PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

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7T28	Structure of phage Bsp38 anti-Pycsar nuclease Apyc1 in apo state 分子名称: Putative metal-dependent hydrolase, ZINC ION 著者 Hobbs, S.J, Wein, T, Lu, A, Morehouse, B.R, Schnabel, J, Sorek, R, Kranzusch, P.J. 登録日 2021-12-03 公開日 2022-04-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. Nature, 605, 2022
4XMG	Crystal structure of nitrophorin 7 from Rhodnius prolixus at pH 7.8 complexed with imidazole 分子名称: IMIDAZOLE, Nitrophorin-7, PROTOPORPHYRIN IX CONTAINING FE 著者 Ogata, H. 登録日 2015-01-14 公開日 2015-07-29 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure and dynamics of the membrane attaching nitric oxide transporter nitrophorin 7. F1000Res, 4, 2015
8R6N	Crystal structure of Candida glabrata Bdf1 bromodomain 2 bound to a pyridoindole ligand 分子名称: 2-ethanoyl-~{N}-(4-morpholin-4-ylphenyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-carboxamide, Candida glabrata strain CBS138 chromosome C complete sequence 著者 Petosa, C, Wei, K, McKenna, C.E, Govin, J. 登録日 2023-11-22 公開日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection Advanced Science, 2024
5R16	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 21, DMSO-free 分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 著者 Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. 登録日 2020-02-12 公開日 2020-06-03 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
8RRN	Crystal structure of the SARS-CoV-2 S RBD in complex with pT1616 Fab 分子名称: Spike protein S1, pT1616 Fab heavy chain, pT1616 Fab light chain 著者 Hansen, G, Krey, T. 登録日 2024-01-23 公開日 2024-10-30 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation. J.Virol., 2024
5R1K	PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 35, DMSO-free 分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 著者 Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S. 登録日 2020-02-12 公開日 2020-06-03 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening. Structure, 28, 2020
8R6L	Crystal structure of Candida glabrata Bdf1 bromodomain 2 in the unbound state 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Candida glabrata strain CBS138 chromosome C complete sequence, ... 著者 Petosa, C, Wei, K, McKenna, C.E, Govin, J. 登録日 2023-11-22 公開日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection Advanced Science, 2024
7TA0	Human Ornithine Aminotransferase (hOAT) soaked with 5-aminovaleric acid 分子名称: 5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, Ornithine aminotransferase, mitochondrial, ... 著者 Butrin, A, Liu, D. 登録日 2021-12-20 公開日 2022-05-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
8R7T	Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Alisporivir (nonimmunosuppressive analogue of Cyclosporin) 分子名称: Alisporivir, Peptidyl-prolyl cis-trans isomerase 著者 Jimenez-Faraco, E, Hermoso, J.A. 登録日 2023-11-27 公開日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Evaluating the potential of non-immunosuppressive cyclosporin analogs for targeting Toxoplasma gondii cyclophilin: Insights from structural studies. Protein Sci., 33, 2024
7TBC	Crystal structure of Plasmepsin X from Plasmodium falciparum in complex with WM382 分子名称: (4R)-4-[(2E)-4,4-diethyl-2-imino-6-oxo-1,3-diazinan-1-yl]-N-[(4S)-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3,4-dihydro-2H-1-benzopyran-6-carboxamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Christensen, J.B, Hodder, A.N, Scally, S.W, Cowman, A.F. 登録日 2021-12-21 公開日 2022-05-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax. Structure, 30, 2022
8RZF	RNase W from Sulfolobus acidocaldarius 分子名称: MAGNESIUM ION, Probable ribonuclease FAU-1 著者 Vayssieres, M, Blaud, M, Leulliot, N. 登録日 2024-02-12 公開日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 RNase W, a conserved ribonuclease family with a novel active site. Nucleic Acids Res., 2024
7TBE	Crystal structure of Plasmepsin X from Plasmodium vivax in complex with WM4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[(R)-[(2E,4S)-2-imino-4-methyl-6-oxo-4-(propan-2-yl)-1,3-diazinan-1-yl](phenyl)methyl]-N-[(1S)-1-phenylethyl]benzamide, Plasmepsin X, ... 著者 Hodder, A.N, Christensen, J.B, Scally, S.W, Cowman, A.F. 登録日 2021-12-21 公開日 2022-05-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax. Structure, 30, 2022
8R40	Crystal structure of diabody CR57 in complex with rabies virus protein G domain III 分子名称: GLYCEROL, Glycoprotein, Homospecific Diabody CR57 著者 Kedari, A, Rissanen, I. 登録日 2023-11-10 公開日 2024-11-06 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into rabies virus neutralization revealed by an engineered antibody scaffold. Structure, 2024
