PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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3VZQ	Crystal structure of Q47L mutant of PhaB from Ralstonia eutropha 分子名称: Acetoacetyl-CoA reductase 著者 Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. 登録日 2012-10-15 公開日 2013-08-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics Appl.Environ.Microbiol., 79, 2013
4MB9	Structure of Streptococcus pneumonia ParE in complex with AZ13102335 分子名称: 1-ethyl-3-{6-(pyrimidin-5-yl)-5-[(3R)-tetrahydrofuran-3-ylmethoxy][1,3]thiazolo[5,4-b]pyridin-2-yl}urea, DNA topoisomerase IV, B subunit, ... 著者 Ogg, D, Tucker, J. 登録日 2013-08-19 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. J.Med.Chem., 56, 2013
4MBC	Structure of Streptococcus pneumonia ParE in complex with AZ13053807 分子名称: 1-{5-[2-(morpholin-4-yl)ethoxy]-6-(pyridin-3-yl)[1,3]thiazolo[5,4-b]pyridin-2-yl}-3-prop-2-en-1-ylurea, DNA topoisomerase IV, B subunit 著者 Ogg, D, Tucker, J. 登録日 2013-08-19 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. J.Med.Chem., 56, 2013
6S9A	Artificial GTPase-BSE dimer of human Dynamin1 分子名称: CHLORIDE ION, Dynamin-1,Dynamin-1, ZINC ION 著者 Ganichkin, O.M, Vancraenenbroeck, R, Rosenblum, G, Hofmann, H, Daumke, O, Noel, J.K. 登録日 2019-07-11 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor. Proc.Natl.Acad.Sci.USA, 118, 2021
3IMX	Crystal Structure of human glucokinase in complex with a synthetic activator 分子名称: (2R)-3-cyclopentyl-N-(5-methoxy[1,3]thiazolo[5,4-b]pyridin-2-yl)-2-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}propanamide, Glucokinase, SODIUM ION, ... 著者 Stams, T, Vash, B. 登録日 2009-08-11 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes. J.Med.Chem., 52, 2009
6VCG	Crystal structure of Nitrosotalea devanaterra carotenoid cleavage dioxygenase, cobalt form 分子名称: CHLORIDE ION, COBALT (II) ION, SODIUM ION, ... 著者 Daruwalla, A, Shi, W, Kiser, P.D. 登録日 2019-12-20 公開日 2020-07-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for carotenoid cleavage by an archaeal carotenoid dioxygenase. Proc.Natl.Acad.Sci.USA, 117, 2020
3IR1	Crystal Structure of Lipoprotein GNA1946 from Neisseria meningitidis 分子名称: METHIONINE, Outer membrane lipoprotein GNA1946, SULFATE ION 著者 Yang, X, Wu, Z, Wang, X, Shen, Y. 登録日 2009-08-21 公開日 2009-10-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of lipoprotein GNA1946 from Neisseria meningitidis J.Struct.Biol., 168, 2009
4IAK	Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBONATE ION, STRONTIUM ION, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-06 公開日 2013-06-12 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IAY	Room temperature X-ray Structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-07 公開日 2013-06-12 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
3VKO	Galectin-8 N-terminal domain in complex with sialyllactosamine 分子名称: CHLORIDE ION, Galectin-8, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Kamitori, S, Yoshida, H. 登録日 2011-11-18 公開日 2012-09-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 X-ray structure of a protease-resistant mutant form of human galectin-8 with two carbohydrate recognition domains Febs J., 279, 2012
3ICP	Crystal Structure of UDP-galactose 4-epimerase 分子名称: NAD-dependent epimerase/dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION 著者 Sakuraba, H, Kawai, T, Yoneda, K, Ohshima, T. 登録日 2009-07-18 公開日 2010-07-21 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal Structure of UDP-galactose 4-epimerase To be Published
6UR1	Crystal structure of ChoE S38A mutant in complex with acetate and acetylthiocholine 分子名称: ACETATE ION, ACETYLTHIOCHOLINE, ChoE, ... 著者 Pham, V.D, Shi, R. 登録日 2019-10-21 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism. J.Biol.Chem., 295, 2020
3FD5	Crystal structure of human selenophosphate synthetase 1 complex with AMPCP 分子名称: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Wang, K.T. 登録日 2008-11-25 公開日 2009-09-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of catalytic intermediates of human selenophosphate synthetase 1. J.Mol.Biol., 390, 2009
