PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

---

6DXA	Crystal structure of chalcone synthase from Pinus sylvestris 分子名称: Chalcone synthase 著者 Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K. 登録日 2018-06-28 公開日 2018-10-17 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. J. Biol. Chem., 293, 2018
6QJK	Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P43 分子名称: Disks large homolog 4, GLYCEROL, SULFATE ION 著者 Camara-Artigas, A. 登録日 2019-01-24 公開日 2019-04-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.046 Å) 主引用文献 Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95. Acta Crystallogr D Struct Biol, 75, 2019
6QFF	Crystal Structure of Human Kallikrein 6 in complex with GSK144 分子名称: 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, Kallikrein-6 著者 Thorpe, J.H. 登録日 2019-01-10 公開日 2019-05-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome. Acta Crystallogr.,Sect.F, 75, 2019
6DPX	X-ray crystal structure of AmpC beta-lactamase with inhibitor 分子名称: (3-{[(3-chloro-2-hydroxyphenyl)sulfonyl]amino}phenyl)acetic acid, Beta-lactamase 著者 Singh, I. 登録日 2018-06-09 公開日 2018-07-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ultra-large library docking for discovering new chemotypes. Nature, 566, 2019
6QLM	Cathepsin-K in complex with MIV-701 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Cathepsin K, GLYCEROL, ... 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
6QM0	Cathepsin-K in complex with amino-oxaazabicyclo[3.3.0]octanyl containing inhibitor 分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, Cathepsin K, ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{R})-6-azanyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-3-fluoranyl-4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
6D9B	Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex with UDP-glucose (open, oxidized) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, ISOPROPYL ALCOHOL, SODIUM ION, ... 著者 Wangkanont, K, Kiessling, L.L, Forest, K.T. 登録日 2018-04-28 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate recognition by FAD in UDP-galactopyranose mutase To be published
6DXF	Crystal structure of chalcone synthase from Selaginella moellendorffii - hydrogen peroxide treated 分子名称: Chalcone synthase 著者 Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K. 登録日 2018-06-28 公開日 2018-10-17 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. J. Biol. Chem., 293, 2018
6QV1	Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM1 分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ... 著者 Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. 登録日 2019-03-01 公開日 2019-05-29 最終更新日 2019-06-05 実験手法 X-RAY DIFFRACTION (3.48 Å) 主引用文献 The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
6QV2	Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM#2 分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ... 著者 Hutter, C.A.J, Huerlimann, L.M, Zimmermann, I, Egloff, P, Seeger, M.A. 登録日 2019-03-01 公開日 2019-05-29 最終更新日 2019-06-05 実験手法 X-RAY DIFFRACTION (4.23 Å) 主引用文献 The extracellular gate shapes the energy profile of an ABC exporter. Nat Commun, 10, 2019
6D3Y	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: GLYCEROL, Plasminogen, SULFATE ION, ... 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
6D46	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Rickettsia typhi str. Wilmington 分子名称: Beta sliding clamp, CHLORIDE ION, TETRAETHYLENE GLYCOL 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-04-17 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Rickettsia typhi str. Wilmington To Be Published
6D5A	Crystal structure of L,D-transpeptidase 5 from Mycobacterium tuberculosis in apo form 分子名称: L,D-transpeptidase 5, TETRAETHYLENE GLYCOL 著者 Libreros, G.A, Dias, M.V. 登録日 2018-04-19 公開日 2019-02-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.622 Å) 主引用文献 Structural Basis for the Interaction and Processing of beta-Lactam Antibiotics by l,d-Transpeptidase 3 (LdtMt3) from Mycobacterium tuberculosis. ACS Infect Dis, 5, 2019
6QLX	Cathepsin-K in complex with fluoro-oxa-azabicyclo[3.3.0]octanyl containing inhibitor 分子名称: Cathepsin K, ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{S},6~{a}~{S})-6-fluoranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-thiophen-2-yl-benzamide 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