8R6J	Crystal structure of Candida glabrata Bdf1 bromodomain 1 bound to a pyrazole ligand 分子名称: 2-methyl-~{N}-[[5-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl]pyrazole-3-carboxamide, Candida glabrata strain CBS138 chromosome C complete sequence, SULFATE ION 著者 Petosa, C, Wei, K, McKenna, C.E, Govin, J. 登録日 2023-11-22 公開日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors with Antifungal Potential against invasive Candida infection Advanced Science, 2024
5LF4	Human 20S proteasome complex with Delanzomib at 2.0 Angstrom 分子名称: CHLORIDE ION, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... 著者 Schrader, J, Henneberg, F, Mata, R, Tittmann, K, Schneider, T.R, Stark, H, Bourenkov, G, Chari, A. 登録日 2016-06-30 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design. Science, 353, 2016
5LGY	Lysine 120-acetylated P53 DNA binding domain in a complex with the BAX response element. 分子名称: Cellular tumor antigen p53, DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3'), ... 著者 Arbely, E, Vainer, R. 登録日 2016-07-08 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structural Basis for p53 Lys120-Acetylation-Dependent DNA-Binding Mode. J.Mol.Biol., 428, 2016
5LJD	Crystal structure of holo human CRBP1/K40L mutant 分子名称: RETINOL, Retinol-binding protein 1, SODIUM ION 著者 Zanotti, G, Vallese, F, Berni, R, Menozzi, I. 登録日 2016-07-18 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structural and molecular determinants affecting the interaction of retinol with human CRBP1. J. Struct. Biol., 197, 2017
7T7A	Crystal Structure of Human SHOC2: A Leucine-Rich Repeat Protein 分子名称: Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, NITRATE ION 著者 Hajian, B, Lemke, C, Kwon, J, Bian, Y, Fuller, C, Aguirre, J. 登録日 2021-12-14 公開日 2022-05-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Nature, 609, 2022
8RAL	CL3E peptide bound to the I-Ab murine MHC class II receptor 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CL3E peptide, ... 著者 Erausquin, E, Urdiciain, A, Serra, P, Santamaria, P, Lopez-Sagaseta, J. 登録日 2023-12-01 公開日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 CL3E peptide bound to the I-Ab murine MHC class II receptor To be published
4XLQ	Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11 base-paired) promoter 分子名称: DNA (26-MER), DNA (30-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-13 公開日 2015-09-23 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (4.6 Å) 主引用文献 Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
5LLH	Crystal structure of human carbonic anhydrase isozyme II with 4-(1,3-Benzothiazol-2-ylthio)-2,3,5,6-tetrafluorobenzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(1,3-benzothiazol-2-ylsulfanyl)-2,3,5,6-tetrakis(fluoranyl)benzenesulfonamide, BICINE, ... 著者 Manakova, E, Smirnov, A, Grazulis, S. 登録日 2016-07-27 公開日 2017-08-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure correlations with the intrinsic thermodynamics of human carbonic anhydrase inhibitor binding. PeerJ, 6, 2018
8R84	pentameric IgMFc-AIM complex focused refinement 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CD5 antigen-like, ... 著者 Chen, Q, Arai, S, Miyazaki, T, Rosenthal, P. 登録日 2023-11-28 公開日 2024-11-06 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M. Nat Commun, 15, 2024
7T9Z	Human Ornithine Aminotransferase (hOAT) crystallized at pH 6.0 分子名称: Ornithine aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE 著者 Butrin, A, Liu, D. 登録日 2021-12-20 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
7TA1	Human Ornithine Aminotransferase (hOAT) soaked with gamma-Aminobutyric acid 分子名称: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, Ornithine aminotransferase, mitochondrial, ... 著者 Butrin, A, Wawrzak, Z, Liu, D. 登録日 2021-12-20 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. J.Biol.Chem., 298, 2022
8SQ8	X-ray crystal structure of Acinetobacter baumanii beta-lactamase variant OXA-109 in complex with doripenem 分子名称: (4R,5S)-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-3-({(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl}sulfanyl)-4,5-dihydro-1H-pyrrole-2-carboxylic acid, BICARBONATE ION, Beta-lactamase OXA-109 著者 Powers, R.A, Leonard, D.A, June, C.M, Szarecka, A, Wawrzak, Z. 登録日 2023-05-04 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural and Dynamic Features of Acinetobacter baumannii OXA-66 beta-Lactamase Explain Its Stability and Evolution of Novel Variants. J.Mol.Biol., 436, 2024

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