6DPX
X-ray crystal structure of AmpC beta-lactamase with inhibitor
Summary for 6DPX
| Entry DOI | 10.2210/pdb6dpx/pdb |
| Descriptor | Beta-lactamase, (3-{[(3-chloro-2-hydroxyphenyl)sulfonyl]amino}phenyl)acetic acid (3 entities in total) |
| Functional Keywords | ampc beta-lacatamase, inhibitor complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Escherichia coli (strain K12) |
| Total number of polymer chains | 2 |
| Total formula weight | 79859.38 |
| Authors | Singh, I. (deposition date: 2018-06-09, release date: 2018-07-04, Last modification date: 2023-10-11) |
| Primary citation | Lyu, J.,Wang, S.,Balius, T.E.,Singh, I.,Levit, A.,Moroz, Y.S.,O'Meara, M.J.,Che, T.,Algaa, E.,Tolmachova, K.,Tolmachev, A.A.,Shoichet, B.K.,Roth, B.L.,Irwin, J.J. Ultra-large library docking for discovering new chemotypes. Nature, 566:224-229, 2019 Cited by PubMed: 30728502DOI: 10.1038/s41586-019-0917-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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