5U8T

Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications

Summary for 5U8T

Entry DOI	10.2210/pdb5u8t/pdb
EMDB information	8519
Descriptor	DNA replication licensing factor MCM2, DNA replication complex GINS protein SLD5, Cell division control protein 45, ... (13 entities in total)
Functional Keywords	cmg helicase, replisome, origin initiation, dna polymerase, dna replication, replication
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	12
Total formula weight	791714.54
Authors	Li, B.,Georgescu, R.,Yuan, Z.,Santos, R.,Sun, J.,Zhang, D.,Yurieva, O.,Li, H.,O'Donnell, M.E. (deposition date: 2016-12-15, release date: 2017-02-08, Last modification date: 2019-12-18)
Primary citation	Georgescu, R.,Yuan, Z.,Bai, L.,de Luna Almeida Santos, R.,Sun, J.,Zhang, D.,Yurieva, O.,Li, H.,O'Donnell, M.E. Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proc. Natl. Acad. Sci. U.S.A., 114:E697-E706, 2017 Cited by PubMed: 28096349 DOI: 10.1073/pnas.1620500114 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.9 Å)

Structure validation