 公開日 2018-01-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1. Nat Commun, 9, 2018

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