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5VET
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PHOSPHOLIPASE A2, RE-REFINEMENT OF THE PDB STRUCTURE 1JQ8 WITHOUT THE PUTATIVE COMPLEXED OLIGOPEPTIDE
分子名称: Phospholipase A2 VRV-PL-VIIIa
著者Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
登録日2017-04-05
公開日2018-06-20
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
5VFM
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Crystal structure of BnSP-7 from Bothrops pauloensis complexed with p-coumaric acid
分子名称: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, 4'-HYDROXYCINNAMIC ACID, Basic phospholipase A2 homolog BnSP-7, ...
著者De Lima, L.F.G, Fontes, M.R.M.
登録日2017-04-08
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.058 Å)
主引用文献Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
Biochimie, 142, 2017
5VFJ
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Crystal structure of BnSP-7 from bothrops pauloensis complexed with caffeic acid
分子名称: Basic phospholipase A2 homolog BnSP-7, CAFFEIC ACID, SULFATE ION
著者De Lima, L.F.G, Fontes, M.R.M.
登録日2017-04-07
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.084 Å)
主引用文献Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins.
Biochimie, 142, 2017
5WZT
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Crystal structure of human secreted phospholipase A2 group IIE with Compound 14
分子名称: 2-[1-[(3-bromophenyl)methyl]-2-methyl-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
5WZM
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Crystal structure of human secreted phospholipase A2 group IIE
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
5WZS
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Crystal structure of human secreted phospholipase A2 group IIE with Compound 8
分子名称: 2-[2-methyl-1-(naphthalen-1-ylmethyl)-3-oxamoyl-indol-4-yl]oxyethanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
5WZV
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Crystal structure of human secreted phospholipase A2 group IIE with Me-indoxam
分子名称: 2-[2-methyl-3-oxamoyl-1-[(2-phenylphenyl)methyl]indol-4-yl]oxyethanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
5WZO
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Crystal structure of human secreted phospholipase A2 group IIE, crystallized with calcium
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
5WZU
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Crystal structure of human secreted phospholipase A2 group IIE with Compound 24
分子名称: 2-[2-methyl-3-oxamoyl-1-[[2-(trifluoromethyl)phenyl]methyl]indol-4-yl]oxyethanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
5WZW
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Crystal structure of human secreted phospholipase A2 group IIE with LY311727
分子名称: (3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid, CALCIUM ION, CHLORIDE ION, ...
著者Hou, S, Xu, J, Xu, T, Liu, J.
登録日2017-01-18
公開日2018-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE
Sci Rep, 7, 2017
3FO7
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Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
分子名称: INDOMETHACIN, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Prem Kumar, R, Sharma, S, Kaur, P, Singh, T.P.
登録日2008-12-29
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site
To be Published
1J1A
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PANCREATIC SECRETORY PHOSPHOLIPASE A2 (IIa) WITH ANTI-INFLAMMATORY ACTIVITY
分子名称: (S)-5-(4-BENZYLOXY-PHENYL)-4-(7-PHENYL-HEPTANOYLAMINO)-PENTANOIC ACID, CALCIUM ION, Phospholipase A2
著者Hansford, K.A, Reid, R.C, Clark, C.I, Tyndall, J.D.A, Whitehouse, M.W, Guthrie, T, McGeary, R.P, Schafer, K, Martin, J.L, Fairlie, D.P.
登録日2002-12-03
公開日2003-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献D-Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity
Chembiochem, 4, 2003
1IJL
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Crystal structure of acidic phospholipase A2 from deinagkistrodon acutus
分子名称: CALCIUM ION, PHOSPHOLIPASE A2, ZINC ION
著者Gu, L, Zhang, H, Song, S, Zhou, Y, Lin, Z.
登録日2001-04-27
公開日2001-12-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of an acidic phospholipase A2 from the venom of Deinagkistrodon acutus.
Acta Crystallogr.,Sect.D, 58, 2002
3FVI
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Crystal Structure of Complex of Phospholipase A2 with Octyl Sulfates
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Pan, Y.H.
登録日2009-01-15
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2.
Biochim.Biophys.Acta, 1804, 2010
1IRB
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CARBOXYLIC ESTER HYDROLASE
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Sundaralingam, M.
