7T7A

Crystal Structure of Human SHOC2: A Leucine-Rich Repeat Protein

Summary for 7T7A

• Entry DOI: 10.2210/pdb7t7a/pdb
• Descriptor: Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, NITRATE ION, ... (4 entities in total)
• Functional Keywords: scaffold, leucine-rich, structural protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 111330.96

Authors

Hajian, B.,Lemke, C.,Kwon, J.,Bian, Y.,Fuller, C.,Aguirre, J. (deposition date: 2021-12-14, release date: 2022-05-04, Last modification date: 2024-05-22)

• Primary citation: Kwon, J.J.,Hajian, B.,Bian, Y.,Young, L.C.,Amor, A.J.,Fuller, J.R.,Fraley, C.V.,Sykes, A.M.,So, J.,Pan, J.,Baker, L.,Lee, S.J.,Wheeler, D.B.,Mayhew, D.L.,Persky, N.S.,Yang, X.,Root, D.E.,Barsotti, A.M.,Stamford, A.W.,Perry, C.K.,Burgin, A.,McCormick, F.,Lemke, C.T.,Hahn, W.C.,Aguirre, A.J.; Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex.; Nature, 609:408-415, 2022; PubMed: 35831509; DOI: 10.1038/s41586-022-04928-2

Experimental method

X-RAY DIFFRACTION (1.79 Å)