PDB: 9904 件ウェブページステータス検索Chemie searchBIRD

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4Q97	IgNAR antibody domain C1 分子名称: Novel antigen receptor 著者 Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. 登録日 2014-04-29 公開日 2014-07-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins. Proc.Natl.Acad.Sci.USA, 111, 2014
6S2I	Anti-tumor antibody 14F7-derived scFv in complex with NeuGc Gm3 分子名称: N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, scFv C1 著者 Bjerregaard-Andersen, K, Heggelund, J.E, Krengel, U. 登録日 2019-06-20 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.285 Å) 主引用文献 Key role of a structural water molecule for the specificity of 14F7-An antitumor antibody targeting the NeuGc GM3 ganglioside. Glycobiology, 31, 2021
6WX1	Antigen Binding Fragment of OKT9 分子名称: GLYCEROL, OKT9 Fab Heavy Chain, OKT9 Fab Light Chain 著者 Rodriguez, J.A, Helguera, G, Sawaya, M, Cascio, D, Collazo, M, Flores, M, Zink, S, Ferrero, S, Payes, C, Fuentes, D, Short, C. 登録日 2020-05-09 公開日 2021-05-26 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J.Virol., 95, 2021
3GBN	Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin 分子名称: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ekiert, D.C, Elsliger, M.A, Wilson, I.A. 登録日 2009-02-20 公開日 2009-03-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Antibody recognition of a highly conserved influenza virus epitope. Science, 324, 2009
3IXY	The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53 分子名称: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ... 著者 Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H. 登録日 2009-02-26 公開日 2009-10-27 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (23 Å) 主引用文献 Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody Embo J., 28, 2009
5E2T	Crystal structure of anti-TAU antibody AT8 FAB 分子名称: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, CALCIUM ION 著者 Malia, T, Teplyakov, A. 登録日 2015-10-01 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8. Proteins, 84, 2016
3IXX	The pseudo-atomic structure of West Nile immature virus in complex with Fab fragments of the anti-fusion loop antibody E53 分子名称: E53 Fab Fragment (chain H), E53 Fab Fragment (chain L), Envelope protein E, ... 著者 Cherrier, M.V, Kaufmann, B, Nybakken, G.E, Lok, S.M, Warren, J.T, Nelson, C.A, Kostyuchenko, V.A, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Diamond, M.S, Rossmann, M.G, Fremont, D.H. 登録日 2009-02-26 公開日 2009-10-27 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody Embo J., 28, 2009
6UYE	EBOV GPdMuc Makona bound to rEBOV-548 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody rEBOV-548 Fab, ... 著者 Murin, C.D, Ward, A.B. 登録日 2019-11-13 公開日 2020-03-11 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity, 52, 2020
4YPG	Structural Insights Into the Neutralization Properties of a Human Anti-Interferon Monoclonal Antibody 分子名称: Interferon alpha-2, NICKEL (II) ION, Sifalimumab heavy chain, ... 著者 Oganesyan, V, Dall'Acqua, W.F. 登録日 2015-03-12 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab. J.Biol.Chem., 290, 2015
4M3K	Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis 分子名称: Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S 著者 Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. 登録日 2013-08-06 公開日 2014-08-06 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To be Published
5GZR	Zika virus E protein complexed with a neutralizing antibody Z23-Fab 分子名称: Z23 Fab heavy chain, Z23 Fab light chain, structural protein E, ... 著者 Gao, G.G, Shi, Y, Peng, R, Liu, S. 登録日 2016-10-01 公開日 2016-11-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (9.4 Å) 主引用文献 Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
6LUN	NN2101 Antibody Fab fragment 分子名称: NN2101 著者 Kim, H.N, Seo, M.D, Park, S.K. 登録日 2020-01-30 公開日 2021-02-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Development and characterization of a fully human antibody targeting SCF/c-kit signaling. Int.J.Biol.Macromol., 159, 2020
7PKL	Mechanistic understanding of antibody masking with anti-idiotypic antibody fragments 分子名称: SULFATE ION, trastuzumab Heavy Chain, trastuzumab Light Chain VHH fusion 著者 Hargreaves, D. 登録日 2021-08-25 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Mechanistic insights into the rational design of masked antibodies. Mabs, 14
7QF1	Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2.6264 heavy chain, CV2.6264 light chain, ... 著者 Fernandez, I, Pederzoli, R, Rey, F.A. 登録日 2021-12-03 公開日 2022-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
7QF0	Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.2325 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CV2.2325 heavy chain, ... 著者 Fernandez, I, Pederzoli, R, Rey, F.A. 登録日 2021-12-03 公開日 2022-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
7QEZ	Crystal structure of the SARS-CoV-2 RBD in complex with the ultrapotent antibody CV2.1169 and CR3022 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 heavy chain, CR3022 light chain, ... 著者 Fernandez, I, Rey, F.A. 登録日 2021-12-03 公開日 2022-05-18 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2. J.Exp.Med., 219, 2022
7T2P	The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Berndsen, Z.T, Ward, A.B. 登録日 2021-12-06 公開日 2022-10-19 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nat Commun, 13, 2022
7T4G	The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Berndsen, Z.T, Ward, A.B. 登録日 2021-12-09 公開日 2022-10-19 最終更新日 2023-07-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nat Commun, 13, 2022
7CM4	Crystal Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody CT-P59 分子名称: 1,2-ETHANEDIOL, IgG heavy chain, IgG light chain, ... 著者 Kim, Y.G, Jeong, J.H, Bae, J.S, Lee, J. 登録日 2020-07-24 公開日 2021-01-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein. Nat Commun, 12, 2021
4HWE	Crystal structure of ectodomain 3 of the IL-13 receptor alpha1 in complex with a human neutralizing monoclonal antibody fragment 分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ... 著者 Xu, Y. 登録日 2012-11-07 公開日 2013-02-27 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Crystal structure of ectodomain 3 of the IL-13 receptor alpha1 in complex with a human neutralizing monoclonal antibody fragment Biochem.J., 451, 2013
4HWB	Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Fab heavy chain, Fab light chain, ... 著者 Xu, Y. 登録日 2012-11-07 公開日 2013-02-27 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment Biochem.J., 451, 2013
7T86	Crystal Structure of Fab CR5133 / Phospho-SD Peptide Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab CR5133 Heavy Chain, Antibody Fab CR5133 Light Chain, ... 著者 Luo, J, Malia, T.J, Buckley, P.T. 登録日 2021-12-15 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Cell Host Microbe, 31, 2023
5VOB	Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Malito, E, Chandramouli, S. 登録日 2017-05-02 公開日 2017-07-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.02 Å) 主引用文献 Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2, 2017
5VOC	Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 - Low resolution dataset for initial phasing by SAD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... 著者 Malito, E, Chandramouli, S. 登録日 2017-05-02 公開日 2017-07-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.99 Å) 主引用文献 Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2, 2017
8W9J	Crystal structure of human CLEC12A ectodomain complexed with 50C1 Fab 分子名称: Anti-human CLEC12A antibody 50C1 heavy chain, Anti-human CLEC12A antibody 50C1 light chain, C-type lectin domain family 12 member A 著者 Mori, S, Nagae, M, Yamasaki, S. 登録日 2023-09-05 公開日 2024-03-06 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 36, 2024

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