PDB: 41646 件ウェブページステータス検索Chemie searchBIRD

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6Q2P	Crystal structure of mouse viperin bound to cytidine triphosphate and S-adenosylhomocysteine 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E. 登録日 2019-08-08 公開日 2020-01-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.452 Å) 主引用文献 Structural Basis of the Substrate Selectivity of Viperin. Biochemistry, 59, 2020
8G0K	Bacteroides multispecies type VI secretion system Ntox15 domain effector and immunity Tde1/Tdi1 分子名称: DUF1851 domain-containing protein, Ntox15 domain-containing protein 著者 Bosch, D.E, Mougous, J.D. 登録日 2023-01-31 公開日 2023-07-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales. Mbio, 14, 2023
8FC8	Cryo-EM structure of the human TRPV4 in complex with GSK1016790A 分子名称: CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4 著者 Kwon, D.H, Lee, S.-Y, Zhang, F. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nat Commun, 14, 2023
8FCA	Cryo-EM structure of the human TRPV4 - RhoA in complex with 4alpha-Phorbol 12,13-didecanoate 分子名称: (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(decanoyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily V member 4 著者 Kwon, D.H, Lee, S.-Y, Zhang, F. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nat Commun, 14, 2023
6OEV	Structure of human Patched1 in complex with native Sonic Hedgehog 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Protein patched homolog 1, ... 著者 Qi, X, Li, X. 登録日 2019-03-27 公開日 2019-04-17 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of human Patched and its complex with native palmitoylated sonic hedgehog. Nature, 560, 2018
1JHD	Crystal Structure of Bacterial ATP Sulfurylase from the Riftia pachyptila Symbiont 分子名称: BROMIDE ION, SULFATE ADENYLYLTRANSFERASE, SULFATE ION 著者 Beynon, J.D, MacRae, I.J, Huston, S.L, Nelson, D.C, Segel, I.H, Fisher, A.J. 登録日 2001-06-27 公開日 2001-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of ATP sulfurylase from the bacterial symbiont of the hydrothermal vent tubeworm Riftia pachyptila. Biochemistry, 40, 2001
1ME9	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with IMP bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, POTASSIUM ION 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
1MEW	Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with XMP and NAD bound 分子名称: INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ... 著者 Prosise, G.L, Luecke, H. 登録日 2002-08-08 公開日 2003-08-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism J.Mol.Biol., 326, 2003
5O90	Crystal structure of a P38alpha T185G mutant in complex with TAB1 peptide. 分子名称: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, Mitogen-activated protein kinase 14, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 著者 Nichols, C.E, De Nicola, G.F, Thapa, D. 登録日 2017-06-15 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 TAB1-Induced Autoactivation of p38 alpha Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185. Mol. Cell. Biol., 38, 2018
4WP8	Crystal structure of Adenylyl cyclase Ma1120 from Mycobacterium Avium in complex with 2'5'-DD-3'-ATP and Manganese ion 分子名称: 2',5'-dideoxyadenosine 3'-(tetrahydrogen triphosphate), CHLORIDE ION, MANGANESE (II) ION, ... 著者 Barathy, D.V, Bharambe, N.G, Suguna, K. 登録日 2014-10-17 公開日 2015-09-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase J.Struct.Biol., 190, 2015
1JQL	Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of beta-delta (1-140) 分子名称: DNA Polymerase III, BETA CHAIN, DELTA SUBUNIT 著者 Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J. 登録日 2001-08-07 公開日 2001-09-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
8UFP	Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride 分子名称: (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, GLYCEROL, Nitric oxide synthase, ... 著者 Li, H, Poulos, T.L. 登録日 2023-10-04 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
8UFR	Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride 分子名称: (7M)-4-methyl-7-(4-methyl-2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)quinolin-2-amine, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2023-10-04 公開日 2024-03-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.871 Å) 主引用文献 Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase. Biochemistry, 63, 2024
