PDB: 8880 件ウェブページステータス検索Chemie searchBIRD

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5T2C	CryoEM structure of the human ribosome at 3.6 Angstrom resolution 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Zhang, X, Lai, M, Zhou, Z.H. 登録日 2016-08-23 公開日 2017-01-25 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
8HK1	The cryo-EM structure of human pre-17S U2 snRNP 分子名称: ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... 著者 Zhang, X, Zhan, X, Shi, Y. 登録日 2022-11-24 公開日 2023-03-08 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly. Nat Commun, 14, 2023
7OMG	Crystal structure of KOD DNA Polymerase in a ternary complex with an Uracil containing template 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, ... 著者 Betz, K, Kropp, H.M, Diederichs, K, Marx, A. 登録日 2021-05-22 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
7OMB	Crystal structure of KOD DNA Polymerase in a ternary complex with a p/t duplex containing an extended 5' single stranded template overhang 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, ... 著者 Betz, K, Kropp, H.M, Diederichs, K, Marx, A. 登録日 2021-05-21 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural Basis for The Recognition of Deaminated Nucleobases by An Archaeal DNA Polymerase. Chembiochem, 22, 2021
6H4N	Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - 70S Hibernating E. coli Ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... 著者 Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, N.D. 登録日 2018-07-22 公開日 2018-09-05 最終更新日 2018-10-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1. Nat Microbiol, 3, 2018
7RDQ	Cryo-EM structure of Thermus thermophilus reiterative transcription complex with 11nt oligo-G RNA 分子名称: DNA (31-MER) nontemplate strand, DNA (31-MER) template strand, DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-07-10 公開日 2022-02-02 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
6DV9	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
8DY7	Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9	Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors 分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Campbell, E.A. 登録日 2022-08-03 公開日 2023-03-01 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB. Proc.Natl.Acad.Sci.USA, 120, 2023
6JBQ	CryoEM structure of Escherichia coli sigmaE transcription initiation complex containing 5nt of RNA 分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2019-01-26 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res., 47, 2019
6JCX	Mycobacterium tuberculosis transcription initiation complex with ECF sigma factor sigma H and 6nt RNA 分子名称: DNA (5'-D(*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2019-01-30 公開日 2019-05-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.903 Å) 主引用文献 Structures and mechanism of transcription initiation by bacterial ECF factors. Nucleic Acids Res., 47, 2019
5I2D	Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo 分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Feng, Y, Zhang, Y, Ebright, R.H. 登録日 2016-02-08 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.405 Å) 主引用文献 Structural basis of transcription activation. Science, 352, 2016
9F6E	Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation) 分子名称: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6D	Human DNA polymerase epsilon bound to DNA and PCNA (open conformation) 分子名称: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6F	Human DNA polymerase epsilon bound to DNA and PCNA (closed conformation) 分子名称: 2',3'-dideoxyadenosine triphosphate, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
6H58	Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... 著者 Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, D.N. 登録日 2018-07-24 公開日 2018-09-05 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1. Nat Microbiol, 3, 2018
6W1S	Atomic model of the mammalian Mediator complex 分子名称: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, Mediator of RNA polymerase II transcription subunit 11, ... 著者 Zhao, H, Young, N, Asturias, F. 登録日 2020-03-04 公開日 2021-03-10 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers. Cell, 178, 2019
4G7O	Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.993 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
4XJN	Structure of the parainfluenza virus 5 nucleocapsid-RNA complex: an insight into paramyxovirus polymerase activity 分子名称: LEAD (II) ION, Nucleocapsid, RNA (78-MER) 著者 Alayyoubi, M, Leser, G.P, Kors, C.A, Lamb, R.A. 登録日 2015-01-08 公開日 2015-03-18 最終更新日 2017-08-23 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Structure of the paramyxovirus parainfluenza virus 5 nucleoprotein-RNA complex. Proc.Natl.Acad.Sci.USA, 112, 2015
9F6J	Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state) 分子名称: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
7MLB	Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022
8PMP	Structure of the human nuclear cap-binding complex bound to ARS2[147-871] and m7GTP 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... 著者 Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. 登録日 2023-06-29 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
9F6L	Human DNA Polymerase epsilon bound to T-C mismatched DNA (Mismatch Excision state) 分子名称: CALCIUM ION, DNA nascent strand, DNA polymerase epsilon catalytic subunit A, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6K	Human DNA Polymerase epsilon bound to T-C mismatched DNA (Frayed Substrate state) 分子名称: DNA nascent strand, DNA polymerase epsilon catalytic subunit A, DNA template strand, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024
9F6I	Human DNA Polymerase epsilon bound to T-C mismatched DNA (Post-Insertion state) 分子名称: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA nascent strand, ... 著者 Roske, J.J, Yeeles, J.T.P. 登録日 2024-05-01 公開日 2024-08-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024

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