6Q9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6q9t by Molmil](/molmil-images/mine/6q9t) | Protein-aromatic foldamer complex crystal structure | 分子名称: | Aromatic foldamer, Carbonic anhydrase 2, ZINC ION | 著者 | Post, S, Langlois d'Estaintot, B, Fischer, L, Granier, T, Huc, I. | 登録日 | 2018-12-18 | 公開日 | 2019-09-18 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structure Elucidation of Helical Aromatic Foldamer-Protein Complexes with Large Contact Surface Areas. Chemistry, 25, 2019
|
|
6VKX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vkx by Molmil](/molmil-images/mine/6vkx) | Crystal structure of the carbohydrate-binding domain VP8* of human P[8] rotavirus strain BM13851 | 分子名称: | DI(HYDROXYETHYL)ETHER, Outer capsid protein VP4, TETRAETHYLENE GLYCOL | 著者 | Xu, S, McGinnis, K.R, Jiang, X, Kennedy, M.A. | 登録日 | 2020-01-22 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structural basis of P[II] rotavirus evolution and host ranges under selection of histo-blood group antigens. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6VJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vjc by Molmil](/molmil-images/mine/6vjc) | LmFPPS mutant T164Y in complex with 476A, IPP & Ca | 分子名称: | 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, ACETATE ION, CALCIUM ION, ... | 著者 | Maheshwari, S, Kim, Y.S, Aripirala, S, Gabelli, S.B. | 登録日 | 2020-01-15 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase. Biochemistry, 59, 2020
|
|
6QMQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qmq by Molmil](/molmil-images/mine/6qmq) | NF-YB/C Heterodimer in Complex with NF-YA-derived Peptide Stabilized with C8-Hydrocarbon Linker | 分子名称: | Nuclear transcription factor Y subunit alpha, Nuclear transcription factor Y subunit beta, Nuclear transcription factor Y subunit gamma, ... | 著者 | Kiehstaller, S, Jeganathan, S, Pearce, N.M, Wendt, M, Grossmann, T.N, Hennig, S. | 登録日 | 2019-02-08 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Constrained Peptides with Fine-Tuned Flexibility Inhibit NF-Y Transcription Factor Assembly. Angew.Chem.Int.Ed.Engl., 58, 2019
|
|
4J5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j5b by Molmil](/molmil-images/mine/4j5b) | Human Cyclophilin D Complexed with an Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-(2-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-2-oxoethyl)urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gelin, M, Colliandre, L, Bessin, Y, Guichou, J.F. | 登録日 | 2013-02-08 | 公開日 | 2014-02-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities. Nat Commun, 7, 2016
|
|
6QQ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qq8 by Molmil](/molmil-images/mine/6qq8) | |
3HR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hr4 by Molmil](/molmil-images/mine/3hr4) | Human iNOS Reductase and Calmodulin Complex | 分子名称: | CALCIUM ION, Calmodulin, FLAVIN MONONUCLEOTIDE, ... | 著者 | Xia, C, Misra, I, Iyanaki, T, Kim, J.J.K. | 登録日 | 2009-06-08 | 公開日 | 2009-09-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase J.Biol.Chem., 2009
|
|
3JTS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jts by Molmil](/molmil-images/mine/3jts) | GY9-Mamu-A*02-hb2m | 分子名称: | Beta-2-microglobulin, MHC class I Mamu-A*02, peptide of Gag-Pol polyprotein | 著者 | Dai, L, Feng, Y, Qi, J, Gao, G.F. | 登録日 | 2009-09-14 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structure of Mamu A*2 To be Published
|
|
6TH1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6th1 by Molmil](/molmil-images/mine/6th1) | IE1 from rat cytomegalovirus | 分子名称: | Immediate early protein 1 | 著者 | Schweininger, J, Muller, Y.A. | 登録日 | 2019-11-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers. Plos Pathog., 17, 2021
|
|
6T4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t4w by Molmil](/molmil-images/mine/6t4w) | ROR(gamma)t ligand binding domain in complex with 20-alpha-hydroxycholesterol and allosteric ligand Glenmark | 分子名称: | (3alpha,8alpha)-cholest-5-ene-3,20-diol, 4-[1-[2,6-bis(chloranyl)phenyl]carbonyl-5-methyl-thieno[3,2-c]pyrazol-3-yl]benzoic acid, GLYCEROL, ... | 著者 | de Vries, R.M.J.M, Meijer, F.A, Brunsveld, L. | 登録日 | 2019-10-15 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Cooperativity between the orthosteric and allosteric ligand binding sites of ROR gamma t. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
3JZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jzr by Molmil](/molmil-images/mine/3jzr) | |
6T3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t3j by Molmil](/molmil-images/mine/6t3j) | Dual Epitope Targeting by Anti-DR5 Antibodies | 分子名称: | IgG1-hDR5-01-Heavy Chain, IgG1-hDR5-01-Light Chain, IgG1-hDR5-05-Heavy Chain, ... | 著者 | Tauchert, M.J, Augustin, M, Krapp, S, Overdijk, M.B, Breij, E.C.W, Hibbert, R.G. | 登録日 | 2019-10-11 | 公開日 | 2020-09-16 | 最終更新日 | 2020-10-14 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Dual Epitope Targeting and Enhanced Hexamerization by DR5 Antibodies as a Novel Approach to Induce Potent Antitumor Activity Through DR5 Agonism. Mol.Cancer Ther., 19, 2020
|
|