5O5P	Poliovirus type 3 (strain Saukett) stabilized virus-like particle in complex with the pocket factor compound GPP3 分子名称: 1-[5-[4-(ethoxyiminomethyl)phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazol-2-one, Capsid proteins, VP4, ... 著者 Bahar, M.W, Kotecha, A, Fry, E.E, Stuart, D.I. 登録日 2017-06-02 公開日 2017-07-12 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine. Nat Commun, 8, 2017
1KQD	Structure of Nitroreductase from E. cloacae Bound with 2e-Reduced Flavin Mononucleotide (FMN) 分子名称: FLAVIN MONONUCLEOTIDE, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE 著者 Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. 登録日 2002-01-04 公開日 2002-02-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of nitroreductase in three states: effects of inhibitor binding and reduction. J.Biol.Chem., 277, 2002
8DP5	Structure of the PEAK3/14-3-3 complex 分子名称: 14-3-3 protein beta/alpha, 14-3-3 protein epsilon, Protein PEAK3, ... 著者 Torosyan, H, Paul, M, Jura, N, Verba, K.A. 登録日 2022-07-14 公開日 2023-06-28 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3. Nat Commun, 14, 2023
8V7W	Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain C145A precursor, residues nsp4(-6)-1-199-6H 分子名称: Replicase polyprotein 1ab 著者 Kovalevsky, A, Coates, L. 登録日 2023-12-04 公開日 2024-05-29 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease. J.Mol.Biol., 436, 2024
2VGY	Crystal structure of the Yersinia enterocolitica Type III Secretion Translocator Chaperone SycD (alternative dimer) 分子名称: CHAPERONE SYCD 著者 Buttner, C.R, Sorg, I, Cornelis, G.R, Heinz, D.W, Niemann, H.H. 登録日 2007-11-16 公開日 2007-12-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Yersinia Enterocolitica Type III Secretion Chaperone Sycd J.Mol.Biol., 375, 2008
1KFB	CRYSTAL STRUCTURE OF ALPHAT183V MUTANT OF TRYPTOPHAN SYNTHASE FROM SALMONELLA TYPHIMURIUM WITH Indole Glycerol Phosphate 分子名称: INDOLE-3-GLYCEROL PHOSPHATE, PYRIDOXAL-5'-PHOSPHATE, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ... 著者 Kulik, V, Weyand, M, Siedel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. 登録日 2001-11-20 公開日 2003-01-07 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 On the Role of alphaTHR183 in the Allosteric Regulation and Catalytic Mechanism of Tryptophan Synthase J.Mol.Biol., 324, 2002
8V7T	Room-temperature X-ray structure of SARS-CoV-2 main protease catalytic domain (residues 1-199) 分子名称: Non-structural protein 7 著者 Kovalevsky, A, Coates, L. 登録日 2023-12-04 公開日 2024-05-29 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Visualizing the Active Site Oxyanion Loop Transition Upon Ensitrelvir Binding and Transient Dimerization of SARS-CoV-2 Main Protease. J.Mol.Biol., 436, 2024
1XKP	Crystal structure of the virulence factor YopN in complex with its heterodimeric chaperone SycN-YscB 分子名称: Chaperone protein sycN, Chaperone protein yscB, putative membrane-bound Yop targeting protein YopN 著者 Schubot, F.D, Jackson, M.W, Penrose, K.J, Cherry, S, Tropea, J.E, Plano, G.V, Waugh, D.S. 登録日 2004-09-29 公開日 2005-03-22 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis. J.Mol.Biol., 346, 2005
8DS6	Structure of the PEAK3 pseudokinase homodimer 分子名称: Protein PEAK3 著者 Torosyan, H, Paul, M, Jura, N, Verba, K.A. 登録日 2022-07-21 公開日 2023-06-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structural insights into regulation of the PEAK3 pseudokinase scaffold by 14-3-3. Nat Commun, 14, 2023
6B8N	Crystal Structure of the Ca2+/CaM:Kv7.4 (KCNQ4) AB Domain Complex, 10 uM CaCl2 soak 分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 4, ... 著者 Chang, A, Minor, D.L. 登録日 2017-10-09 公開日 2018-03-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 A Calmodulin C-Lobe Ca Neuron, 97, 2018
1PQ2	Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8 分子名称: Cytochrome P450 2C8, PALMITIC ACID, PHOSPHATE ION, ... 著者 Schoch, G.A, Yano, J.K, Wester, M.R, Griffin, K.J, Stout, C.D, Johnson, E.F. 登録日 2003-06-17 公開日 2004-01-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site J.Biol.Chem., 279, 2004
1KEY	Crystal Structure of Mouse Testis/Brain RNA-binding Protein (TB-RBP) 分子名称: translin 著者 Pascal, J.M, Hart, P.J, Hecht, N.B, Robertus, J.D. 登録日 2001-11-19 公開日 2002-07-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structure of TB-RBP, a Novel RNA-binding and Regulating Protein J.Mol.Biol., 319, 2002

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