5VOC
Crystal structure of HCMV Pentamer in complex with neutralizing antibody 8I21 - Low resolution dataset for initial phasing by SAD
Summary for 5VOC
Entry DOI | 10.2210/pdb5voc/pdb |
Related | 5VOB 5VOD |
Descriptor | Envelope glycoprotein H, Envelope glycoprotein L, Envelope glycoprotein UL128, ... (9 entities in total) |
Functional Keywords | hcmv, neutralizing epitope, immunogen, viral entry, pentamer, vaccine, immune system, viral protein-immune system complex, viral protein/immune system |
Biological source | Human cytomegalovirus (HHV-5) More |
Cellular location | Virion membrane ; Single-pass type I membrane protein : Q6SW67 Virion membrane ; Peripheral membrane protein ; Extracellular side : Q68674 Virion : F5HET4 |
Total number of polymer chains | 7 |
Total formula weight | 234995.93 |
Authors | Malito, E.,Chandramouli, S. (deposition date: 2017-05-02, release date: 2017-07-05, Last modification date: 2020-07-29) |
Primary citation | Chandramouli, S.,Malito, E.,Nguyen, T.,Luisi, K.,Donnarumma, D.,Xing, Y.,Norais, N.,Yu, D.,Carfi, A. Structural basis for potent antibody-mediated neutralization of human cytomegalovirus. Sci Immunol, 2:-, 2017 Cited by PubMed: 28783665DOI: 10.1126/sciimmunol.aan1457 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.99 Å) |
Structure validation
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