3HZD
Crystal structure of bothropstoxin-I (BthTX-I), a PLA2 homologue from Bothrops jararacussu venom
Summary for 3HZD
Entry DOI | 10.2210/pdb3hzd/pdb |
Related | 1Y4L 2Q2J 3CXI 3CYL 3HZW 3I03 |
Descriptor | Phospholipase A2 homolog bothropstoxin-1, LITHIUM ION (3 entities in total) |
Functional Keywords | bothrops, snake venom, phospholipase a2, lys49-pla2s, myotoxicity, antibiotic, antimicrobial, disulfide bond, myotoxin, secreted, toxin |
Biological source | Bothrops jararacussu (snake) |
Cellular location | Secreted: Q90249 |
Total number of polymer chains | 2 |
Total formula weight | 27513.21 |
Authors | Silva, M.C.O.,Marchi-Salvador, D.P.,Fernandes, C.A.H.,Soares, A.M.,Fontes, M.R.M. (deposition date: 2009-06-23, release date: 2009-07-07, Last modification date: 2024-04-03) |
Primary citation | Fernandes, C.A.,Marchi-Salvador, D.P.,Salvador, G.M.,Silva, M.C.,Costa, T.R.,Soares, A.M.,Fontes, M.R. Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171:31-43, 2010 Cited by PubMed: 20371382DOI: 10.1016/j.jsb.2010.03.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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