5IBR
 
 | | Caspase 3 V266K | | 分子名称: | ACE-ASP-GLU-VAL-ASK, Caspase-3 | | 著者 | Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. | | 登録日 | 2016-02-22 | | 公開日 | 2016-10-26 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6XY3
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6MC9
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6TV7
 | | Crystal structure of rsGCaMP in the OFF state (illuminated) | | 分子名称: | CALCIUM ION, SODIUM ION, rsGCaMP | | 著者 | Janowski, R, Fuenzalida-Werner, J.P, Mishra, K, Stiel, A.C, Niessing, D. | | 登録日 | 2020-01-09 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Genetically encoded photo-switchable molecular sensors for optoacoustic and super-resolution imaging.
Nat.Biotechnol., 2021
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6XXX
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5IFP
 | | STRUCTURE OF BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | | 登録日 | 2016-02-26 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages.
FEBS J., 284, 2017
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6ZM9
 | | PHAGE SAM LYASE IN COMPLEX WITH S-METHYL-5'-THIOADENOSINE | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, Chains: A, PHOSPHATE ION, ... | | 著者 | Guo, X, Kanchugal P, S, Selmer, M. | | 登録日 | 2020-07-02 | | 公開日 | 2021-02-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.
Elife, 10, 2021
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6ZMG
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1IC4
 | | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX | | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | | 登録日 | 2001-03-30 | | 公開日 | 2001-07-18 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex.
J.Biol.Chem., 276, 2001
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1I1C
 | | NON-FCRN BINDING FC FRAGMENT OF RAT IGG2A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IG GAMMA-2A CHAIN C REGION | | 著者 | Martin, W.L, West Jr, A.P, Gan, L, Bjorkman, P.J. | | 登録日 | 2001-01-31 | | 公開日 | 2001-02-14 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.
Mol.Cell, 7, 2001
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6X93
 | | Interleukin-10 signaling complex with IL-10RA and IL-10RB | | 分子名称: | Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta | | 著者 | Saxton, R.A, Tsutsumi, N, Gati, C, Garcia, K.C. | | 登録日 | 2020-06-02 | | 公開日 | 2021-03-17 | | 最終更新日 | 2021-03-31 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.
Science, 371, 2021
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6ZNB
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6ZUJ
 | | Human serine racemase holoenzyme from 20% DMSO soak (XChem crystallographic fragment screen). | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DIMETHYL SULFOXIDE, ... | | 著者 | Koulouris, C.R, Bax, B.D, Roe, S.M, Atack, J.R. | | 登録日 | 2020-07-23 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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1I1A
 | | CRYSTAL STRUCTURE OF THE NEONATAL FC RECEPTOR COMPLEXED WITH A HETERODIMERIC FC | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Martin, W.L, West Jr, A.P, Gan, L, Bjorkman, P.J. | | 登録日 | 2001-01-31 | | 公開日 | 2001-02-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.
Mol.Cell, 7, 2001
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6ZSP
 | | Human serine racemase bound to ATP and malonate. | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... | | 著者 | Koulouris, C.R, Bax, B.D, Roe, S.M, Atack, J.R. | | 登録日 | 2020-07-16 | | 公開日 | 2021-03-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase.
Commun Biol, 5, 2022
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1I55
 | | CYTOCHROME C (TUNA) WITH 2ZN:1FE MIXED-METAL PORPHYRINS | | 分子名称: | CYTOCHROME C, HEME C, PROTOPORPHYRIN IX CONTAINING ZN | | 著者 | Crane, B.R, Tezcan, F.A, Winkler, J.R, Gray, H.B. | | 登録日 | 2001-02-24 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Electron tunneling in protein crystals.
Proc.Natl.Acad.Sci.USA, 98, 2001
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4XH5
 | | Crystal structure of Salmonella typhimurium propionate kinase A88G mutant, in complex with AMPPNP and propionate | | 分子名称: | GLYCEROL, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROPANOIC ACID, ... | | 著者 | Murthy, A.M, Mathivanan, S, Chittori, S, Savithri, H.S, Murthy, M.R.N. | | 登録日 | 2015-01-04 | | 公開日 | 2015-09-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structures of substrate- and nucleotide-bound propionate kinase from Salmonella typhimurium: substrate specificity and phosphate-transfer mechanism
Acta Crystallogr.,Sect.D, 71, 2015
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2JYO
 | | NMR Solution structure of Human MIP-3alpha/CCL20 | | 分子名称: | C-C motif chemokine 20 (Small-inducible cytokine A20) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Liver and activation-regulated chemokine) (CC chemokine LARC) (Beta chemokine exodus-1) | | 著者 | Chan, D.I, Hunter, H.N, Tack, B.F, Vogel, H.J. | | 登録日 | 2007-12-14 | | 公開日 | 2008-01-01 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Human macrophage inflammatory protein 3alpha: protein and peptide nuclear magnetic resonance solution structures, dimerization, dynamics, and anti-infective properties.
Antimicrob.Agents Chemother., 52, 2008
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6ZLV
 | | MreC | | 分子名称: | Rod shape-determining protein MreC | | 著者 | Estrozi, L.F, Contreras-Martel, C. | | 登録日 | 2020-07-01 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Self-association of MreC as a regulatory signal in bacterial cell wall elongation.
Nat Commun, 12, 2021
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6ZM0
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6VAB
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8FVI
 | | Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5 | | 分子名称: | Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ... | | 著者 | Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S. | | 登録日 | 2023-01-19 | | 公開日 | 2023-09-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
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5IFT
 | | STRUCTURE OF E298Q-BETA-GALACTOSIDASE FROM ASPERGILLUS NIGER IN COMPLEX WITH 3-b-Galactopyranosyl glucose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Rico-Diaz, A, Ramirez-Escudero, M, Vizoso Vazquez, A, Cerdan, M.E, Becerra, M, Sanz-Aparicio, J. | | 登録日 | 2016-02-26 | | 公開日 | 2017-04-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural features of Aspergillus niger beta-galactosidase define its activity against glycoside linkages.
FEBS J., 284, 2017
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6ALE
 | | A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model | | 分子名称: | (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-2, ... | | 著者 | Nam, Y.W, Zhang, M. | | 登録日 | 2017-08-07 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model.
Sci Rep, 8, 2018
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1IG3
 | | Mouse Thiamin Pyrophosphokinase Complexed with Thiamin | | 分子名称: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, SULFATE ION, thiamin pyrophosphokinase | | 著者 | Timm, D.E, Liu, J, Baker, L.-J, Harris, R.A. | | 登録日 | 2001-04-16 | | 公開日 | 2001-04-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of thiamin pyrophosphokinase.
J.Mol.Biol., 310, 2001
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