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6TME
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Monomeric LRX8 in complex with RALF4.
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(3-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Moussu, S, Caroline, C, Santos-Fernandez, G, Wehrle, S, Grossniklaus, U, Santiago, J.
登録日2019-12-04
公開日2020-03-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structural basis for recognition of RALF peptides by LRX proteins during pollen tube growth.
Proc.Natl.Acad.Sci.USA, 117, 2020
7WR3
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BU of 7wr3 by Molmil
Crystal structure of MBP-fused OspC3 in complex with calmodulin
分子名称: Calmodulin-1, MBP-fused OspC3, NICOTINAMIDE, ...
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
8T6L
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Cryo-EM structure of rat cardiac sodium channel NaV1.5 with batrachotoxin analog BTX-B
分子名称: (1R)-1-[(5aR,7aR,9R,11aS,11bS,12R,13aR)-9,12-dihydroxy-2,11a-dimethyl-1,2,3,4,7a,8,9,10,11,11a,12,13-dodecahydro-7H-9,11b-epoxy-13a,5a-prop[1]enophenanthro[2,1-f][1,4]oxazepin-14-yl]ethyl benzoate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ...
著者Tonggu, L, Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2023-06-16
公開日2024-03-06
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin.
Nat Commun, 15, 2024
2INV
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BU of 2inv by Molmil
Crystal structure of Inulin fructotransferase in the presence of di-fructose
分子名称: Inulin fructotransferase, PHOSPHONATE, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose
著者Rhee, S, Jung, W.S.
登録日2006-10-09
公開日2006-12-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and functional insights into intramolecular fructosyl transfer by inulin fructotransferase
J.Biol.Chem., 282, 2007
7CA5
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BU of 7ca5 by Molmil
Cryo-EM structure of human GABA(B) receptor in apo state
分子名称: Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2
著者Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y.
登録日2020-06-08
公開日2020-11-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structural Basis for Activation of the Heterodimeric GABA B Receptor.
J.Mol.Biol., 432, 2020
7WR5
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BU of 7wr5 by Molmil
Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+
分子名称: Calmodulin-1, Caspase-4, OspC3, ...
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
7LXC
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BU of 7lxc by Molmil
Structure and Interactions of DED1 of human cFLIP
分子名称: DED1ch
著者Panaitiu, A.E, Basiashvili, T, Mierke, D.F, Pellegrini, M.
登録日2021-03-03
公開日2021-12-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An engineered construct of cFLIP provides insight into DED1 structure and interactions.
Structure, 30, 2022
6NPA
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BU of 6npa by Molmil
X-ray crystal structure of TmpB, (R)-1-hydroxy-2-trimethylaminoethylphosphonate oxygenase, with (R)-1-hydroxy-2-trimethylaminoethylphosphonate
分子名称: (2R)-2-hydroxy-N,N,N-trimethyl-2-phosphonoethan-1-aminium, FE (II) ION, FE (III) ION, ...
著者Rajakovich, L.J, Mitchell, A.J, Boal, A.K.
登録日2019-01-17
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases.
Biochemistry, 58, 2019
6MU1
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BU of 6mu1 by Molmil
Structure of full-length IP3R1 channel bound with Adenophostin A
分子名称: Adenophostin A, Inositol 1,4,5-trisphosphate receptor type 1
著者Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L.
登録日2018-10-22
公開日2018-12-05
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Cell Res., 28, 2018
7WSX
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BU of 7wsx by Molmil
Class III hybrid cluster protein (HCP) C67Y variant from Methanothermobacter marburgensis
分子名称: FE-S-O HYBRID CLUSTER, Hydroxylamine reductase
著者Fujishiro, T.
登録日2022-02-02
公開日2023-02-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Class III hybrid cluster protein homodimeric architecture shows evolutionary relationship with Ni, Fe-carbon monoxide dehydrogenases.
Nat Commun, 14, 2023
5KRS
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BU of 5krs by Molmil
HIV-1 Integrase Catalytic Core Domain in Complex with an Allosteric Inhibitor, 3-(1H-pyrrol-1-yl)-2-thiophenecarboxylic acid
分子名称: 3-pyrrol-1-ylthiophene-2-carboxylic acid, DIMETHYL SULFOXIDE, Integrase
著者Patel, D, Bauman, J.D, Arnold, E.
登録日2016-07-07
公開日2016-09-28
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain.
J.Biol.Chem., 291, 2016
6N5W
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BU of 6n5w by Molmil
Crystal structure of the Ca2+/CaM complex with independent peptides of Kv7.4 (KCNQ4) A & B domains
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 4
著者Taylor, A.B, Archer, C.R, Shapiro, M.S.
登録日2018-11-22
公開日2019-03-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+channels.
