1HZW
CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE
Summary for 1HZW
| Entry DOI | 10.2210/pdb1hzw/pdb |
| Descriptor | THYMIDYLATE SYNTHASE, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | thymidylate synthase, human, uncomplexed, open conformation, delta(7-29) mutant, transferase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 66568.08 |
| Authors | Almog, R.,Waddling, C.A.,Maley, F.,Maley, G.F.,Van Roey, P. (deposition date: 2001-01-26, release date: 2001-05-09, Last modification date: 2024-04-03) |
| Primary citation | Almog, R.,Waddling, C.A.,Maley, F.,Maley, G.F.,Van Roey, P. Crystal structure of a deletion mutant of human thymidylate synthase Delta (7-29) and its ternary complex with Tomudex and dUMP. Protein Sci., 10:988-996, 2001 Cited by PubMed: 11316879DOI: 10.1110/ps.47601 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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