6X93

Interleukin-10 signaling complex with IL-10RA and IL-10RB

Summary for 6X93

• Entry DOI: 10.2210/pdb6x93/pdb
• EMDB information: 22098
• Descriptor: Interleukin-10, Interleukin-10 receptor subunit alpha, Interleukin-10 receptor subunit beta (3 entities in total)
• Functional Keywords: il-10, cytokine, receptor, il-10ra, il-10rb, signaling
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 133540.54

Authors

Saxton, R.A.,Tsutsumi, N.,Gati, C.,Garcia, K.C. (deposition date: 2020-06-02, release date: 2021-03-17, Last modification date: 2021-03-31)

• Primary citation: Saxton, R.A.,Tsutsumi, N.,Su, L.L.,Abhiraman, G.C.,Mohan, K.,Henneberg, L.T.,Aduri, N.G.,Gati, C.,Garcia, K.C.; Structure-based decoupling of the pro- and anti-inflammatory functions of interleukin-10.; Science, 371:-, 2021; PubMed: 33737461; DOI: 10.1126/science.abc8433

Experimental method

ELECTRON MICROSCOPY (3.5 Å)