4X5X
HLA-DR1 mutant bN82A with covalently linked CLIP106-120(M107W)
Summary for 4X5X
Entry DOI | 10.2210/pdb4x5x/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain (2 entities in total) |
Functional Keywords | mhc ii, immune system, self antigen, invariant chain, clip |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Single-pass type I membrane protein: P01903 P04229 |
Total number of polymer chains | 4 |
Total formula weight | 96230.23 |
Authors | Guenther, S.,Freund, C. (deposition date: 2014-12-06, release date: 2016-03-09, Last modification date: 2024-01-10) |
Primary citation | Wieczorek, M.,Sticht, J.,Stolzenberg, S.,Gunther, S.,Wehmeyer, C.,El Habre, Z.,Alvaro-Benito, M.,Noe, F.,Freund, C. MHC class II complexes sample intermediate states along the peptide exchange pathway. Nat Commun, 7:13224-13224, 2016 Cited by PubMed: 27827392DOI: 10.1038/ncomms13224 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.199 Å) |
Structure validation
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