6E3K
 
 | | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Jude, K.M, Mendoza, J.L, Garcia, K.C. | | 登録日 | 2018-07-14 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
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6E3L
 | | Interferon gamma signalling complex with IFNGR1 and IFNGR2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, ... | | 著者 | Jude, K.M, Mendoza, J.L, Garcia, K.C. | | 登録日 | 2018-07-14 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of the IFN gamma receptor complex guides design of biased agonists.
Nature, 567, 2019
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8JO2
 | | Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA | | 分子名称: | DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P. | | 登録日 | 2023-06-06 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA.
Nucleic Acids Res., 51, 2023
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1XCV
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8F1I
 | | SigN RNA polymerase early-melted intermediate bound to mismatch fragment dhsU36mm1 (-12T) | | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | | 登録日 | 2022-11-05 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1J
 | | SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A) | | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | | 登録日 | 2022-11-05 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1K
 | | SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) | | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | | 登録日 | 2022-11-05 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7E0F
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7V4B
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7V4C
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7V47
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7V48
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7V4A
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7V4D
 | | Heparin-remodelled alpha-synuclein fibrils | | 分子名称: | Alpha-synuclein | | 著者 | Tao, Y.Q, Sun, Y.P, Xia, W.C, Zhao, Q.Y, Liu, C, Li, D. | | 登録日 | 2021-08-12 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Heparin-remodelled alpha-synuclein fibrils
To Be Published
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7V49
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7WMM
 | | alpha-synuclein fibril-F0502B complex | | 分子名称: | 2-bromanyl-4-[(~{E})-2-[6-[2-(2-fluoranylethoxy)ethyl-methyl-amino]-5-methyl-1,3-benzothiazol-2-yl]ethenyl]phenol, Alpha-synuclein | | 著者 | Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D. | | 登録日 | 2022-01-15 | | 公開日 | 2023-01-18 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | alpha-synuclein fibril-F0502B complex
To Be Published
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4LRK
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1EKU
 | | CRYSTAL STRUCTURE OF A BIOLOGICALLY ACTIVE SINGLE CHAIN MUTANT OF HUMAN IFN-GAMMA | | 分子名称: | Interferon gamma, SULFATE ION | | 著者 | Landar, A, Curry, B, Parker, M.H, DiGiacomo, R, Indelicato, S.R, Walter, M.R. | | 登録日 | 2000-03-09 | | 公開日 | 2000-09-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.
J.Mol.Biol., 299, 2000
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1LP9
 | | Xenoreactive complex AHIII 12.2 TCR bound to p1049/HLA-A2.1 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | 著者 | Buslepp, J, Wang, H, Biddison, W.E, Appella, E, Collins, E.J. | | 登録日 | 2002-05-07 | | 公開日 | 2003-11-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.
Immunity, 19, 2003
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1FG9
 | | 3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER | | 分子名称: | INTERFERON GAMMA, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN | | 著者 | Thiel, D.J, le Du, M.-H, Walter, R.L, D'Arcy, A, Chene, C, Fountoulakis, M, Garotta, G, Winkler, F.K, Ealick, S.E. | | 登録日 | 2000-07-28 | | 公開日 | 2000-08-11 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.
Structure Fold.Des., 8, 2000
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3VFZ
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6VCJ
 | | Crystal structure of hsDHFR in complex with NADP+, DAP, and R-naproxen | | 分子名称: | (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Dihydrofolate reductase, FOLIC ACID, ... | | 著者 | Pedersen, L.C, London, R.E, Gabel, S.A, Krahn, J.M, DeRose, E.F. | | 登録日 | 2019-12-21 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
J.Med.Chem., 63, 2020
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7DHP
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3ONM
 | | Effector binding Domain of LysR-Type transcription factor RovM from Y. pseudotuberculosis | | 分子名称: | Transcriptional regulator LrhA | | 著者 | Quade, N, Diekmann, M, Haffke, M, Heroven, A.K, Dersch, P, Heinz, D.W. | | 登録日 | 2010-08-30 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis.
Acta Crystallogr.,Sect.D, 67, 2011
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4LRJ
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