6X93
Interleukin-10 signaling complex with IL-10RA and IL-10RB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Interleukin-10 | polymer | 160 | 18778.5 | 2 | UniProt (P22301) Pfam (PF00726) | Homo sapiens (Human) | IL-10,Cytokine synthesis inhibitory factor,CSIF |
| 2 | B, E (B, E) | Interleukin-10 receptor subunit alpha | polymer | 214 | 24422.4 | 2 | UniProt (Q13651) Pfam (PF01108) | Homo sapiens (Human) | IL-10RA,CDw210a,Interleukin-10 receptor subunit 1,IL-10R1 |
| 3 | C, F (C, F) | Interleukin-10 receptor subunit beta | polymer | 201 | 23569.3 | 2 | UniProt (Q08334) Pfam (PF01108) Pfam (PF09294) | Homo sapiens (Human) | IL-10RB,Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,CRF2-4,Interleukin-10 receptor subunit 2,IL-10R2 |
Sequence modifications
A, D: 1 - 160 (UniProt: P22301)
C, F: 20 - 220 (UniProt: Q08334)
| PDB | External Database | Details |
|---|---|---|
| Tyr 18 | Asn 36 | conflict |
| Gln 92 | Asn 110 | conflict |
| Asp 100 | Thr 118 | conflict |
| Trp 104 | Arg 122 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 49 | Asn 49 | conflict |
| Gln 68 | Asn 68 | conflict |
| Gln 102 | Asn 102 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 133540.5 | |
| All* | Total formula weight | 133540.5 |
