6XXX

1.25 Angstrom crystal structure of Ca/CaM A102V:RyR2 peptide complex

This is a non-PDB format compatible entry.

Summary for 6XXX

• Entry DOI: 10.2210/pdb6xxx/pdb
• Related: 6XXF
• Descriptor: Calmodulin-1, LYS-LYS-ALA-VAL-TRP-HIS-LYS-LEU-LEU-SER-LYS-GLN-ARG-LYS-ARG-ALA-VAL-VAL-ALA-CYS-PHE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: calcium-binding protein, cardiac muscle contraction, ryr2, metal binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 19546.03

Authors

Antonyuk, S.,Helassa, N. (deposition date: 2020-01-28, release date: 2021-02-10, Last modification date: 2024-01-24)

• Primary citation: Prakash, O.,Held, M.,McCormick, L.F.,Gupta, N.,Lian, L.Y.,Antonyuk, S.,Haynes, L.P.,Thomas, N.L.,Helassa, N.; CPVT-associated calmodulin variants N53I and A102V dysregulate Ca2+ signalling via different mechanisms.; J.Cell.Sci., 135:-, 2022; PubMed: 34888671; DOI: 10.1242/jcs.258796

Experimental method

X-RAY DIFFRACTION (1.25 Å)