3X3M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3x3m by Molmil](/molmil-images/mine/3x3m) | Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P212121 | 分子名称: | CALCIUM ION, ESX-1 secretion system protein EccB1 | 著者 | Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C. | 登録日 | 2015-01-24 | 公開日 | 2015-12-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase. Faseb J., 29, 2015
|
|
3K7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3k7j by Molmil](/molmil-images/mine/3k7j) | Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain | 分子名称: | CARBONATE ION, Indian hedgehog protein, SULFATE ION, ... | 著者 | He, Y.-X, Kang, Y, Zhang, W.J, Yu, J, Ma, G, Zhou, C.-Z. | 登録日 | 2009-10-13 | 公開日 | 2011-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the D100E mutant of the Indian Hedgehog N-terminal signalling domain To be Published
|
|
6TFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tfn by Molmil](/molmil-images/mine/6tfn) | |
3DUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3dur by Molmil](/molmil-images/mine/3dur) | Crystal structure of SAG173-04 | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... | 著者 | Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. | 登録日 | 2008-07-17 | 公開日 | 2008-12-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments. Acta Crystallogr.,Sect.D, 64, 2008
|
|
4LU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lu1 by Molmil](/molmil-images/mine/4lu1) | Crystal structure of the uncharacterized Maf protein YceF from E. coli, mutant D69A | 分子名称: | Maf-like protein YceF, UNKNOWN ATOM OR ION | 著者 | Dong, A, Xu, X, Cui, H, Tchigvintsev, A, Flick, R, Brown, G, Popovic, A, Yakunin, A.F, Savchenko, A, Structural Genomics Consortium (SGC) | 登録日 | 2013-07-24 | 公開日 | 2013-08-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Biochemical and structural studies of conserved maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides. Chem.Biol., 20, 2013
|
|
5T26
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5t26 by Molmil](/molmil-images/mine/5t26) | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. | 分子名称: | 4-hydroxy-tetrahydrodipicolinate synthase, GLYCEROL, L(+)-TARTARIC ACID, ... | 著者 | Chooback, L, Thomas, L.M, Karsten, W.E, Fleming, C.D, Seabourn, P. | 登録日 | 2016-08-23 | 公開日 | 2016-10-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Kinetic, Spectral and Structural Characterization of the Slow Binding Inhibitor Acetopyruvate with Dihydrodipicolinate Synthase from Escherichia coli. To Be Published
|
|
6TLB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tlb by Molmil](/molmil-images/mine/6tlb) | Plasmodium falciparum lipocalin (PF3D7_0925900) | 分子名称: | GLYCEROL, SODIUM ION, Serine/threonine protein kinase | 著者 | Burda, P.C, Crosskey, T.D, Lauk, K, Wilmanns, M, Gilberger, T.W. | 登録日 | 2019-12-02 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | SOLUTION SCATTERING (2.85 Å), X-RAY DIFFRACTION | 主引用文献 | Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum. Cell Rep, 31, 2020
|
|
6VWI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vwi by Molmil](/molmil-images/mine/6vwi) | Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | 著者 | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | 登録日 | 2020-02-19 | 公開日 | 2020-05-13 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
|
|
6R78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r78 by Molmil](/molmil-images/mine/6r78) | Structure of IMP-13 metallo-beta-lactamase in apo form (loop closed) | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Beta-lactamase, ... | 著者 | Zak, K.M, Softley, C, Kolonko, M, Sattler, M, Popowicz, G.M. | 登録日 | 2019-03-28 | 公開日 | 2020-04-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structure and Molecular Recognition Mechanism of IMP-13 Metallo-beta-Lactamase. Antimicrob.Agents Chemother., 64, 2020
|
|
6RCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rcv by Molmil](/molmil-images/mine/6rcv) | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | 分子名称: | R5.011 heavy chain, R5.011 light chain, R5.016 heavy chain, ... | 著者 | Alanine, D.W.G, Draper, S.J, Higgins, M.K. | 登録日 | 2019-04-11 | 公開日 | 2019-06-26 | 最終更新日 | 2019-07-10 | 実験手法 | X-RAY DIFFRACTION (3.582 Å) | 主引用文献 | Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies. Cell, 178, 2019
|
|
3HWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hwt by Molmil](/molmil-images/mine/3hwt) | Ternary complex of DNA polymerase lambda bound to a two nucleotide gapped DNA substrate with a scrunched dA | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*AP*GP*TP*AP*(2DT))-3', ... | 著者 | Garcia-Diaz, M, Bebenek, K, Larrea, A.A, Pedersen, L.C, Kunkel, T.A. | 登録日 | 2009-06-18 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Scrunching during DNA repair synthesis To be Published
|
|
3DUU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3duu by Molmil](/molmil-images/mine/3duu) | Crystal structure of SAG506-01, orthorhombic, twinned, crystal 2 | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... | 著者 | Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. | 登録日 | 2008-07-17 | 公開日 | 2008-12-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments. Acta Crystallogr.,Sect.D, 64, 2008
|
|
4DI1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4di1 by Molmil](/molmil-images/mine/4di1) | |