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8VFA
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Ternary DNA Polymerase Beta bound to DNA containing primer terminal dC base-paired with FapydG
分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*CP*(FAP)P*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ...
著者Oden, P.N, Ryan, B.J, Freudenthal, B.D.
登録日2023-12-21
公開日2024-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
8VFD
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BU of 8vfd by Molmil
Ternary DNA Polymerase Beta bound to DNA containing template FapydG incoming TTP analog
分子名称: 1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]-beta-D-threo-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione, DNA (5'-D(*CP*CP*GP*AP*CP*(FAP)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ...
著者Oden, P.N, Ryan, B.J, Freudenthal, B.D.
登録日2023-12-21
公開日2024-05-08
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Biochemical and structural characterization of Fapy•dG replication by Human DNA polymerase beta.
Nucleic Acids Res., 52, 2024
4L1U
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BU of 4l1u by Molmil
Crystal Structure of Human Rtf1 Plus3 Domain in Complex with Spt5 CTR Phosphopeptide
分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog, SULFATE ION, ...
著者Wier, A.D, Heroux, A, VanDemark, A.P.
登録日2013-06-03
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4L1P
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BU of 4l1p by Molmil
Crystal Structure of Human Rtf1 Plus3 domain
分子名称: GLYCEROL, RNA polymerase-associated protein RTF1 homolog
著者Wier, A.D, Heroux, A, VanDemark, A.P.
登録日2013-06-03
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural basis for Spt5-mediated recruitment of the Paf1 complex to chromatin.
Proc.Natl.Acad.Sci.USA, 110, 2013
4N5S
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BU of 4n5s by Molmil
Ternary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA and ddCTP
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-D(*AP*A*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', ...
著者Wu, E.Y.
登録日2013-10-10
公開日2015-01-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase.
Biochemistry, 54, 2015
2L41
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BU of 2l41 by Molmil
Nab3 RRM - UCUU complex
分子名称: RNA (5'-R(P*UP*CP*UP*U)-3'), RRM domain from Nuclear polyadenylated RNA-binding protein 3
著者Stefl, R, Pergoli, R, Hobor, F, Kubicek, K, Zimmermann, M, Pasulka, J, Hofr, C.
登録日2010-09-28
公開日2010-11-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein
J.Biol.Chem., 286, 2011
8B9K
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BU of 8b9k by Molmil
Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7modUUC, ...
著者Jagtap, P.K.A, Hennig, J.
登録日2022-10-06
公開日2023-10-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
Mol.Cell, 83, 2023
1O4X
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BU of 1o4x by Molmil
TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ...
著者Clore, G.M, Williams, D.C.
登録日2003-07-17
公開日2004-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004
3PKY
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BU of 3pky by Molmil
Polymerase Domain from Mycobacterium tuberculosis Ligase D in complex with DNA, UTP and Manganese.
分子名称: DNA 5'-D(*G*CP*CP*GP*CP*AP*AP*CP*GP*CP*AP*CP*G)-3', DNA 5'-D(P*GP*CP*GP*GP*C)-3', MANGANESE (II) ION, ...
著者Brissett, N.C, Fox, G.C, Pitcher, R.S, Doherty, A.J.
登録日2010-11-12
公開日2011-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of a Preternary Complex Involving a Prokaryotic NHEJ DNA Polymerase.
Mol.Cell, 41, 2011
4DQR
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BU of 4dqr by Molmil
Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
著者Wang, W, Beese, L.S.
登録日2012-02-16
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
1QFW
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BU of 1qfw by Molmil
TERNARY COMPLEX OF HUMAN CHORIONIC GONADOTROPIN WITH FV ANTI ALPHA SUBUNIT AND FV ANTI BETA SUBUNIT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (ANTI ALPHA SUBUNIT) (HEAVY CHAIN), ANTIBODY (ANTI ALPHA SUBUNIT) (LIGHT CHAIN), ...
著者Tegoni, M, Spinelli, S, Cambillau, C.
登録日1999-04-15
公開日2000-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.
J.Mol.Biol., 289, 1999
1HKN
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BU of 1hkn by Molmil
A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate
分子名称: 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1
著者Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A.
登録日2003-03-10
公開日2004-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
4K0R
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BU of 4k0r by Molmil
Crystal structure of mouse Cryptochrome 1
分子名称: Cryptochrome-1
著者Czarna, A, Wolf, E.
登録日2013-04-04
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function.
Cell(Cambridge,Mass.), 153, 2013
3QLM
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BU of 3qlm by Molmil
Crystal structure of porcine pancreatic phospholipase A2 in complex with n-hexadecanoic acid
分子名称: CALCIUM ION, PALMITIC ACID, Phospholipase A2, ...
著者Aparna, V, Dileep, K.V, Karthe, P, Mandal, P.K, Sadasivan, C, Haridas, M.
登録日2011-02-03
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Anti-inflammatory property of n-hexadecanoic acid: Structural evidence and Kinetic assessment.
Chem.Biol.Drug Des., 2012
6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
分子名称: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
著者Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
登録日2019-03-14
公開日2019-05-29
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
6ZTJ
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BU of 6ztj by Molmil
E. coli 70S-RNAP expressome complex in NusG-coupled state (38 nt intervening mRNA)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTL
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BU of 6ztl by Molmil
E. coli 70S-RNAP expressome complex in collided state bound to NusG
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTO
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BU of 6zto by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 1
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-20
公開日2020-09-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZU1
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BU of 6zu1 by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 2
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Webster, M.W, Takacs, M, Weixlbaumer, A.
登録日2020-07-21
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
7AAV
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BU of 7aav by Molmil
Human pre-Bact-2 spliceosome core structure
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-04
公開日2020-12-09
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
6DVC
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BU of 6dvc by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer
分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Lin, W, Das, K, Feng, Y, Ebright, R.H.
登録日2018-06-23
公開日2019-02-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
6DVB
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BU of 6dvb by Molmil
Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer
分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Lin, W, Das, K, Feng, Y, Ebright, R.H.
登録日2018-06-23
公開日2019-02-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of ECF-sigma-factor-dependent transcription initiation.
Nat Commun, 10, 2019
3T72
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BU of 3t72 by Molmil
PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex
分子名称: PHO BOX DNA (STRAND 1), PHO BOX DNA (STRAND 2), Phosphate regulon transcriptional regulatory protein phoB, ...
著者Blanco, A.G, Canals, A, Bernues, J, Sola, M, Coll, M.
登録日2011-07-29
公開日2011-09-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (4.33 Å)
主引用文献The structure of a transcription activation subcomplex reveals how sigma (70) is recruited to PhoB promoters.
Embo J., 30, 2011
1LV5
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BU of 1lv5 by Molmil
Crystal Structure of the Closed Conformation of Bacillus DNA Polymerase I Fragment Bound to DNA and dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*TP*CP*GP*CP*TP*GP*AP*TP*CP*CP*G)-3', 5'-D(*GP*GP*AP*TP*CP*AP*GP*CP*GP*A)-3', ...
著者Johnson, S.J, Taylor, J.S, Beese, L.S.
登録日2002-05-24
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA, 100, 2003
4DRW
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BU of 4drw by Molmil
Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide
分子名称: Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein
著者Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S.
登録日2012-02-17
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of an asymmetric ternary protein complex provides insight for membrane interaction.
Structure, 20, 2012

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