6MG8

Structural basis for cholesterol transport-like activity of the Hedgehog receptor Patched

Summary for 6MG8

Entry DOI	10.2210/pdb6mg8/pdb
EMDB information	9111
Descriptor	Protein patched homolog 1, CHOLESTEROL (2 entities in total)
Functional Keywords	receptor membrane protein, membrane protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	1
Total formula weight	146904.46
Authors	Zhang, Y.,Bulkley, D.,Xin, Y.,Roberts, K.J.,Asarnow, D.E.,Sharma, A.,Myers, B.R.,Cho, W.,Cheng, Y.,Beachy, P.A. (deposition date: 2018-09-13, release date: 2018-11-28, Last modification date: 2022-03-16)
Primary citation	Zhang, Y.,Bulkley, D.P.,Xin, Y.,Roberts, K.J.,Asarnow, D.E.,Sharma, A.,Myers, B.R.,Cho, W.,Cheng, Y.,Beachy, P.A. Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched. Cell, 175:1352-1364.e14, 2018 Cited by PubMed: 30415841 DOI: 10.1016/j.cell.2018.10.026 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation