PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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5WNQ	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus 分子名称: 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 DeMirci, H. 登録日 2017-08-01 公開日 2018-02-21 最終更新日 2020-10-21 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
7B5Z	Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 6 分子名称: 2-(1H-benzo[d][1,2,3]triazol-1-yl)-1-(4-methylenepiperidin-1-yl)ethan-1-one, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE 著者 Talibov, V.O. 登録日 2020-12-07 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
7AU4	Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 3 分子名称: (3~{S})-6-chloranyl-3'-(1,2-oxazol-3-ylmethyl)spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE 著者 Talibov, V.O. 登録日 2020-11-02 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
7B2J	Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 5 分子名称: 2-(1H-1,2,3-benzotriazol-1-yl)-1-(4-methylpiperidin-1-yl)ethan-1-one, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, ... 著者 Talibov, V.O. 登録日 2020-11-27 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
1O66	Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase 分子名称: 3-methyl-2-oxobutanoate hydroxymethyltransferase, GLYCEROL 著者 Structural GenomiX 登録日 2003-10-23 公開日 2003-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
4X5X	HLA-DR1 mutant bN82A with covalently linked CLIP106-120(M107W) 分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain 著者 Guenther, S, Freund, C. 登録日 2014-12-06 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.199 Å) 主引用文献 MHC class II complexes sample intermediate states along the peptide exchange pathway. Nat Commun, 7, 2016
4X64	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D. 登録日 2014-12-06 公開日 2015-11-18 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat.Struct.Mol.Biol., 23, 2016
5WE4	70S ribosome-EF-Tu wt complex with GppNHp 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Brown, Z, Frank, J. 登録日 2017-07-07 公開日 2018-04-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
4WSN	Crystal structure of the COP9 signalosome, a P1 crystal form 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Bunker, R.D, Lingaraju, G.M, Thoma, N.H. 登録日 2014-10-28 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome. Nature, 531, 2016
4WTW	Crystal structure of the third FnIII domain of integrin beta4 分子名称: 1,2-ETHANEDIOL, Integrin beta-4, PENTAETHYLENE GLYCOL, ... 著者 Alonso-Garcia, N, Urien, H, de Pereda, J.M. 登録日 2014-10-30 公開日 2015-02-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.606 Å) 主引用文献 Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin alpha6beta4 Acta Crystallogr.,Sect.D, 71, 2015
8BAH	Human Mre11-Nbs1 complex 分子名称: Double-strand break repair protein MRE11, MANGANESE (II) ION, Nibrin 著者 Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. 登録日 2022-10-11 公開日 2023-01-11 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (4.13 Å) 主引用文献 Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
1O60	Crystal structure of KDO-8-phosphate synthase 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase 著者 Structural GenomiX 登録日 2003-10-23 公開日 2003-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
5W84	CRYSTAL STRUCTURE OF IRAK-4 WITH A 4,6-DIAMINONICOTINAMIDE INHIBITOR (COMPOUND NUMBER 4) 分子名称: 4-(benzylamino)-6-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]pyridine-3-carboxamide, Interleukin-1 receptor-associated kinase 4 著者 Sack, J.S. 登録日 2017-06-21 公開日 2017-10-11 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery and structure-based design of 4,6-diaminonicotinamides as potent and selective IRAK4 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
5WCH	Crystal structure of the catalytic domain of human USP9X 分子名称: Probable ubiquitin carboxyl-terminal hydrolase FAF-X, UNKNOWN ATOM OR ION, ZINC ION 著者 Dong, A, Zhang, Q, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) 登録日 2017-06-30 公開日 2018-07-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8BG9	Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta 分子名称: Amyloid-beta protein 40 著者 Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W. 登録日 2022-10-27 公開日 2023-01-18 最終更新日 2023-02-22 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Acta Neuropathol, 145, 2023
6Z5F	CRYSTAL STRUCTURE OF RAT PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE-1 (RPMFE1) COMPLEXED WITH 3-KETODECANOYL-COA AND OXIDISED NICOTINAMIDE ADENINE DINUCLEOTIDE 分子名称: 3-KETO-DECANOYL-COA, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Wierenga, R.K, Sridhar, S, Kiema, T.R. 登録日 2020-05-26 公開日 2020-12-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystallographic binding studies of rat peroxisomal multifunctional enzyme type 1 with 3-ketodecanoyl-CoA: capturing active and inactive states of its hydratase and dehydrogenase catalytic sites. Acta Crystallogr D Struct Biol, 76, 2020
8BVM	Cryo-EM structure of Hfq-Crc-rbsB translation repression complex 分子名称: Catabolite repression control protein, RNA-binding protein Hfq, rbsB mRNA 著者 Dendooven, T, Luisi, B.F. 登録日 2022-12-04 公開日 2023-01-25 最終更新日 2023-02-08 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Translational regulation by Hfq-Crc assemblies emerges from polymorphic ribonucleoprotein folding. Embo J., 42, 2023
8B7Y	Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Koller, T.O, Graf, M, Wilson, D.N. 登録日 2022-10-03 公開日 2023-01-25 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. J.Am.Chem.Soc., 145, 2023
8BG0	Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40 分子名称: Amyloid-beta precursor protein 著者 Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordber, A, Goedert, M, Scheres, S.H.W. 登録日 2022-10-27 公開日 2023-01-18 最終更新日 2023-02-22 実験手法 ELECTRON MICROSCOPY (1.9 Å) 主引用文献 Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Acta Neuropathol, 145, 2023
6ZL1	Crystal structure of human serum albumin in complex with the MCL-1 neutralizing Alphabody CMPX-383B 分子名称: Albumin, CMPX-383B 著者 Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. 登録日 2020-06-30 公開日 2021-04-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.272 Å) 主引用文献 Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Sci Adv, 7, 2021
5WDT	70S ribosome-EF-Tu H84A complex with GppNHp 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Brown, Z, Frank, J. 登録日 2017-07-06 公開日 2018-04-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
5WE6	70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fislage, M, Frank, J. 登録日 2017-07-07 公開日 2018-04-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
6ZIE	Crystal structure of MCL-1 in complex with a neutralizing Alphabody CMPX-383B 分子名称: CMPX-383B, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION 著者 Pannecoucke, E, Savvides, S.N, Desmet, J, Lasters, I. 登録日 2020-06-25 公開日 2021-04-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting. Sci Adv, 7, 2021
3JW6	Crystal structure of AcMNPV baculovirus polyhedra 分子名称: 1,2-ETHANEDIOL, Polyhedrin 著者 Coulibaly, F, Chiu, E, Metcalf, P. 登録日 2009-09-17 公開日 2009-12-08 最終更新日 2018-07-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses Proc.Natl.Acad.Sci.USA, 106, 2009
5WJT	Cryo-EM structure of B. subtilis flagellar filaments N226Y 分子名称: Flagellin 著者 Wang, F, Burrage, A.M, Kearns, D.B, Egelman, E.H. 登録日 2017-07-24 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017

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