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6ZUJ

Human serine racemase holoenzyme from 20% DMSO soak (XChem crystallographic fragment screen).

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(AAA, BBB, CCC, DDD)
Serine racemasepolymer34637684.04UniProt (Q9GZT4)
Pfam (PF00291)
Homo sapiens (Human)D-serine ammonia-lyase,D-serine dehydratase,L-serine ammonia-lyase,L-serine dehydratase
2DA, E, GA, NA, V
(CCC, AAA, DDD)
TRIETHYLENE GLYCOLnon-polymer150.25Chemie (PGE)
3F, HA
(AAA, DDD)
DIMETHYL SULFOXIDEnon-polymer78.12Chemie (DMS)
4G
(AAA)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5FA, H, R, W
(DDD, AAA, BBB, CCC)
CALCIUM IONnon-polymer40.14Chemie (CA)
6EA, I, O, P, S...
(DDD, AAA, BBB)
SODIUM IONnon-polymer23.06Chemie (NA)
7BA, IA, J, JA, K...
(CCC, DDD, AAA, BBB)
1,2-ETHANEDIOLnon-polymer62.114Chemie (EDO)
8AA, CA, N, U
(CCC, AAA)
GLYCEROLnon-polymer92.14Chemie (GOL)
9OA, PA, QA, RA
(AAA, BBB, CCC, DDD)
waterwater18.0792Chemie (HOH)
Sequence modifications
AAA, BBB, CCC, DDD: 1 - 340 (UniProt: Q9GZT4)
PDBExternal DatabaseDetails
Asp 2Cys 2engineered mutation
Asp 6Cys 6engineered mutation
His 341-expression tag
His 342-expression tag
His 343-expression tag
His 344-expression tag
His 345-expression tag
His 346-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight150735.9
Non-Polymers*Number of molecules36
Total formula weight2467.0
All*Total formula weight153202.9
*Water molecules are not included.

238582

PDB entries from 2025-07-09

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