1PQ2
Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Summary for 1PQ2
Entry DOI | 10.2210/pdb1pq2/pdb |
Related | 1DT6 1N6B |
Descriptor | Cytochrome P450 2C8, PHOSPHATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
Functional Keywords | cytochrome p450, cyp2c8, membrane protein, taxol 6-hydroxylase, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P10632 |
Total number of polymer chains | 2 |
Total formula weight | 109949.11 |
Authors | Schoch, G.A.,Yano, J.K.,Wester, M.R.,Griffin, K.J.,Stout, C.D.,Johnson, E.F. (deposition date: 2003-06-17, release date: 2004-01-13, Last modification date: 2023-08-16) |
Primary citation | Schoch, G.A.,Yano, J.K.,Wester, M.R.,Griffin, K.J.,Stout, C.D.,Johnson, E.F. Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site J.Biol.Chem., 279:9497-9503, 2004 Cited by PubMed: 14676196DOI: 10.1074/jbc.M312516200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report