PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

---

7DB9	IC1 in complex with tubulin 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE, CALCIUM ION, ... 著者 Wu, C.Y, Wang, Y.X. 登録日 2020-10-19 公開日 2021-10-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.845 Å) 主引用文献 IC1 in complex with tubulin To Be Published
7D9L	Crystal structure of E. coli Grx2: Enzyme inhibited state in complex with Zinc and glutathione sulfinic acid 分子名称: CHLORIDE ION, Glutaredoxin, L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE, ... 著者 Sreekumar, S.N, Arockiasamy, A. 登録日 2020-10-13 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Crystal structure of E. coli Grx2: Enzyme inhibited state in complex with Zinc and glutathione sulfinic acid To Be Published
7DA8	X-ray structure of a GB1:T2Q/D46K mutant 分子名称: Immunoglobulin G-binding protein G 著者 Manjula, R, Ramaswamy, S, Gosavi, S. 登録日 2020-10-15 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 X-ray structure of a GB1:T2Q/D46K mutant To Be Published
7DBA	RYX in complex with tubulin 分子名称: 2-(1-methylindol-4-yl)-7-(3,4,5-trimethoxyphenyl)-1~{H}-benzimidazole, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Wu, C.Y, Wang, Y.X. 登録日 2020-10-19 公開日 2021-10-20 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.461 Å) 主引用文献 RYX in complex with tubulin To Be Published
7DOR	E. coli GyrB ATPase domain in complex with 4-nitropheno 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, P-NITROPHENOL, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-16 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DPR	E. coli GyrB ATPase domain in complex with methyl 3,4-dihydroxybenzoate 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-21 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
4GSC	Structure analysis of insulin degrading enzyme with compound bdm41559 ((s)-2-[2-(carboxymethyl-phenethyl-amino)-acetylamino]-3-(1h-imidazol-4-yl)-propionic acid methyl ester) 分子名称: Insulin-degrading enzyme, ZINC ION, methyl N-(carboxymethyl)-N-(2-phenylethyl)glycyl-L-histidinate 著者 Guo, Q, Deprez-Poulain, R, Deprez, B, Tang, W.J. 登録日 2012-08-27 公開日 2013-08-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis. Eur.J.Med.Chem., 79, 2014
4PVI	Crystal structure of GH62 hydrolase in complex with xylotriose 分子名称: GH62 hydrolase, PHOSPHATE ION, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose 著者 Nocek, B, Kaur, A.P, Xu, X, Cui, H, Savchenko, A. 登録日 2014-03-17 公開日 2014-09-24 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Crystal structure of GH62 hydrolase in complex with xylotriose TO BE PUBLISHED
7DE3	Human adenylate kinase 1 (hAK1) mutant-R128W 分子名称: Adenylate kinase isoenzyme 1 著者 Lin, W. 登録日 2020-11-01 公開日 2021-11-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.197 Å) 主引用文献 Structure of human adenylate kinase 1 mutant-R128W. To Be Published
7DG4	The co-crystal structure of DYRK2 with a small molecule inhibitor 6 分子名称: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-10 公開日 2021-11-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7SJ4	Human Trio residues 1284-1959 in complex with Rac1 分子名称: Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein 著者 Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G. 登録日 2021-10-15 公開日 2022-07-06 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1. J.Biol.Chem., 298, 2022
4GZO	N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with hepes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
4GZX	N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with human sialic acid receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
4GZS	N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
7DFJ	Crystal structure of glucose isomerase by serial millisecond crystallography 分子名称: MAGNESIUM ION, Xylose isomerase 著者 Nam, K.H. 登録日 2020-11-08 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of glucose isomerase by serial millisecond crystallography To Be Published
7DH3	The co-crystal structure of DYRK2 with a small molecule inhibitor 5 分子名称: 2,7-dimethoxy-9-piperidin-4-ylsulfanyl-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-12 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 The co-crystal structure of DYRK2 with a small molecule inhibitor 5 To Be Published
7DH9	The co-crystal structure of DYRK2 with a small molecule inhibitor 7 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridin-4-yl]methanol 著者 Wei, T, Xiao, J. 登録日 2020-11-13 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.194 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DFK	Crystal structure of xylitol-bound glucose isomerase by serial millisecond crystallography 分子名称: MAGNESIUM ION, Xylitol, Xylose isomerase 著者 Nam, K.H. 登録日 2020-11-08 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of xylitol-bound glucose isomerase by serial millisecond crystallography To Be Published
7DHC	The co-crystal structure of DYRK2 with a small molecule inhibitor 10 分子名称: 4-[bis(fluoranyl)methyl]-2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-13 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.592 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DG5	Crystal structure of mouse Smc1-Smc3 hinge domain containing a D574Y mutation 分子名称: Structural maintenance of chromosomes protein 1A, Structural maintenance of chromosomes protein 3 著者 Seo, H, Noh, H, Oh, B.-H. 登録日 2020-11-11 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Folding of cohesin's coiled coil is important for Scc2/4-induced association with chromosomes. Elife, 10, 2021
7DHH	The co-crystal structure of DYRK2 with a small molecule inhibitor 19 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [9-(azetidin-3-ylmethylsulfanyl)-2,7-dimethoxy-acridin-4-yl]methanol 著者 Wei, T, Xiao, J. 登録日 2020-11-14 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.486 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHO	The co-crystal structure of DYRK2 with a small molecule inhibitor 14 分子名称: 2-methoxy-9-(piperidin-4-ylmethylsulfanyl)-7-propan-2-yloxy-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-16 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHN	The co-crystal structure of DYRK2 with a small molecule inhibitor 20 分子名称: 7-methoxy-2-methylsulfanyl-9-(piperidin-4-ylmethylsulfanyl)-[1,3]thiazolo[5,4-b]quinoline, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-16 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHK	The co-crystal structure of DYRK2 with a small molecule inhibitor 13 分子名称: 2-methoxy-7-phenylmethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-16 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.341 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHV	The co-crystal structure of DYRK2 with a small molecule inhibitor 8 分子名称: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine-4-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-17 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.679 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022

<523524525526527528529530531532533534535536537538>