PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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6PB6	The E. coli class-II CAP-dependent transcription activation complex at the state 2 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.29 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
6PB5	The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Shi, W. 登録日 2019-06-13 公開日 2020-03-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Visualization of two architectures in class-II CAP-dependent transcription activation Plos Biol., 18, 2020
5ZX2	Mycobacterium tuberculosis RNA polymerase transcription initiation complex with ECF sigma factor sigma H and 7nt RNA 分子名称: DNA (47-MER), DNA (48-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2018-05-17 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for transcription initiation by bacterial ECF sigma factors. Nat Commun, 10, 2019
6KLE	Monomeric structure of Machupo virus polymerase bound to vRNA promoter 分子名称: MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... 著者 Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. 登録日 2019-07-30 公開日 2020-03-18 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural insight into arenavirus replication machinery. Nature, 579, 2020
6KLH	Dimeric structure of Machupo virus polymerase bound to vRNA promoter 分子名称: MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... 著者 Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. 登録日 2019-07-30 公開日 2020-03-18 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insight into arenavirus replication machinery. Nature, 579, 2020
6XZP	Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 分子名称: LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. 登録日 2020-02-05 公開日 2020-11-25 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6XZG	Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3 分子名称: Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ... 著者 Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. 登録日 2020-02-04 公開日 2020-11-25 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6XZR	Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 分子名称: LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. 登録日 2020-02-05 公開日 2020-11-25 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
6KLC	Structure of apo Lassa virus polymerase 分子名称: MANGANESE (II) ION, RNA-directed RNA polymerase L 著者 Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. 登録日 2019-07-30 公開日 2020-03-18 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural insight into arenavirus replication machinery. Nature, 579, 2020
6KLD	Structure of apo Machupo virus polymerase 分子名称: MANGANESE (II) ION, RNA-directed RNA polymerase L, ZINC ION 著者 Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. 登録日 2019-07-30 公開日 2020-03-18 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural insight into arenavirus replication machinery. Nature, 579, 2020
6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Lukarska, M, Cusack, S. 登録日 2018-01-14 公開日 2019-01-30 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
6FHH	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated. 分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Lukarska, M, Cusack, S. 登録日 2018-01-14 公開日 2019-01-30 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
6N62	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (3.803 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N61	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.253 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N60	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-23 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8PNT	Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... 著者 Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. 登録日 2023-07-01 公開日 2024-01-17 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
6N4C	EM structure of the DNA wrapping in bacterial open transcription initiation complex 分子名称: DNA (94-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Florez-Ariza, A, Cassago, A, de Oliveira, P.S.L, Guerra, D.G, Portugal, R.V. 登録日 2018-11-19 公開日 2020-05-27 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation Biorxiv, 2020
5N8X	Trigonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus 分子名称: 3D polymerase, GLYCEROL, MANGANESE (II) ION 著者 Ferrer-Orta, C, Verdaguer, N. 登録日 2017-02-24 公開日 2017-05-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus. Genome Biol Evol, 9, 2017
9F37	Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1 and +1 positions (strain A/little yellow-shouldered bat/Guatemala/060/2010/H17N10) 分子名称: 3' end of the vRNA promoter, 5' end of the vRNA promoter, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Cusack, S, Drncova, P. 登録日 2024-04-25 公開日 2024-09-18 実験手法 X-RAY DIFFRACTION (1.905 Å) 主引用文献 High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit Biorxiv, 2024
5M9Z	Second zinc-binding domain from yeast Pcf11 分子名称: Protein PCF11, ZINC ION 著者 Mackereth, C. 登録日 2016-11-02 公開日 2017-08-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Distinct roles of Pcf11 zinc-binding domains in pre-mRNA 3'-end processing. Nucleic Acids Res., 45, 2017
8PBL	E. coli RNA polymerase elongation complex stalled at thymine dimer lesion 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Woodgate, J, Zenkin, N. 登録日 2023-06-09 公開日 2023-10-25 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Translation selectively destroys non-functional transcription complexes. Nature, 626, 2024
1N35	lambda3 elongation complex with four phosphodiester bond formed 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*G)-3', ... 著者 Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. 登録日 2002-10-25 公開日 2002-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
7QXI	Cryo-EM structure of RNA polymerase-sigma54 holo enzyme with promoter DNA closed complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Ye, F.Z, Zhang, X.D. 登録日 2022-01-26 公開日 2022-11-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Mechanisms of DNA opening revealed in AAA+ transcription complex structures. Sci Adv, 8, 2022
6FLP	CryoEM structure of E.coli RNA polymerase paused elongation complex without RNA hairpin bound to NusA 分子名称: DNA (30-MER), DNA (39-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Guo, X, Weixlbaumer, A. 登録日 2018-01-26 公開日 2018-03-07 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural Basis for NusA Stabilized Transcriptional Pausing. Mol. Cell, 69, 2018
8FYH	G4 RNA-mediated PRC2 dimer 分子名称: G4 RNA, Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, ... 著者 Song, J, Kasinath, V. 登録日 2023-01-26 公開日 2023-10-04 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for inactivation of PRC2 by G-quadruplex RNA. Science, 381, 2023

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