PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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5CLV	Crystal Structure of KorA-operator DNA complex (KorA-OA) 分子名称: 5'-D(CP*CP*AP*AP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*TP*TP*GP*GP*)-3', TrfB transcriptional repressor protein 著者 White, S.A, Hyde, E.I, Rajasekar, K.V. 登録日 2015-07-16 公開日 2016-04-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Flexibility of KorA, a plasmid-encoded, global transcription regulator, in the presence and the absence of its operator. Nucleic Acids Res., 44, 2016
4YGI	Crystal Structure of SUVH5 SRA bound to fully hydroxymethylated CG DNA 分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH5, MAGNESIUM ION, ... 著者 Rajakumara, E. 登録日 2015-02-26 公開日 2016-02-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mechanistic insights into the recognition of 5-methylcytosine oxidation derivatives by the SUVH5 SRA domain Sci Rep, 6, 2016
2BJ1	NIKR IN OPEN CONFORMATION AND NICKEL BOUND TO HIGH-AFFINITY SITES 分子名称: CHLORIDE ION, NICKEL (II) ION, NICKEL RESPONSIVE REGULATOR 著者 Tahirov, T.H. 登録日 2005-01-27 公開日 2005-04-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005
2BJ9	NIKR with bound NICKEL and phosphate 分子名称: NICKEL (II) ION, NICKEL RESPONSIVE REGULATOR, PHOSPHATE ION, ... 著者 Tahirov, T.H, Chivers, P.T. 登録日 2005-01-31 公開日 2005-04-08 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of Pyrococcus Horikoshii Nikr: Nickel Sensing and Implications for the Regulation of DNA Recognition J.Mol.Biol., 348, 2005
7JO9	1:1 cGAS-nucleosome complex 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. 登録日 2020-08-06 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
4TU9	STRUCTURE OF U2AF65 VARIANT WITH BRU5G6 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DG*U)-3'), GLYCEROL, ... 著者 Jenkins, J.L, McLaughlin, K.J, Agrawal, A.A, Kielkopf, C.L. 登録日 2014-06-24 公開日 2014-11-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111, 2014
3ULQ	Crystal Structure of the Anti-Activator RapF Complexed with the Response Regulator ComA DNA Binding Domain 分子名称: MANGANESE (II) ION, Response regulator aspartate phosphatase F, Transcriptional regulatory protein ComA 著者 Baker, M.D, Neiditch, M.B. 登録日 2011-11-11 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of response regulator inhibition by a bacterial anti-activator protein. Plos Biol., 9, 2011
4TU8	STRUCTURE OF U2AF65 VARIANT WITH BRU5A6 DNA 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DA*U)-3'), ... 著者 MCLAUGHLIN, K.J, JENKINS, J.L, Agrawal, A.A, KIELKOPF, C.L. 登録日 2014-06-24 公開日 2014-11-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.918 Å) 主引用文献 Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111, 2014
8SOJ	Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA 分子名称: CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... 著者 Cai, S.W. 登録日 2023-04-28 公開日 2023-06-07 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 POT1 recruits and regulates CST-Pol alpha /Primase at human telomeres. Biorxiv, 2023
4TU7	Structure of U2AF65 D231V variant with BrU5 DNA 分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ... 著者 Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. 登録日 2014-06-24 公開日 2014-11-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.087 Å) 主引用文献 Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc.Natl.Acad.Sci.USA, 111, 2014
8XP8	Crystal structure of d(ACGmCCGT/ACGGCGT) in complex with Echinomycin 分子名称: 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*(5CM)P*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*GP*CP*GP*T)-3'), ... 著者 Hou, M.H, Lin, S.M, Neidle, H. 登録日 2024-01-03 公開日 2024-05-29 最終更新日 2024-08-28 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation. Nucleic Acids Res., 52, 2024
7JOA	2:1 cGAS-nucleosome complex 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. 登録日 2020-08-06 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
