PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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8HXY	Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome 分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
5U8S	Structure of eukaryotic CMG helicase at a replication fork 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (26-MER), ... 著者 Li, H, Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, O'Donnell, M.E. 登録日 2016-12-14 公開日 2017-01-25 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4LUZ	Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions 分子名称: 5-(4-{[4-(5-carboxyfuran-2-yl)benzyl]oxy}phenyl)-1-(3-methylphenyl)-1H-pyrazole-3-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit 著者 Feldkamp, M.D, Frank, A.O, Kennedy, J.P, Waterson, A.G, Olejnczak, E.O, Pelz, N.F, Patrone, J.D, Vangamudi, B, Camper, D.V, Rossanese, O.W, Fesik, S.W, Chazin, W.J. 登録日 2013-07-25 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J.Med.Chem., 56, 2013
4LW1	Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions 分子名称: 5-(3-chloro-4-fluorophenyl)furan-2-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit 著者 Feldkamp, M.D, Frank, A.O, Kennedy, J.P, Waterson, A.G, Olejnczak, E.O, Pelz, N.F, Patrone, J.D, Vangamudi, B, Camper, D.V, Rossanese, O.W, Fesik, S.W, Chazin, W.J. 登録日 2013-07-26 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.631 Å) 主引用文献 Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J.Med.Chem., 56, 2013
4LWC	Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein Interactions 分子名称: 5-[3-chloro-4-({4-[1-(3,4-dichlorophenyl)-1H-pyrazol-5-yl]benzyl}carbamothioyl)phenyl]furan-2-carboxylic acid, Replication protein A 70 kDa DNA-binding subunit 著者 Feldkamp, M.D, Frank, A.O, Kennedy, J.P, Waterson, A.G, Olejnczak, E.O, Pelz, N.F, Patrone, J.D, Vangamudi, B, Camper, D.V, Rossanese, O.W, Fesik, S.W, Chazin, W.J. 登録日 2013-07-26 公開日 2013-12-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach. J.Med.Chem., 56, 2013
8OW1	Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. 分子名称: C0N3, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ... 著者 Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D. 登録日 2023-04-26 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere. Sci Adv, 9, 2023
3NH2	Crystal structure of RNase T in complex with a stem DNA with a 3' overhang 分子名称: 5'-D(P*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T 著者 Hsiao, Y.-Y, Yuan, H.S. 登録日 2010-06-14 公開日 2011-02-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation Nat.Chem.Biol., 7, 2011
3NH0	Crystal structure of RNase T in complex with a non-preferred ssDNA (AAC) 分子名称: 5'-D(*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T 著者 Hsiao, Y.-Y, Yuan, H.S. 登録日 2010-06-14 公開日 2011-02-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation Nat.Chem.Biol., 7, 2011
5YUN	Crystal structure of SSB complexed with myc 分子名称: 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Single-stranded DNA-binding protein 著者 Huang, Y.H, Huang, C.Y. 登録日 2017-11-22 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Crystal structure of SSB complexed with inhibitor myricetin. Biochem. Biophys. Res. Commun., 504, 2018
3NGZ	Crystal structure of RNase T in complex with a non-preferred ssDNA (GC) with one Mg in the active site 分子名称: 5'-D(P*GP*C)-3', COBALT (II) ION, MAGNESIUM ION, ... 著者 Hsiao, Y.-Y, Yuan, H.S. 登録日 2010-06-14 公開日 2011-02-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation Nat.Chem.Biol., 7, 2011
3NH1	Crystal structure of RNase T in complex with a preferred ssDNA (TAGG) with two Mg in the active site 分子名称: 5'-D(*TP*TP*AP*TP*AP*GP*G)-3', MAGNESIUM ION, Ribonuclease T 著者 Hsiao, Y.-Y, Yuan, H.S. 登録日 2010-06-14 公開日 2011-02-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.107 Å) 主引用文献 Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation Nat.Chem.Biol., 7, 2011
2AS5	Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA. 分子名称: 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', 5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', Forkhead box protein P2, ... 著者 Wu, Y, Stroud, J.C, Borde, M, Bates, D.L, Guo, L, Han, A, Rao, A, Chen, L. 登録日 2005-08-22 公開日 2006-08-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT. Cell(Cambridge,Mass.), 126, 2006
4L9J	Crystal structure of S. aureus MepR in DNA-binding conformation 分子名称: MepR 著者 Birukou, I, Brennan, R.G. 登録日 2013-06-18 公開日 2013-09-11 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus. MBio, 4, 2013
5FUR	Structure of human TFIID-IIA bound to core promoter DNA 分子名称: SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ... 著者 Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E. 登録日 2016-01-29 公開日 2016-04-06 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (8.5 Å) 主引用文献 Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly. Nature, 531, 2016
6V92	RSC-NCP 分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC14, ... 著者 Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E. 登録日 2019-12-13 公開日 2020-01-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. Elife, 8, 2019
7PDS	The structure of PriRep1 with dsDNA 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Similar to D. nodosus vapE, ... 著者 Qiao, C.C, Mir Sanchis, I. 登録日 2021-08-06 公開日 2022-07-13 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Staphylococcal self-loading helicases couple the staircase mechanism with inter domain high flexibility. Nucleic Acids Res., 50, 2022
2HZD	NMR structure of the DNA-binding TEA domain and insights into TEF-1 function 分子名称: Transcriptional enhancer factor TEF-1 著者 Anbanandam, A, Veeraraghavan, S. 登録日 2006-08-08 公開日 2006-10-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
5U8T	Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications 分子名称: Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ... 著者 Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E. 登録日 2016-12-15 公開日 2017-02-08 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6BOV	Human APE1 substrate complex with an A/G mismatch adjacent the THF 分子名称: 21-mer DNA, DI(HYDROXYETHYL)ETHER, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.975 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6BOQ	Human APE1 substrate complex with an A/A mismatch adjacent the THF 分子名称: 1,2-ETHANEDIOL, 21-mer DNA, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6BOR	Human APE1 substrate complex with an G/G mismatch adjacent the THF 分子名称: 1,2-ETHANEDIOL, 21-mer DNA, CHLORIDE ION, ... 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6BOT	Human APE1 substrate complex with an C/C mismatch adjacent the THF 分子名称: 1,2-ETHANEDIOL, 21-mer DNA, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6BOW	Human APE1 substrate complex with an T/T mismatch adjacent the THF 分子名称: 21-mer DNA, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6BOS	Human APE1 substrate complex with an A/C mismatch adjacent the THF 分子名称: 21-mer DNA, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018
6BOU	Human APE1 substrate complex with an T/C mismatch adjacent the THF 分子名称: 21-mer DNA, DNA-(apurinic or apyrimidinic site) lyase 著者 Freudenthal, B.D, Whitaker, A.M, Fairlamb, M.S. 登録日 2017-11-20 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.538 Å) 主引用文献 Apurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches. Acta Crystallogr D Struct Biol, 74, 2018

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