5VTA

Co-Crystal Structure of DPPIV with a Chemibody Inhibitor

Summary for 5VTA

• Entry DOI: 10.2210/pdb5vta/pdb
• Related: 4FFV 4FFW
• Descriptor: Dipeptidyl peptidase 4, Fab light chain, Fab heavy chain, ... (9 entities in total)
• Functional Keywords: hydrolase, chemibody
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 12
• Total formula weight: 535923.46

Authors

Wang, Z.,Johnstone, S.,Cheng, A. (deposition date: 2017-05-16, release date: 2018-05-09, Last modification date: 2020-07-29)

• Primary citation: Cheng, A.C.,Doherty, E.M.,Johnstone, S.,DiMauro, E.F.,Dao, J.,Luthra, A.,Ye, J.,Tang, J.,Nixey, T.,Min, X.,Tagari, P.,Miranda, L.P.,Wang, Z.; Structure-guided Discovery of Dual-recognition Chemibodies.; Sci Rep, 8:7570-7570, 2018; PubMed: 29765112; DOI: 10.1038/s41598-018-25848-0

Experimental method

X-RAY DIFFRACTION (2.8 Å)