6DEG	Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 分子名称: Beta sliding clamp 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2018-05-11 公開日 2018-05-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of a DNA polymerase III subunit beta DnaN sliding clamp from Bartonella birtlesii LL-WM9 To Be Published
6DEX	Structure of Eremothecium gossypii Shu1:Shu2 complex 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MAGNESIUM ION, Suppressor of hydroxyurea sensitivity protein 1, ... 著者 Singh, N, Corbett, K.D. 登録日 2018-05-13 公開日 2018-05-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Eremothecium gossypii Shu1:Shu2 complex To Be Published
5DQF	Horse Serum Albumin (ESA) in complex with Cetirizine 分子名称: (2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, (2-{4-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid, CHLORIDE ION, ... 著者 Handing, K.B, Shabalin, I.G, Majorek, K.A, Chruszcz, M, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2015-09-14 公開日 2015-12-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of equine serum albumin in complex with cetirizine reveals a novel drug binding site. Mol.Immunol., 71, 2016
6D9C	Crystal structure of Corynebacterium diphtheriae UDP-galactopyranose mutase in complex with UDP-glucose (open, reduced) 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SODIUM ION, UDP-galactopyranose mutase, ... 著者 Wangkanont, K, Kiessling, L.L, Forest, K.T. 登録日 2018-04-28 公開日 2019-05-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Substrate recognition by FAD in UDP-galactopyranose mutase To be published
6DNT	UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with UDP-N-acetylmuramic acid 分子名称: (2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid, 1,2-ETHANEDIOL, NAD-dependent epimerase/dehydratase, ... 著者 Carbone, V, Schofield, L.R, Sang, C, Sutherland-Smith, A.J, Ronimus, R.S. 登録日 2018-06-07 公開日 2018-10-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural determination of archaeal UDP-N-acetylglucosamine 4-epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP-N-acetylmuramic acid. Proteins, 86, 2018
6DPZ	X-ray crystal structure of AmpC beta-lactamase with inhibitor 分子名称: (1R,2S)-2-{[(pyrrolidin-1-yl)sulfonyl]amino}cyclooctane-1-carboxylic acid, Beta-lactamase 著者 Singh, I. 登録日 2018-06-09 公開日 2018-07-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Ultra-large library docking for discovering new chemotypes. Nature, 566, 2019
6QZJ	Crystal structure of human Aquaporin 7 at 2.2 A resolution 分子名称: Aquaporin-7, GLYCEROL, PHOSPHATE ION 著者 de Mare, S.W.-H, Venskutonyte, R, Eltschkner, S, Lindkvist-Petersson, K. 登録日 2019-03-11 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7. Structure, 28, 2020
6DRU	Xylosidase from Aspergillus niger 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Glycosyl hydrolases family 31 family protein, ... 著者 Cao, H, Xu, W, Betancourt, M, Walton, J.D, Brumm, P, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2018-06-13 公開日 2018-08-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of alpha-Xylosidase fromAspergillus nigerin Complex with a Hydrolyzed Xyloglucan Product and New Insights in Accurately Predicting Substrate Specificities of GH31 Family Glycosidases. Acs Sustain Chem Eng, 8, 2020
6QLW	Cathepsin-K in complex with MIV-710 分子名称: CHLORIDE ION, Cathepsin K, SODIUM ION, ... 著者 Derbyshire, D.J. 登録日 2019-02-01 公開日 2020-02-19 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Successful development of 3-oxohexahydrofuropyrrole amino acid amides as inhibitors of Cathepsin-K. To Be Published
6QPL	Crystal structure of Spindlin1 in complex with the inhibitor MS31 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Johansson, C, Krojer, T, Xiong, Y, Jin, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. 登録日 2019-02-14 公開日 2019-07-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1). J.Med.Chem., 62, 2019
6D3X	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: Plasminogen, Trypsin inhibitor 1 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019

<52535455565758596061626364656667>