PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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1B76	GLYCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glycine--tRNA ligase 著者 Arnez, J.G, Moras, D. 登録日 1999-01-27 公開日 1999-01-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine. J.Mol.Biol., 286, 1999
6NT5	Cryo-EM structure of full-length human STING in the apo state 分子名称: Stimulator of interferon protein 著者 Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. 登録日 2019-01-28 公開日 2019-03-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567, 2019
8JWJ	PHD Finger Protein 7 (PHF7) in complex with UBE2D2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHD finger protein 7, ... 著者 Lee, H.S, Bang, I, Choi, H.-J. 登録日 2023-06-29 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Molecular basis for PHF7-mediated ubiquitination of histone H3. Genes Dev., 37, 2023
8JWU	PHD Finger Protein 7 (PHF7) fused to UBE2D2 via a (GSGG)3 linker 分子名称: PHD finger protein 7,Ubiquitin-conjugating enzyme E2 D2, ZINC ION 著者 Lee, H.S, Bang, I, Choi, H.-J. 登録日 2023-06-29 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.58 Å) 主引用文献 Molecular basis for PHF7-mediated ubiquitination of histone H3. Genes Dev., 37, 2023
7V9A	biogenesis module of human telomerase holoenzyme 分子名称: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... 著者 Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. 登録日 2021-08-24 公開日 2022-03-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.94 Å) 主引用文献 Zipper head mechanism of telomere synthesis by human telomerase. Cell Res., 31, 2021
8OUE	The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation 分子名称: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... 著者 Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. 登録日 2023-04-22 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein. Nat Commun, 15, 2024
8OUF	The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open conformation 分子名称: H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... 著者 Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. 登録日 2023-04-22 公開日 2024-01-31 最終更新日 2024-02-07 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein. Nat Commun, 15, 2024
3IVB	Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1 分子名称: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ... 著者 Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S. 登録日 2009-08-31 公開日 2009-10-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure 9 To be Published
8JIG	A Novel UHRF1-Targeted Compound 分子名称: E3 ubiquitin-protein ligase UHRF1, N-[2,4-bis(oxidanylidene)-1H-pyrimidin-5-yl]-N'-oxidanyl-octanediamide 著者 Chen, Y, Jiang, L. 登録日 2023-05-26 公開日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A Novel UHRF1-Targeted Compound To Be Published
6ZQA	Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state A (Poly-Ala) 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2020-07-09 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
6ZQC	Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2020-07-09 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
6ZQB	Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state B2 分子名称: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... 著者 Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. 登録日 2020-07-09 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
4JFA	Crystal Structure of Plasmodium falciparum Tryptophanyl-tRNA synthetase 分子名称: BETA-MERCAPTOETHANOL, POTASSIUM ION, TRYPTOPHAN, ... 著者 Khan, S, Garg, A, Manickam, Y, Sharma, A. 登録日 2013-02-28 公開日 2014-01-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 An appended domain results in an unusual architecture for malaria parasite tryptophanyl-tRNA synthetase Plos One, 8, 2013
2A0C	Human CDK2 in complex with olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor 分子名称: 2-{[(2-{[(1R)-1-(HYDROXYMETHYL)PROPYL]AMINO}-9-ISOPROPYL-9H-PURIN-6-YL)AMINO]METHYL}PHENOL, Cell division protein kinase 2 著者 Krystof, V, McNae, I.W, Walkinshaw, M.D, Fischer, P.M, Muller, P, Vojtesek, B, Orsag, M, Havlicek, L, Strnad, M. 登録日 2005-06-16 公開日 2006-01-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor Cell.Mol.Life Sci., 62, 2005
6CHD	Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine 分子名称: 1,2-ETHANEDIOL, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, GLYCEROL, ... 著者 Dranow, D.M, Abendroth, J, Lorimer, D.D. 登録日 2018-02-22 公開日 2018-03-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine to be published
5IHX	Crystal Structure of a C-terminally truncated Aspergillus nidulans mitochondrial tyrosyl-tRNA synthetase 分子名称: TYROSINE, Tyrosine--tRNA ligase, mitochondrial 著者 Lamech, L.T, Lambowitz, A.M. 登録日 2016-02-29 公開日 2016-04-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Crystal Structure of a C-terminally truncated Aspergillus nidulans mitochondrial tyrosyl-tRNA synthetase To be published
5DZD	Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide 分子名称: E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION 著者 Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2015-09-25 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide To be Published
8IK3	Structure of Stimulator of interferon genes/ligand complex 分子名称: Stimulator of interferon genes protein,Immune protein Tsi3, cGAMP 著者 Lu, D.F, Shang, G.J. 登録日 2023-02-28 公開日 2023-05-17 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 The mechanism of STING autoinhibition and activation. Mol.Cell, 83, 2023
1JAT	Mms2/Ubc13 Ubiquitin Conjugating Enzyme Complex 分子名称: Ubiquitin-Conjugating Enzyme E2-17.5 KDA, Ubiquitin-Conjugating Enzyme Variant Mms2 著者 VanDemark, A.P, Hofmann, R.M, Tsui, C, Pickart, C.M, Wolberger, C. 登録日 2001-05-31 公開日 2001-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubc13 heterodimer. Cell(Cambridge,Mass.), 105, 2001
8JWS	ePHD domain of PHD Finger Protein 7 (PHF7) 分子名称: 1,2-ETHANEDIOL, PHD finger protein 7, ZINC ION 著者 Bang, I, Lee, H.S, Choi, H.-J. 登録日 2023-06-29 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for PHF7-mediated ubiquitination of histone H3. Genes Dev., 37, 2023
4N2P	Structure of Archease from Pyrococcus horikoshii 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Desai, K.K, Bingman, C.A, Phillips Jr, G.N, Raines, R.T. 登録日 2013-10-05 公開日 2014-01-01 最終更新日 2020-09-23 実験手法 X-RAY DIFFRACTION (1.435 Å) 主引用文献 A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation. Nucleic Acids Res., 42, 2014
8SEB	Cryo-EM structure of a single loaded human UBA7-UBE2L6-ISG15 adenylate complex 分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... 著者 Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. 登録日 2023-04-08 公開日 2023-10-11 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer. Nat Commun, 14, 2023
8SE9	Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex (Form 2) 分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... 著者 Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. 登録日 2023-04-08 公開日 2023-10-11 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer. Nat Commun, 14, 2023
8SEA	Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex (Form 1) 分子名称: ADENOSINE MONOPHOSPHATE, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-like protein ISG15, ... 著者 Afsar, M, Jia, L, Ruben, E.A, Olsen, S.K. 登録日 2023-04-08 公開日 2023-10-11 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer. Nat Commun, 14, 2023
6CYO	Crystal structure of human UBE2A (RAD6A) 分子名称: Ubiquitin-conjugating enzyme E2 A 著者 Ranzani, A.T, de Oliveira, J.F. 登録日 2018-04-06 公開日 2018-12-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Mechanistic insights revealed by a UBE2A mutation linked to intellectual disability. Nat. Chem. Biol., 15, 2019

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