3QCU
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![BU of 3qcu by Molmil](/molmil-images/mine/3qcu) | Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (14:0) | 分子名称: | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate, LT3015 antibody Fab fragment, heavy chain, ... | 著者 | Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T. | 登録日 | 2011-01-17 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | 主引用文献 | Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J.Mol.Biol., 408, 2011
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4NQ6
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![BU of 4nq6 by Molmil](/molmil-images/mine/4nq6) | Bacillus cereus Zn-dependent metallo-beta-lactamase at pH 7 complexed with compound L-CS319 | 分子名称: | (3S,5S,7aR)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid, Beta-lactamase 2, POTASSIUM ION, ... | 著者 | Gonzalez, J.M, Gonzalez, M.M, Vila, A.J. | 登録日 | 2013-11-23 | 公開日 | 2014-11-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cross-class metallo-beta-lactamase inhibition by bisthiazolidines reveals multiple binding modes. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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4NV4
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![BU of 4nv4 by Molmil](/molmil-images/mine/4nv4) | 1.8 Angstrom Crystal Structure of Signal Peptidase I from Bacillus anthracis. | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Signal peptidase I, ... | 著者 | Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Shatsman, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-12-04 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 1.8 Angstrom Crystal Structure of Signal Peptidase I from Bacillus anthracis. TO BE PUBLISHED
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1DMS
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![BU of 1dms by Molmil](/molmil-images/mine/1dms) | STRUCTURE OF DMSO REDUCTASE | 分子名称: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, DMSO REDUCTASE, MOLYBDENUM (IV)OXIDE | 著者 | Schneider, F, Loewe, J, Huber, R, Schindelin, H, Kisker, C, Knaeblein, J. | 登録日 | 1996-09-03 | 公開日 | 1998-07-01 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal structure of dimethyl sulfoxide reductase from Rhodobacter capsulatus at 1.88 A resolution. J.Mol.Biol., 263, 1996
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4CVU
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![BU of 4cvu by Molmil](/molmil-images/mine/4cvu) | Structure of Fungal beta-mannosidase from Glycoside Hydrolase Family 2 of Trichoderma harzianum | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-MANNOSIDASE, CADMIUM ION, ... | 著者 | Muniz, J.R.C, Aparicio, R, Santos, J.C, Nascimento, A.S, Golubev, A.M, Polikarpov, I. | 登録日 | 2014-03-31 | 公開日 | 2014-07-09 | 最終更新日 | 2023-07-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Insights into the structure and function of fungal beta-mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme. FEBS J., 281, 2014
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4F33
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![BU of 4f33 by Molmil](/molmil-images/mine/4f33) | Crystal Structure of therapeutic antibody MORAb-009 | 分子名称: | MORAb-009 FAB heavy chain, MORAb-009 FAB light chain, TETRAETHYLENE GLYCOL | 著者 | Xia, D, Ma, J, Tang, W.K, Esser, L. | 登録日 | 2012-05-08 | 公開日 | 2012-07-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | 主引用文献 | Recognition of mesothelin by the therapeutic antibody MORAb-009: structural and mechanistic insights. J.Biol.Chem., 287, 2012
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4F9Y
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![BU of 4f9y by Molmil](/molmil-images/mine/4f9y) | Human P38 alpha MAPK In Complex With a Novel and Selective Small Molecule Inhibitor | 分子名称: | 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | 登録日 | 2012-05-21 | 公開日 | 2013-06-05 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction. Plos One, 8, 2013
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5VQ1
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![BU of 5vq1 by Molmil](/molmil-images/mine/5vq1) | Crystal structure of human KRAS Q61A mutant in complex with GDP | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Xu, S, Long, B, Boris, G, Ni, S, Kennedy, M.A. | 登録日 | 2017-05-07 | 公開日 | 2017-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras. Acta Crystallogr D Struct Biol, 73, 2017
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5SVP
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![BU of 5svp by Molmil](/molmil-images/mine/5svp) | Anomalous sulfur signal reveals the position of agonist 2-methylthio-ATP bound to the ATP-gated human P2X3 ion channel in the desensitized state | 分子名称: | 1,2-ETHANEDIOL, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | 登録日 | 2016-08-07 | 公開日 | 2016-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.298 Å) | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538, 2016
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4F9W
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![BU of 4f9w by Molmil](/molmil-images/mine/4f9w) | Human P38alpha MAPK in Complex with a Novel and Selective Small Molecule Inhibitor | 分子名称: | 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, ACETATE ION, BETA-MERCAPTOETHANOL, ... | 著者 | Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | 登録日 | 2012-05-21 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction. Plos One, 8, 2013
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4R5F
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![BU of 4r5f by Molmil](/molmil-images/mine/4r5f) | X-ray structure of the D199K mutant of the cysteine desulfurase IscS from A. fulgidus | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ACETATE ION, CALCIUM ION, ... | 著者 | Pagnier, A, Nicolet, Y, Fontecilla-Camps, J.C. | 登録日 | 2014-08-21 | 公開日 | 2014-12-17 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | IscS from Archaeoglobus fulgidus has no desulfurase activity but may provide a cysteine ligand for [Fe2S2] cluster assembly. Biochim.Biophys.Acta, 1853, 2015
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2A5I
