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5EY1
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Crystal structure of CodY from Staphylococcus aureus with GTP and Ile
分子名称: GTP-sensing transcriptional pleiotropic repressor CodY, GUANOSINE-5'-TRIPHOSPHATE, ISOLEUCINE
著者Han, A, Hwang, K.Y.
登録日2015-11-24
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism
Nucleic Acids Res., 44, 2016
1HZW
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CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE
分子名称: PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Almog, R, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P.
登録日2001-01-26
公開日2001-05-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci., 10, 2001
1I00
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CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX
著者Almog, R.A, Waddling, C.A, Maley, F, Maley, G.F, Van Roey, P.
登録日2001-01-27
公開日2001-05-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP.
Protein Sci., 10, 2001
5EP2
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Quorum-Sensing Signal Integrator LuxO - Catalytic Domain in Complex with AzaU Inhibitor
分子名称: 2,2-dimethylpropyl 2-[[3,5-bis(oxidanylidene)-2~{H}-1,2,4-triazin-6-yl]sulfanyl]ethanoate, ACETATE ION, Putative repressor protein luxO
著者Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M.
登録日2015-11-11
公開日2016-04-20
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.421 Å)
主引用文献Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
8HXX
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Cryo-EM structure of the histone deacetylase complex Rpd3S
分子名称: Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
3BBX
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The Hsp15 protein fitted into the low resolution Cryo-EM map of the 50S.nc-tRNA.Hsp15 complex
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Jiang, L, Abrahams, J.P.
登録日2007-11-11
公開日2008-10-21
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Recycling of Aborted Ribosomal 50S Subunit-Nascent Chain-tRNA Complexes by the Heat Shock Protein Hsp15.
J.Mol.Biol., 386, 2009
3QPH
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BU of 3qph by Molmil
The three-dimensional structure of TrmB, a global transcriptional regulator of the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose
分子名称: ACETATE ION, GLYCEROL, TrmB, ...
著者Krug, M, Lee, S.-J, Boos, W, Welte, W, Diederichs, K.
登録日2011-02-13
公開日2012-05-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.992 Å)
主引用文献The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.
Protein Sci., 22, 2013
5TZD
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Structure of the WT S. venezulae BldD-(CTD-c-di-GMP)2 assembly intermediate
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
著者Schumacher, M.
登録日2016-11-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
3ITG
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Structure the proline utilization A proline dehydrogenase domain (PutA86-630) inactivated with N-propargylglycine
分子名称: Bifunctional protein putA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
著者Tanner, J.J.
登録日2009-08-28
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.
Biochemistry, 49, 2010
3GZ8
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Cocrystal structure of NUDIX domain of Shewanella oneidensis NrtR complexed with ADP ribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, MutT/nudix family protein
著者Huang, N, Zhang, H.
登録日2009-04-06
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structure and function of an ADP-ribose-dependent transcriptional regulator of NAD metabolism
Structure, 17, 2009
3HZI
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Structure of mdt protein
分子名称: 5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3', ADENOSINE-5'-TRIPHOSPHATE, HTH-type transcriptional regulator hipB, ...
著者Schumacher, M.A.
登録日2009-06-23
公開日2009-07-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB.
Science, 323, 2009
5TZF
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Structure of the BldD CTD(D116A)-(c-di-GMP)2 intermediate, form 1
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein
著者Schumacher, M.A.
登録日2016-11-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
2F3X
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Crystal structure of FapR (in complex with effector)- a global regulator of fatty acid biosynthesis in B. subtilis
分子名称: MALONYL-COENZYME A, Transcription factor fapR
著者Buschiazzo, A, Guerin, M.E, Alzari, P.M.
登録日2005-11-22
公開日2006-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of lipid biosynthesis regulation in Gram-positive bacteria.
Embo J., 25, 2006
5TZG
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Structure of the BldD CTD(D116A)-(c-di-GMP)2, form 2
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), DNA-binding protein, ZINC ION
著者Schumacher, M.A.
登録日2016-11-21
公開日2017-04-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
Nucleic Acids Res., 45, 2017
3GZ6
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BU of 3gz6 by Molmil
Crystal structure of Shewanella oneidensis NrtR complexed with a 27mer DNA
分子名称: DNA (27-MER), MutT/nudix family protein, SODIUM ION
著者Huang, N, Zhang, H.
