1DT6
STRUCTURE OF MAMMALIAN CYTOCHROME P450 2C5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CYTOCHROME P450 2C5 | polymer | 473 | 53884.3 | 1 | UniProt (P00179) Pfam (PF00067) In PDB | Oryctolagus cuniculus (rabbit) | PROGESTERONE 21-HYDROXYLASE, CYPIIC5 P450 1, P450IIC5 |
2 | A | SAMARIUM (III) ION | non-polymer | 150.4 | 1 | Chemie (SM) | |||
3 | A | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
4 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) |
Sequence modifications
A: 21 - 487 (UniProt: P00179)
PDB | External Database | Details |
---|---|---|
Met 19 | - | expression tag |
Ala 20 | - | expression tag |
Lys 22 | Gln 22 | engineered mutation |
Thr 23 | Asn 23 | engineered mutation |
Ser 25 | Gly 25 | engineered mutation |
Lys 26 | Arg 26 | engineered mutation |
Arg 97 | Thr 97 | engineered mutation |
His 202 | Asn 202 | engineered mutation |
Glu 206 | Arg 206 | engineered mutation |
Leu 207 | Ile 207 | engineered mutation |
Gly 209 | Ser 209 | engineered mutation |
Thr 210 | Ser 210 | engineered mutation |
Gln 252 | Glu 252 | engineered mutation |
His 488 | - | expression tag |
His 489 | - | expression tag |
His 490 | - | expression tag |
His 491 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 53884.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1055.0 | |
All* | Total formula weight | 54939.3 |