1DT6

STRUCTURE OF MAMMALIAN CYTOCHROME P450 2C5

Summary for 1DT6

DescriptorCYTOCHROME P450 2C5, SAMARIUM (III) ION, SULFATE ION, ... (4 entities in total)
Functional Keywordsmembrane protein, progesterone 21-hydroxylase, benzo(a)pyrene hydroxylase, estradiol 2-hydroxylase, p450, cyp2c5, oxidoreductase
Biological sourceOryctolagus cuniculus (rabbit)
Total number of polymer chains1
Total molecular weight54939.29
Authors
Williams, P.A.,Cosme, J.,Sridhar, V.,Johnson, E.F.,McRee, D.E. (deposition date: 2000-01-11, release date: 2000-09-27, Last modification date: 2019-07-24)
Primary citation
Williams, P.A.,Cosme, J.,Sridhar, V.,Johnson, E.F.,McRee, D.E.
Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity.
Mol.Cell, 5:121-131, 2000
PubMed: 10678174 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(00)80408-6
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.30246 8.3% 15.8% 3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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