1DT6
STRUCTURE OF MAMMALIAN CYTOCHROME P450 2C5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYTOCHROME P450 2C5 | polymer | 473 | 53884.3 | 1 | UniProt (P00179) Pfam (PF00067) | Oryctolagus cuniculus (rabbit) | PROGESTERONE 21-HYDROXYLASE, CYPIIC5 P450 1, P450IIC5 |
| 2 | B (A) | SAMARIUM (III) ION | non-polymer | 150.4 | 1 | Chemie (SM) | |||
| 3 | C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) |
Sequence modifications
A: 21 - 487 (UniProt: P00179)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | expression tag |
| Ala 20 | - | expression tag |
| Lys 22 | Gln 22 | engineered mutation |
| Thr 23 | Asn 23 | engineered mutation |
| Ser 25 | Gly 25 | engineered mutation |
| Lys 26 | Arg 26 | engineered mutation |
| Arg 97 | Thr 97 | engineered mutation |
| His 202 | Asn 202 | engineered mutation |
| Glu 206 | Arg 206 | engineered mutation |
| Leu 207 | Ile 207 | engineered mutation |
| Gly 209 | Ser 209 | engineered mutation |
| Thr 210 | Ser 210 | engineered mutation |
| Gln 252 | Glu 252 | engineered mutation |
| His 488 | - | expression tag |
| His 489 | - | expression tag |
| His 490 | - | expression tag |
| His 491 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 53884.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1055.0 | |
| All* | Total formula weight | 54939.3 |
