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2SXL
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SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: SEX-LETHAL PROTEIN
著者Inoue, M, Muto, Y, Sakamoto, H, Kigawa, T, Takio, K, Shimura, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日1997-07-16
公開日1998-07-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal.
J.Mol.Biol., 272, 1997
2RU3
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BU of 2ru3 by Molmil
Solution structure of c.elegans SUP-12 RRM in complex with RNA
分子名称: Protein SUP-12, isoform a, RNA (5'-R(*GP*UP*GP*UP*GP*C)-3')
著者Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y.
登録日2013-11-12
公開日2014-08-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21, 2014
3VAI
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BU of 3vai by Molmil
Structure of U2AF65 variant with BrU3C5 DNA
分子名称: 1,4-DIETHYLENE DIOXIDE, DNA 5'-D(*UP*UP*(BRU)P*UP*CP*UP*U)-3', GLYCEROL, ...
著者Jenkins, J.L, Frato, K.H, Kielkopf, C.L.
登録日2011-12-29
公開日2013-02-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
分子名称: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
著者Kachariya, N, Sattler, M, Keil, P, Strasser, K.
登録日2022-10-04
公開日2022-11-09
最終更新日2024-06-19
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
6SXW
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BU of 6sxw by Molmil
Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
分子名称: SULFATE ION, Zinc finger protein 638
著者Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-09-26
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
To Be Published
6SQQ
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BU of 6sqq by Molmil
Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant in complex with RNA obtained by soaking
分子名称: MAGNESIUM ION, RNA hairpin, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
3V4M
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BU of 3v4m by Molmil
Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution
分子名称: CHLORIDE ION, SODIUM ION, Splicing factor U2AF 65 kDa subunit
著者Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
登録日2011-12-15
公開日2012-06-13
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution
To be published
6SQV
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Structure of the U1A variant A1-98 Y31H/Q36R/R70W
分子名称: SULFATE ION, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SR7
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Structure of the U1A variant A1-98 Y31H/Q36R/K98W
分子名称: SULFATE ION, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-05
公開日2020-05-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SQT
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Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant
分子名称: U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SQN
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Structure of the U1A variant A1-98 Y31H/Q36R/F56W triple mutant co-crystallized with RNA
分子名称: RNA hairpin, U1 small nuclear ribonucleoprotein A
著者Rosenbach, H, Span, I.
登録日2019-09-04
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Expanding crystallization tools for nucleic acid complexes using U1A protein variants.
J.Struct.Biol., 210, 2020
6SNJ
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Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
分子名称: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
著者Campagne, S, Allain, F.H.
登録日2019-08-26
公開日2020-10-28
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
3VAL
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BU of 3val by Molmil
Structure of U2AF65 variant with BrU5C1 DNA
分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*C*UP*UP*UP*(BRU)P*UP*U)-3'), SULFATE ION, ...
著者Jenkins, J.L, Frato, K.H, Kielkopf, C.L.
登録日2011-12-29
公開日2013-02-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.
Nucleic Acids Res., 41, 2013
4C7Q
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BU of 4c7q by Molmil
Solution structure of the Nt. GR-RBP1 RRM domain
分子名称: RNA-BINDING GLYCINE-RICH PROTEIN
著者Kahn, F, Boelens, R, Saqlan, S.M.S, van Ingen, H.
登録日2013-09-24
公開日2013-10-02
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural Basis of Nucleic Acid Binding by Nicotiana Tabacum Glycine-Rich RNA Binding Protein: Implications for its RNA Chaperone Function
Nucleic Acids Res., 42, 2014
4CH0
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RRM domain from C. elegans SUP-12
分子名称: PROTEIN SUP-12, ISOFORM B
著者Amrane, S, Mackereth, C.D.
登録日2013-11-27
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
4ED5
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BU of 4ed5 by Molmil
Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA
分子名称: 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ...
著者Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X.
登録日2012-03-27
公開日2012-05-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
4F02
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Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
分子名称: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
著者Safaee, N, Kozlov, G, Gehring, K.B.
登録日2012-05-03
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4CH1
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BU of 4ch1 by Molmil
RRM domain from C. elegans SUP-12 bound to GGTGTGC DNA
分子名称: GGTGTGC, PROTEIN SUP-12, ISOFORM B
著者Amrane, S, Mackereth, C.D.
登録日2013-11-28
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
4CIO
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BU of 4cio by Molmil
RRM domain from C. elegans SUP-12 bound to GGUGUGC RNA
分子名称: 5'-R(*GP*GP*UP*GP*UP*GP*CP)-3', PROTEIN SUP-12, ISOFORM A
著者Amrane, S, Mackereth, C.D.
登録日2013-12-12
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition
Nat.Commun., 5, 2014
4F26
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Crystal structure of the second RRM domain of human PABPC1 a pH 9.0
分子名称: Polyadenylate-binding protein 1
著者Kozlov, G, Safaee, N, Gehring, K.
登録日2012-05-07
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F25
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Crystal structure of the second RRM domain of human PABPC1 at pH 6.0
分子名称: Polyadenylate-binding protein 1
著者Kozlov, G, Safaee, N, Gehring, K.
登録日2012-05-07
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4EGL
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BU of 4egl by Molmil
Crystal structure of two tandem RNA recognition motifs of Human antigen R
分子名称: ELAV-like protein 1, GLYCEROL, SULFATE ION
著者Wang, H, Zeng, F, Liu, H, Teng, M, Li, X.
登録日2012-03-31
公開日2012-05-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of two tandem RNA recognition motifs of Human antigen R
To be Published
1PGZ
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Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(6-MI)G); A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6-MI)
分子名称: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*GP*(6MI)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Moore, S.A, Shamoo, Y.
登録日2003-05-28
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.Biol.Chem., 278, 2003
3EGN
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BU of 3egn by Molmil
C-terminal RNA Recognition Motif of the U11/U12 65K Protein
分子名称: RNA-binding protein 40
著者Netter, C, Wahl, M.C.
登録日2008-09-11
公開日2009-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional stabilization of an RNA recognition motif by a noncanonical N-terminal expansion
Rna, 15, 2009
7SN6
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U2AF65 UHM BOUND TO SF3B155 ULM5
分子名称: ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit
著者Loerch, S, Jenkins, J.L, Kielkopf, C.L.
登録日2021-10-27
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
J.Biol.Chem., 298, 2022

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