9F6E
Human DNA polymerase epsilon bound to DNA and PCNA (ajar conformation)
Summary for 9F6E
| Entry DOI | 10.2210/pdb9f6e/pdb |
| EMDB information | 50223 |
| Descriptor | DNA polymerase epsilon catalytic subunit A, Proliferating cell nuclear antigen, DNA nascent strand, ... (6 entities in total) |
| Functional Keywords | dna, polymerase, epsilon, pcna, leading strand, human, replication, replisome, proofreading |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 6 |
| Total formula weight | 244459.96 |
| Authors | Roske, J.J.,Yeeles, J.T.P. (deposition date: 2024-05-01, release date: 2024-08-07, Last modification date: 2024-08-21) |
| Primary citation | Roske, J.J.,Yeeles, J.T.P. Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol epsilon. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 39112807DOI: 10.1038/s41594-024-01370-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.74 Å) |
Structure validation
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