6BW3

Crystal structure of RBBP4 in complex with PRDM3 N-terminal peptide

Summary for 6BW3

Entry DOI	10.2210/pdb6bw3/pdb
Descriptor	Histone-binding protein RBBP4, MDS1 and EVI1 complex locus protein MDS1, UNKNOWN ATOM OR ION, ... (4 entities in total)
Functional Keywords	nurd, complex, epigenetics, structural genomics, structural genomics consortium, sgc, gene regulation, histone-binding protein, chromatin regulator, nucleus, repressor, wd repeat
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	98466.70
Authors	Ivanochko, D.,Halabelian, L.,Hutchinson, A.,Seitova, A.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Structural Genomics Consortium (SGC) (deposition date: 2017-12-14, release date: 2017-12-27, Last modification date: 2023-10-04)
Primary citation	Ivanochko, D.,Halabelian, L.,Henderson, E.,Savitsky, P.,Jain, H.,Marcon, E.,Duan, S.,Hutchinson, A.,Seitova, A.,Barsyte-Lovejoy, D.,Filippakopoulos, P.,Greenblatt, J.,Lima-Fernandes, E.,Arrowsmith, C.H. Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex. Nucleic Acids Res., 47:1225-1238, 2019 Cited by PubMed: 30462309 DOI: 10.1093/nar/gky1192 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation