6ZUJ
Human serine racemase holoenzyme from 20% DMSO soak (XChem crystallographic fragment screen).
This is a non-PDB format compatible entry.
Summary for 6ZUJ
Entry DOI | 10.2210/pdb6zuj/pdb |
Related | 6ZSP |
Descriptor | Serine racemase, TRIETHYLENE GLYCOL, DIMETHYL SULFOXIDE, ... (9 entities in total) |
Functional Keywords | plp-dependent, d-serine, isomerase, forebrain |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 153202.92 |
Authors | Koulouris, C.R.,Bax, B.D.,Roe, S.M.,Atack, J.R. (deposition date: 2020-07-23, release date: 2021-03-03, Last modification date: 2024-01-31) |
Primary citation | Koulouris, C.R.,Gardiner, S.E.,Harris, T.K.,Elvers, K.T.,Mark Roe, S.,Gillespie, J.A.,Ward, S.E.,Grubisha, O.,Nicholls, R.A.,Atack, J.R.,Bax, B.D. Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase. Commun Biol, 5:346-346, 2022 Cited by PubMed: 35410329DOI: 10.1038/s42003-022-03264-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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