J. Biol. Chem., 294, 2019
1KYT
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BU of 1kyt by Molmil
Crystal Structure of Thermoplasma acidophilum 0175 (APC014)
分子名称: CALCIUM ION, hypothetical protein TA0175
著者Kim, Y, Joachimiak, A, Edwards, A, Xu, X, Pennycooke, M, Gu, J, Cheung, F, Christendat, D, Midwest Center for Structural Genomics (MCSG)
登録日2002-02-05
公開日2003-01-21
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Thermoplasma acidophilum 0175 (APC014)
To be published
6BUT
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BU of 6but by Molmil
Solution structure of full-length apo mammalian calmodulin bound to the IQ motif of the human voltage-gated sodium channel NaV1.2
分子名称: Calmodulin-1, Sodium channel protein type 2 subunit alpha
著者Mahling, R, Kilpatrick, A.M, Shea, M.A.
登録日2017-12-11
公開日2019-06-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Na V 1.2 EFL domain allosterically enhances Ca 2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.
Structure, 2021
1L3N
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BU of 1l3n by Molmil
The Solution Structure of Reduced Dimeric Copper Zinc SOD: the Structural Effects of Dimerization
分子名称: COPPER (I) ION, ZINC ION, superoxide dismutase [Cu-Zn]
著者Banci, L, Bertini, I, Cramaro, F, Del Conte, R, Viezzoli, M.S.
登録日2002-02-28
公開日2002-05-08
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献The solution structure of reduced dimeric copper zinc superoxide dismutase. The structural effects of dimerization
Eur.J.Biochem., 269, 2002
6C6Q
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BU of 6c6q by Molmil
Crystal Structure of the Murine Norovirus VP1 P Domain in complex with the CD300lf Receptor
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CMRF35-like molecule 1, ...
著者Nelson, C.A, Fremont, D.H.
登録日2018-01-19
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1L1N
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BU of 1l1n by Molmil
POLIOVIRUS 3C PROTEINASE
分子名称: Genome polyprotein: Picornain 3C
著者Mosimann, S.C, Chernaia, M.M, Sia, S, Plotch, S, James, M.N.G.
登録日2002-02-19
公開日2002-04-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Refined X-ray crystallographic structure of the poliovirus 3C gene product.
J.Mol.Biol., 273, 1997
8HJT
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BU of 8hjt by Molmil
Crystal Structure of Intracellular B30.2 Domain of VpBTN3 and VpBTN2 in Complex with HMBPP
分子名称: (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Butyrophylin 3, ...
著者Yang, Y.Y, Shen, P.P, Li, X, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T.
登録日2022-11-23
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
6C9D
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BU of 6c9d by Molmil
Crystal structure of KA1-autoinhibited MARK1 kinase
分子名称: Serine/threonine-protein kinase MARK1,Serine/threonine-protein kinase MARK1
著者Emptage, R.P, Marmorstein, R.
登録日2018-01-26
公開日2018-07-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain.
Structure, 26, 2018
5M54
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BU of 5m54 by Molmil
Mechanism of microtubule minus-end recognition and protection by CAMSAP proteins
分子名称: Calmodulin-regulated spectrin-associated protein 1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Akhmanova, A, Moores, C.A, Baldus, M, Steinmetz, M.O, Topf, M, Roberts, A.J, Grant, B.J, Scarabelli, G, Joseph, A.-J, van Hooff, J.J.E, Houben, K, Hua, S, Luo, Y, Stangier, M.M, Jiang, K, Atherton, J.
登録日2016-10-20
公開日2017-10-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nat. Struct. Mol. Biol., 24, 2017
6TO6
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BU of 6to6 by Molmil
Solution structure of the modulator of repression (MOR) of the temperate bacteriophage TP901-1 from Lactococcus lactis
分子名称: MOR
著者Rasmussen, K.K, Blackledge, M, Herrmann, T, Lo Leggio, L, Jensen, M.R.
登録日2019-12-11
公開日2020-08-19
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.
Proc.Natl.Acad.Sci.USA, 117, 2020
2KS0
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BU of 2ks0 by Molmil
Solution NMR structure of the Q251Q8_DESHY(21-82) protein from Desulfitobacterium Hafniense, Northeast Structural Genomics Consortium Target DhR8C
分子名称: Uncharacterized protein
著者Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2009-12-23
公開日2010-01-12
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Combining NMR and EPR methods for homodimer protein structure determination.
J.Am.Chem.Soc., 132, 2010
6NPB
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BU of 6npb by Molmil
X-ray crystal structure of TmpA, 2-trimethylaminoethylphosphonate hydroxylase, with Fe and 2OG
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, SULFATE ION, ...
著者Rajakovich, L.J, Mitchell, A.J, Boal, A.K.
登録日2019-01-17
公開日2019-03-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases.
Biochemistry, 58, 2019
7Y7T
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BU of 7y7t by Molmil
QDE-1 in complex with 12nt DNA template, ATP and 3'-dGTP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*AP*G*AP*GP*AP*CP*CP*TP*TP*TP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, ...
著者Cui, R.X, Gan, J.H, Ma, J.B.
登録日2022-06-22
公開日2022-09-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Nucleic Acids Res., 50, 2022
8FVJ
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BU of 8fvj by Molmil
Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5
分子名称: Core-binding factor subunit beta, Cullin-5, Elongin-B, ...
著者Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S.
登録日2023-01-19
公開日2023-09-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023

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