3FK0	E. coli EPSP synthase (TIPS mutation) liganded with S3P 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE 著者 Schonbrunn, E. 登録日 2008-12-15 公開日 2009-02-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
4I1N	R104A-ca1697 nanobody binding to the binary DHFR.folate complex 分子名称: Dihydrofolate reductase, FOLIC ACID, Protein ca1697 (nanobody) 著者 Oyen, D, Steyaert, J, Barlow, J.N. 登録日 2012-11-21 公開日 2013-11-27 実験手法 X-RAY DIFFRACTION (1.888 Å) 主引用文献 Exploring an alternative antibody interaction mechanism To be Published
6UY0	Cryo-EM structure of wild-type bovine multidrug resistance protein 1 (MRP1) under active turnover conditions 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ... 著者 Johnson, Z.L, Chen, J. 登録日 2019-11-09 公開日 2020-06-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses. Elife, 9, 2020
3FOR	Thermolysin Complexed with BNPA (2-Benzyl-3-Nitro Propanoic Acid Amide) 分子名称: (2R)-2-benzyl-3-nitropropanamide, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Wang, S.-F, Jin, J.-Y, Tian, G.-R. 登録日 2008-12-31 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Nitro as ZBG in the inhibition of Thermolysin To be Published
3IF1	Crystal structure of 237mAb in complex with a GalNAc 分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, Immunoglobulin heavy chain (IgG2a), Immunoglobulin light chain (IgG2a), ... 著者 Brooks, C.L, Evans, S.V, Borisova, S.N. 登録日 2009-07-23 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Antibody recognition of a unique tumor-specific glycopeptide antigen. Proc.Natl.Acad.Sci.USA, 107, 2010
4DME	GCN4 leucine zipper domain in a trimeric oligomerization state 分子名称: GCN4-p1 leucine zipper domain, SULFATE ION 著者 Oshaben, K.M, Salari, R, Chong, L.T, Horne, W.S. 登録日 2012-02-07 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Native GCN4 Leucine-Zipper Domain Does Not Uniquely Specify a Dimeric Oligomerization State. Biochemistry, 51, 2012
4IAF	Room temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-06 公開日 2013-06-12 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
5O87	Crystal structure of wild type Aplysia californica AChBP in complex with nicotine 分子名称: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Dawson, A, Hunter, W.N, de Souza, J.O, Trumper, P. 登録日 2017-06-12 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein. Iucrj, 6, 2019
3VWP	Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/R187S/H266N/D370Y mutant complexd with 6-aminohexanoate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ... 著者 Kawashima, Y, Shibata, N, Negoro, S, Higuchi, Y. 登録日 2012-08-30 公開日 2013-10-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural, kinetic and theoretical analyses of hydrolase mutants altering in the directionality and equilibrium point of reversible amide-synthetic/hydrolytic reaction to be published
4HJK	U7Ub7 Disulfide variant 分子名称: PHOSPHATE ION, Ubiquitin 著者 Murray, J.M, Rouge, L. 登録日 2012-10-12 公開日 2012-11-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.784 Å) 主引用文献 Potent and selective inhibitors of USP7/HAUSP activity by protein conformational stabilization to be published
6SMY	Crystal structure of SLA Reductase YihU from E. Coli with NADH and product DHPS 分子名称: (2~{S})-2,3-bis(oxidanyl)propane-1-sulfonic acid, 3-sulfolactaldehyde reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Sharma, M, Davies, G.J. 登録日 2019-08-23 公開日 2020-08-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Dynamic Structural Changes Accompany the Production of Dihydroxypropanesulfonate by Sulfolactaldehyde Reductase Acs Catalysis, 2020
6SES	Tubulin-B2 complex 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Guo, B, Rodriguez-Gabin, A, Prota, A.E, Muehlethaler, T, Zhang, N, Ye, K, Steinmetz, M.O, Band Horwitz, S, Smith III, A.B, McDaid, H.M. 登録日 2019-07-30 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence. Mol.Pharmacol., 98, 2020

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