5D1J	CRYSTAL STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2-WT) COMPLEX WITH N-[5-[[[5-(1,1-DIMETHYLETHYL)-2-OXAZOLYL] METHYL]THIO]-2-THIAZOLYL]-4-PIPERIDINECARBOXAMIDE (BMS-387032) 分子名称: Cyclin-dependent kinase 2, N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide 著者 Sack, J.S. 登録日 2015-08-04 公開日 2015-08-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 N-(Cycloalkylamino)Acyl-2-Aminothiazole Inhibitors Of Cyclin-Dependent Kinase 2. N-[5-[[[5-(1,1-Dimethylethyl) -2-Oxazolyl]Methyl]Thio]-2-Thiazolyl]-4-Piperidinecarboxamide (Bms-387032), A Highly Efficacious And Selective Antitumor Agent J.Med.Chem., 47, 2004
1D58	THE MOLECULAR STRUCTURE OF A 4'-EPIADRIAMYCIN COMPLEX WITH D(TGATCA) AT 1.7 ANGSTROM RESOLUTION-COMPARISON WITH THE STRUCTURE OF 4'-EPIADRIAMYCIN D(TGTACA) AND D(CGATCG) COMPLEXES 分子名称: 4'-EPIDOXORUBICIN, DNA (5'-D(*TP*GP*AP*TP*CP*A)-3') 著者 Langlois D'Estaintot, B, Gallois, B, Brown, T, Hunter, W.N. 登録日 1992-02-20 公開日 1992-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The molecular structure of a 4'-epiadriamycin complex with d(TGATCA) at 1.7A resolution: comparison with the structure of 4'-epiadriamycin d(TGTACA) and d(CGATCG) complexes. Nucleic Acids Res., 20, 1992
3TQY	Structure of a single-stranded DNA-binding protein (ssb), from Coxiella burnetii 分子名称: Single-stranded DNA-binding protein 著者 Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.6001 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
8GLX	CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ... 著者 Shen, Y, Guarne, A. 登録日 2023-03-23 公開日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Assembly of the Tn7 targeting complex by a regulated stepwise process. Mol.Cell, 84, 2024
7Z7E	Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4 分子名称: DARPIN, Isoform 4 of Tumor protein 63, ZINC ION 著者 Strubel, A, Gebel, J, Chaikuad, A, Muenick, P, Doetsch, V. 登録日 2022-03-15 公開日 2022-06-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
6PUW	Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and Bictegravir (BIC) 分子名称: Bictegravir, Chimeric Sso7d and HIV-1 integrase, MAGNESIUM ION, ... 著者 Lyumkis, D, Jozwik, I.K, Passos, D. 登録日 2019-07-18 公開日 2020-02-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science, 367, 2020
6PUZ	Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f) 分子名称: 4-azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-[2-(phenylsulfonyl)ethyl]-1,8-naphthyridine-3-carboxamide, Chimeric Sso7d and HIV-1 integrase, MAGNESIUM ION, ... 著者 Lyumkis, D, Jozwik, I.K, Passos, D. 登録日 2019-07-18 公開日 2020-02-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science, 367, 2020
6PUY	Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ426 (compound 4d) 分子名称: 4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide, Chimeric Sso7d and HIV-1 integrase, MAGNESIUM ION, ... 著者 Lyumkis, D, Jozwik, I.K, Passos, D. 登録日 2019-07-18 公開日 2020-02-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science, 367, 2020
6PUT	Structure of HIV cleaved synaptic complex (CSC) intasome bound with calcium 分子名称: CALCIUM ION, Chimeric Sso7d and HIV-1 integrase, ZINC ION, ... 著者 Lyumkis, D, Jozwik, I.K, Passos, D. 登録日 2019-07-18 公開日 2020-02-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science, 367, 2020
7K9Y	GsI-IIC RT Template-Switching Complex (twinned) 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*CP*CP*AP*GP*GP*CP*AP*AP*C)-3'), MAGNESIUM ION, ... 著者 Stamos, J.L, Lentzsch, A.M. 登録日 2020-09-29 公開日 2021-08-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase. J.Biol.Chem., 297, 2021
6G0L	Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... 著者 Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. 登録日 2018-03-19 公開日 2018-08-22 最終更新日 2018-11-21 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
7BME	Crystal structure of a R18W mutant of the DNA-binding protein RemA from Geobacillus thermodenitrificans 分子名称: Putative regulatory protein GTNG_1019 著者 Altegoer, F, Mrusek, D, Bange, G. 登録日 2021-01-20 公開日 2021-08-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional characterization of the bacterial biofilm activator RemA. Nat Commun, 12, 2021
7ET6	Crystal structure of Arabidopsis TEM1 B3-DNA complex 分子名称: AP2/ERF and B3 domain-containing transcription repressor TEM1, FT-RY14-F, FT-RY14-R 著者 Hu, H, Du, J. 登録日 2021-05-12 公開日 2021-09-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis. Proc.Natl.Acad.Sci.USA, 118, 2021

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