8BAH

Human Mre11-Nbs1 complex

Summary for 8BAH

• Entry DOI: 10.2210/pdb8bah/pdb
• EMDB information: 15948
• Descriptor: Double-strand break repair protein MRE11, Nibrin, MANGANESE (II) ION (3 entities in total)
• Functional Keywords: dna repair, complex, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 253310.04

Authors

Bartho, J.D.,Rotheneder, M.,Stakyte, K.,Lammens, K.,Hopfner, K.P. (deposition date: 2022-10-11, release date: 2023-01-11, Last modification date: 2023-12-13)

• Primary citation: Rotheneder, M.,Stakyte, K.,van de Logt, E.,Bartho, J.D.,Lammens, K.,Fan, Y.,Alt, A.,Kessler, B.,Jung, C.,Roos, W.P.,Steigenberger, B.,Hopfner, K.P.; Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.; Mol.Cell, 83:167-185.e9, 2023; PubMed: 36577401; DOI: 10.1016/j.molcel.2022.12.003

Experimental method

ELECTRON MICROSCOPY (4.13 Å)