5NKW
 
 | | X-ray crystal structure of an AA9 LPMO | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity 9, CHLORIDE ION, ... | | 著者 | Tandrup, T, Frandsen, K.E.H, Poulsen, J.-C.N, Lo Leggio, L. | | 登録日 | 2017-04-03 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates.
Nat Commun, 8, 2017
|
|
5JE3
 | | Crystal structure of Burkholderia glumae ToxA Y7A mutant with bound S-adenosylhomocysteine (SAH) | | 分子名称: | Methyl transferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E. | | 登録日 | 2016-04-17 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.792 Å) | | 主引用文献 | Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry, 55, 2016
|
|
8UM3
 | | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z203039992 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 6-chlorotetrazolo[1,5-b]pyridazine, ... | | 著者 | Godoy, A.S, Noske, G.D, Fairhead, M, Lithgo, R.M, Koekemoer, L, Aschenbrenner, J.C, Balcomb, B.H, Marples, P.G, Ni, X, Tomlinson, C.W.E, Wild, C, Mesquita, N.C.M.R, Oliva, G, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2023-10-17 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.925 Å) | | 主引用文献 | PanDDA analysis -- Crystal Structure of Zika virus NS3 Helicase in complex with Z203039992
To Be Published
|
|
6H3Z
 | | Crystal structure of a C-terminal MIF4G domain in NOT1 | | 分子名称: | CCR4-not transcription complex subunit 1, SODIUM ION | | 著者 | Raisch, T, Sandmeir, F, Weichenrieder, O, Valkov, E, Izaurralde, E. | | 登録日 | 2018-07-19 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex.
J. Struct. Biol., 204, 2018
|
|
8DST
 | |
6MG8
 | | Structural basis for cholesterol transport-like activity of the Hedgehog receptor Patched | | 分子名称: | CHOLESTEROL, Protein patched homolog 1 | | 著者 | Zhang, Y, Bulkley, D, Xin, Y, Roberts, K.J, Asarnow, D.E, Sharma, A, Myers, B.R, Cho, W, Cheng, Y, Beachy, P.A. | | 登録日 | 2018-09-13 | | 公開日 | 2018-11-28 | | 最終更新日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched.
Cell, 175, 2018
|
|
7UPZ
 | | Structural basis for cell type specific DNA binding of C/EBPbeta: the case of cell cycle inhibitor p15INK4b promoter | | 分子名称: | CCAAT/enhancer-binding protein beta, DNA (5'-D(*AP*TP*TP*CP*TP*TP*AP*AP*GP*AP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*TP*CP*TP*TP*TP*CP*TP*TP*AP*AP*GP*AP*A)-3') | | 著者 | Lountos, G.T, Cherry, S, Tropea, J.E, Wlodawer, A, Miller, M. | | 登録日 | 2022-04-18 | | 公開日 | 2022-11-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.487 Å) | | 主引用文献 | Structural basis for cell type specific DNA binding of C/EBP beta : The case of cell cycle inhibitor p15INK4b promoter.
J.Struct.Biol., 214, 2022
|
|
5N02
 | | Crystal structure of the decarboxylase AibA/AibB C56S variant | | 分子名称: | ACETATE ION, Glutaconate CoA-transferase family, subunit A, ... | | 著者 | Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. | | 登録日 | 2017-02-02 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus.
Angew. Chem. Int. Ed. Engl., 56, 2017
|
|
6MA1
 | | Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) and inhibitor 4a | | 分子名称: | Host Cell Factor 1 peptide, N-[(2R)-2-{[(7-chloro-2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]amino}-2-(2-methoxyphenyl)acetyl]-N-[(thiophen-2-yl)methyl]glycine, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | | 著者 | Martin, S.E.S, Lazarus, M.B, Walker, S. | | 登録日 | 2018-08-25 | | 公開日 | 2018-10-17 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors.
J. Am. Chem. Soc., 140, 2018
|
|
6MED
 | | Crystal structure of broadly neutralizing antibody HEPC3 | | 分子名称: | SULFATE ION, antibody HEPC3 Heavy Chain, antibody HEPC3 Light Chain | | 著者 | Flyak, A.I, Bjorkman, P.J. | | 登録日 | 2018-09-06 | | 公開日 | 2018-11-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design.
Cell Host Microbe, 24, 2018
|
|
6QZL
 | | Structure of the H1 domain of human KCTD12 | | 分子名称: | BTB/POZ domain-containing protein KCTD12 | | 著者 | Pinkas, D.M, Bufton, J.C, Fox, A.E, Newman, J.A, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC) | | 登録日 | 2019-03-11 | | 公開日 | 2019-03-20 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structure of the H1 domain of human KCTD12
To be published
|
|
8EC3
 | |
6MFS
 | | Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2) | | 分子名称: | PHOSPHATE ION, Talin-1 fusion, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Izard, T, Chinthalapudi, K, Rangarajan, E.S. | | 登録日 | 2018-09-12 | | 公開日 | 2018-09-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6QVL
 | | Human SHMT2 in complex with pemetrexed | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Scaletti, E, Jemth, A.S, Helleday, T, Stenmark, P. | | 登録日 | 2019-03-03 | | 公開日 | 2019-09-04 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs.
Febs Lett., 593, 2019
|
|
6MFJ
 | |
5JIC
 | | Staphylococcus aureus Type II pantothenate kinase in complex with a pantothenate analog | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(5-methoxypentyl)-beta-alaninamide, ... | | 著者 | Hughes, S.J, Antoshchenko, T, Mottaghi, K, Barnard, L, Strauss, E, Park, H. | | 登録日 | 2016-04-22 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product.
Acs Infect Dis., 2, 2016
|
|
8E5G
 | | Cryo-EM of A. veneficus cytochrome filament | | 分子名称: | HEME C, c-type cytochrome | | 著者 | Wang, F, Baquero, D.P, Krupovic, M, Egelman, E.H. | | 登録日 | 2022-08-22 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Extracellular cytochrome nanowires appear to be ubiquitous in prokaryotes.
Cell, 186, 2023
|
|
6VC0
 | |
5JJ6
 | |
6MF8
 | | TCR alpha transmembrane domain | | 分子名称: | T-cell receptor alpha chain C region | | 著者 | Brazin, K.N, Reinherz, E.L. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity, 49, 2018
|
|
5JJF
 | | Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) - M state | | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | 登録日 | 2016-04-23 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
|
|
8B7V
 | | Automated simulation-based refinement of maltoporin into a cryo-EM density | | 分子名称: | Maltoporin | | 著者 | Yvonnesdotter, L, Rovsnik, U, Blau, C, Lycksell, M, Howard, R.J, Lindahl, E. | | 登録日 | 2022-10-03 | | 公開日 | 2023-06-21 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Automated simulation-based membrane protein refinement into cryo-EM data.
Biophys.J., 122, 2023
|
|
6LTQ
 | | Crystal structure of pyrrolidone carboxyl peptidase from thermophilic keratin degrading bacterium Fervidobacterium islandicum AW-1 (FiPcp) | | 分子名称: | GLYCEROL, PENTAETHYLENE GLYCOL, Pyroglutamyl-peptidase I | | 著者 | Dhanasingh, I, Jin, H.S, Lee, D.W, Lee, S.H. | | 登録日 | 2020-01-23 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of oxidized pyrrolidone carboxypeptidase from Fervidobacterium islandicum AW-1 reveals unique structural features for thermostability and keratinolysis.
Biochem.Biophys.Res.Commun., 540, 2021
|
|
5MX1
 | |
8DTA
 | |