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![BU of 2a5i by Molmil](/molmil-images/mine/2a5i) | Crystal structures of SARS coronavirus main peptidase inhibited by an aza-peptide epoxide in the space group C2 | 分子名称: | (5S,8S,14R)-ETHYL 11-(3-AMINO-3-OXOPROPYL)-8-BENZYL-14-HYDROXY-5-ISOBUTYL-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,11-TETRAAZAPENTADECAN-15-OATE, 1,2-ETHANEDIOL, 3C-like peptidase, ... | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N. | 登録日 | 2005-06-30 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide J.Mol.Biol., 353, 2005
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4FA2
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![BU of 4fa2 by Molmil](/molmil-images/mine/4fa2) | Human P38 alpha Mitogen-Activated Kinase In Complex With SB239063 | 分子名称: | 1,2-ETHANEDIOL, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, BETA-MERCAPTOETHANOL, ... | 著者 | Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M. | 登録日 | 2012-05-21 | 公開日 | 2013-06-05 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction. Plos One, 8, 2013
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7YGL
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![BU of 7ygl by Molmil](/molmil-images/mine/7ygl) | |
4F5V
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![BU of 4f5v by Molmil](/molmil-images/mine/4f5v) | Crystal Structure of Leporine Serum Albumin | 分子名称: | ACETATE ION, Serum albumin, TETRAETHYLENE GLYCOL, ... | 著者 | Bujacz, A, Bujacz, G. | 登録日 | 2012-05-13 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structures of bovine, equine and leporine serum albumin. Acta Crystallogr.,Sect.D, 68, 2012
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5SVS
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![BU of 5svs by Molmil](/molmil-images/mine/5svs) | Anomalous Mn2+ signal reveals a divalent cation-binding site in the head domain of the ATP-gated human P2X3 ion channel | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | 登録日 | 2016-08-07 | 公開日 | 2016-09-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.025 Å) | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action. Nature, 538, 2016
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4BOW
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![BU of 4bow by Molmil](/molmil-images/mine/4bow) | Crystal structure of LamA_E269S from Z. galactanivorans in complex with laminaritriose and laminaritetraose | 分子名称: | CALCIUM ION, ENDO-1,3-BETA-GLUCANASE, FAMILY GH16, ... | 著者 | Labourel, A, Jeudy, A, Czjzek, M, Michel, G. | 登録日 | 2013-05-22 | 公開日 | 2013-12-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The Beta-Glucanase Zglama from Zobellia Galactanivorans Evolved a Bent Active Site Adapted for Efficient Degradation of Algal Laminarin J.Biol.Chem., 289, 2014
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5T37
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![BU of 5t37 by Molmil](/molmil-images/mine/5t37) | crystal structure of mPGES-1 bound to inhibitor | 分子名称: | 2-chloro-5-{[(2,2-dimethylpropanoyl)amino]methyl}-N-(1H-imidazol-2-yl)benzamide, GLUTATHIONE, Prostaglandin E synthase, ... | 著者 | Luz, J.G, Antonysamy, S, Partridge, K, Fisher, M. | 登録日 | 2016-08-24 | 公開日 | 2017-03-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.761 Å) | 主引用文献 | Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1. Bioorg. Med. Chem. Lett., 27, 2017
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2XWP
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![BU of 2xwp by Molmil](/molmil-images/mine/2xwp) | ANAEROBIC COBALT CHELATASE (CbiK) FROM SALMONELLA TYPHIMURIUM IN COMPLEX WITH METALATED TETRAPYRROLE | 分子名称: | COBALT SIROHYDROCHLORIN, GLYCEROL, SIROHYDROCHLORIN COBALTOCHELATASE | 著者 | Ladakis, D, Brindley, A.A, Deery, E, Warren, M.J, Pickersgill, R.W. | 登録日 | 2010-11-04 | 公開日 | 2010-12-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Evolution in a Family of Chelatases Facilitated by the Introduction of Active Site Asymmetry and Protein Oligomerization. Proc.Natl.Acad.Sci.USA, 108, 2011
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4CA6
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![BU of 4ca6 by Molmil](/molmil-images/mine/4ca6) | Human Angiotensin converting enzyme N-domain in complex with a phosphinic tripeptide FI | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANGIOTENSIN-CONVERTING ENZYME N-DOMAIN, CHLORIDE ION, ... | 著者 | Masuyer, G, Akif, M, Czarny, B, Beau, F, Schwager, S.L.U, Sturrock, E.D, Isaac, R.E, Dive, V, Acharya, K.R. | 登録日 | 2013-10-07 | 公開日 | 2013-12-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. FEBS J., 281, 2014
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5VTA
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![BU of 5vta by Molmil](/molmil-images/mine/5vta) | Co-Crystal Structure of DPPIV with a Chemibody Inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-{4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]piperazin-1-yl}-N-(22-oxo-3,6,9,12,15,18-hexaoxa-21-azatricosan-1-yl)acetamide, ... | 著者 | Wang, Z, Johnstone, S, Cheng, A. | 登録日 | 2017-05-16 | 公開日 | 2018-05-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-guided Discovery of Dual-recognition Chemibodies. Sci Rep, 8, 2018
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4RPC
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![BU of 4rpc by Molmil](/molmil-images/mine/4rpc) | Crystal structure of the putative alpha/beta hydrolase family protein from Desulfitobacterium hafniense | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TETRAETHYLENE GLYCOL, putative alpha/beta hydrolase | 著者 | Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-10-30 | 公開日 | 2014-11-12 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the putative alpha/beta hydrolase family protein from Desulfitobacterium hafniense To be Published
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5VW1
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![BU of 5vw1 by Molmil](/molmil-images/mine/5vw1) | |
1OQM
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![BU of 1oqm by Molmil](/molmil-images/mine/1oqm) | A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine | 分子名称: | Alpha-lactalbumin, CALCIUM ION, MANGANESE (II) ION, ... | 著者 | Ramakrishnan, B, Qasba, P.K. | 登録日 | 2003-03-10 | 公開日 | 2003-03-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient
N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity. J.Biol.Chem., 277, 2002
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3RN1
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![BU of 3rn1 by Molmil](/molmil-images/mine/3rn1) | |