登録日1997-08-13
公開日1997-12-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
Biochemistry, 35, 1996
1JQ9
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Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Phe-Leu-Ser-Tyr-Lys at 1.8 resolution
分子名称: ACETIC ACID, Peptide inhibitor, Phospholipase A2
著者Chandra, V, Jasti, J, Kaur, P, Dey, S, Betzel, C, Singh, T.P.
登録日2001-08-04
公開日2002-11-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
1GP7
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Acidic Phospholipase A2 from venom of Ophiophagus Hannah
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Zhang, H, Lin, Z.
登録日2001-10-30
公開日2002-10-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a Cardiotoxic Phospholipase A(2) from Ophiophagus Hannah with the "Pancreatic Loop"
J.Struct.Biol., 138, 2002
3G8F
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Crystal structure of the complex formed between a group II phospholipase A2 and designed peptide inhibitor carbobenzoxy-dehydro-val-ala-arg-ser at 1.2 A resolution
分子名称: PHQ VAL ALA ARG SER peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION
著者Singh, N, Kaur, P, Prem Kumar, R, Somvanshi, R.K, Perbandt, M, Betzel, C, Dey, S, Sharma, S, Singh, T.P.
登録日2009-02-12
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal Structure of the Complex Formed between a Group II Phospholipase A2 and Designed Peptide Inhibitor Carbobenzoxy-Dehydro-Val-Ala-Arg-Ser at 1.2 A Resolution
To be Published
3HZD
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Crystal structure of bothropstoxin-I (BthTX-I), a PLA2 homologue from Bothrops jararacussu venom
分子名称: LITHIUM ION, Phospholipase A2 homolog bothropstoxin-1
著者Silva, M.C.O, Marchi-Salvador, D.P, Fernandes, C.A.H, Soares, A.M, Fontes, M.R.M.
登録日2009-06-23
公開日2009-07-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.
J.Struct.Biol., 171, 2010
3I3H
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Crystal structure of Bothropstoxin-I crystallized at 291K
分子名称: Phospholipase A2 homolog bothropstoxin-1
著者Salvador, G.H.M, Marchi-Salvador, D.P, Soares, A.M, Fontes, M.R.M.
登録日2009-06-30
公開日2010-08-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural Studies with a BthTX-I a Lys49 PLA2 from Bothrops jararacussu Snake Venom Crystallized at Different Temperatures
To be Published
3FVJ
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Crystal structure of phospholipase A2 1B crystallized in the presence of octyl sulfate
分子名称: CALCIUM ION, CHLORIDE ION, Phospholipase A2, ...
著者Pan, Y.H.
登録日2009-01-15
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a premicellar complex of alkyl sulfates with the interfacial binding surfaces of four subunits of phospholipase A2.
Biochim.Biophys.Acta, 1804, 2010
3G8H
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Crystal structure of phospholipase A2 ammodytoxin C from vipera ammodytes ammodytes
分子名称: Phospholipase A2, ammodytoxin C, SULFATE ION
著者Saul, F.A, Faure, G.
登録日2009-02-12
公開日2009-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity
J.Struct.Biol., 169, 2010
3GCI
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Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal Amyloid Beta Heptapeptide at 2 A Resolution
分子名称: CALCIUM ION, Heptapeptide from Amyloid beta A4 protein, Phospholipase A2 isoform 3
著者Mirza, Z, Vikram, G, Singh, N, Sinha, M, Bhushan, A, Sharma, S, Srinivasan, A, Kaur, P, Singh, T.P.
登録日2009-02-22
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal Structure of the Complex Formed Between a New Isoform of Phospholipase A2 with C-terminal Amyloid Beta Heptapeptide at 2 A Resolution
To be Published
1JIA
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STRUCTURE OF A BASIC PHOSPHOLIPASE A2 FROM AGKISTRODON HALYS PALLAS AT 2.13A RESOLUTION
分子名称: CALCIUM ION, PHOSPHOLIPASE A2
著者Zhao, K, Lin, Z.
登録日1997-06-09
公開日1998-06-10
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure of a basic phospholipase A2 from Agkistrodon halys Pallas at 2.13 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
3G8G
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Crystal structure of phospholipase A2 ammodytoxin A from vipera ammodytes ammodytes
分子名称: Phospholipase A2, ammodytoxin A, SULFATE ION
著者Saul, F.A, Faure, G.
登録日2009-02-12
公開日2009-12-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity
J.Struct.Biol., 169, 2010

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件を2024-08-07に公開中

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