登録日2009-04-06
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structure and function of an ADP-ribose-dependent transcriptional regulator of NAD metabolism
Structure, 17, 2009
2C2T
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Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-((7,8-dicarbaundecaboran-7-yl)methyl)-6-methylpyrimidine, a novel boron containing, nonclassical Antifolate
分子名称: (S)-2,4-DIAMINO-5-((7,8-DICARBAUNDECABORAN-7-YL)METHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ...
著者leung, A.K.W, reynolds, R.C, riordan, J.M, borhani, D.W.
登録日2005-09-30
公開日2007-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation.
J.Med.Chem., 50, 2007
6BW3
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Crystal structure of RBBP4 in complex with PRDM3 N-terminal peptide
分子名称: Histone-binding protein RBBP4, MDS1 and EVI1 complex locus protein MDS1, UNKNOWN ATOM OR ION
著者Ivanochko, D, Halabelian, L, Hutchinson, A, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2017-12-14
公開日2017-12-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.
Nucleic Acids Res., 47, 2019
2C2S
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Human Dihydrofolate Reductase Complexed With NADPH and 2,4-Diamino-5-(1-o-carboranylmethyl)-6-methylpyrimidine, A novel boron containing, nonclassical Antifolate
分子名称: 2,4-DIAMINO-5-(1-O-CARBORANYLMETHYL)-6-METHYLPYRIMIDINE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ...
著者Leung, A.K.W, Reynolds, R.C, Riordan, J.M, Borhani, D.W.
登録日2005-09-29
公開日2007-04-10
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation.
J.Med.Chem., 50, 2007
6EI0
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Cytosolic copper storage protein Csp from Streptomyces lividans: apo form
分子名称: Cytosolic copper storage protein (Ccsp), GLYCEROL, SULFATE ION, ...
著者Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R.
登録日2017-09-15
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans.
Metallomics, 10, 2018
6EK9
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Cytosolic copper storage protein Csp from Streptomyces lividans: Cu loaded form
分子名称: COPPER (I) ION, Cytosolic copper storage protein
著者Straw, M.L, Chaplin, A.K, Hough, M.A, Worrall, J.A.R.
登録日2017-09-25
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans.
Metallomics, 10, 2018
8DS8
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Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
分子名称: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
著者Song, J.K, Lu, J.W.
登録日2022-07-21
公開日2023-08-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
5VLY
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Asymmetric unit for the coat proteins of phage Qbeta
分子名称: Capsid protein
著者Cui, Z, Zhang, J.
登録日2017-04-26
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of Q beta virions, virus-like particles, and the Q beta-MurA complex reveal internal coat proteins and the mechanism of host lysis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VLZ
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Backbone model for phage Qbeta capsid
分子名称: Capsid protein, Maturation protein A2
著者Cui, Z, Zhang, J.
登録日2017-04-26
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structures of Q beta virions, virus-like particles, and the Q beta-MurA complex reveal internal coat proteins and the mechanism of host lysis.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2RBF
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Structure of the ribbon-helix-helix domain of Escherichia coli PutA (PutA52) complexed with operator DNA (O2)
分子名称: Bifunctional protein putA, DNA (5'-D(*DTP*DT*DTP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DCP*DAP*DAP*DA)-3'), DNA (5'-D(*DTP*DTP*DTP*DGP*DAP*DAP*DAP*DGP*DGP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DAP*DAP*DA)-3')
著者Tanner, J.J.
登録日2007-09-18
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of the transcriptional regulation of the proline utilization regulon by multifunctional PutA.
J.Mol.Biol., 381, 2008
2O99
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The crystal structure of E.coli IclR C-terminal fragment in complex with glyoxylate
分子名称: 1,2-ETHANEDIOL, Acetate operon repressor, GLYCOLIC ACID
著者Lunin, V.V, Ezersky, A, Evdokimova, E, Kudritska, M, Savchenko, A.
登録日2006-12-13
公開日2007-04-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Glyoxylate and Pyruvate Are Antagonistic Effectors of the Escherichia coli IclR Transcriptional Regulator.
J.Biol.Chem., 282, 2007

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