PDB: 186017 件ウェブページステータス検索Chemie searchBIRD

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6OQS	E. coli ATP synthase State 1b 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Stewart, A.G, Sobti, M, Walshe, J.L. 登録日 2019-04-29 公開日 2020-06-03 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
6OQT	E. coli ATP synthase State 1c 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Stewart, A.G, Sobti, M, Walshe, J.L. 登録日 2019-04-29 公開日 2020-06-03 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
6XZ2	Crystal structure of E. Coli purine nucleoside phosphorylase mutant Y160W with SO4 and Formycin A 分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Purine nucleoside phosphorylase DeoD-type, SULFATE ION 著者 Narczyk, M, Bzowska, A. 登録日 2020-01-31 公開日 2021-02-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.65000308 Å) 主引用文献 Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent. Sci Rep, 11, 2021
6P9S	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 7 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6P9Q	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 2 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6PQV	E. coli ATP Synthase State 1e 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Stewart, A.G, Sobti, M, Walshe, J.L. 登録日 2019-07-10 公開日 2020-06-03 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
6P9P	E.coli LpxA in complex with Compound 1 分子名称: 3-[2-(4-methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6OQU	E. coli ATP synthase State 1d 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Stewart, A.G, Sobti, M, Walshe, J.L. 登録日 2019-04-29 公開日 2020-06-03 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
6OQR	E. coli ATP Synthase ADP State 1a 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... 著者 Stewart, A.G, Walshe, J.L, Sobti, M. 登録日 2019-04-29 公開日 2020-06-03 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
6P9R	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 6 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6P9T	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 8 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
8C5P	E. coli NfsB mutant N71S T41L with acetate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Day, M.A, White, S.A, Hyde, E.I. 登録日 2023-01-10 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
8CCV	E. coli NfsB mutant T41LN71S with nicotinate 分子名称: FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Oxygen-insensitive NAD(P)H nitroreductase 著者 Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. 登録日 2023-01-27 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
8CJ0	E. coli NfsB-T41Q/N71S/F124T/M127V mutant bound to nicotinate 分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... 著者 White, S.A, Hyde, E.I, Day, M.A. 登録日 2023-02-11 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
8C5E	E. coli NfsB-T41Q/N71S/F124T mutant bound to nicotinic acid 分子名称: 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... 著者 White, S.A, Hyde, E.I, Day, M.A. 登録日 2023-01-06 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
8C5F	E. coli NfsB-T41Q/N71S/F124T mutant bound to acetate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, FLAVIN MONONUCLEOTIDE, ... 著者 White, S.A, Hyde, E.I, Day, M.A. 登録日 2023-01-07 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
8OG3	E. coli NfsB triple mutant T41L/N71S/F124T bound to citrate 分子名称: 1,2-ETHANEDIOL, CITRIC ACID, FLAVIN MONONUCLEOTIDE, ... 著者 Day, M.A, White, S.A, Hyde, E.I, Searle, P.F. 登録日 2023-03-17 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24, 2023
9C0D	E.Faecium GroEL 分子名称: Chaperonin GroEL 著者 Watson, E.R, Lander, G.C. 登録日 2024-05-25 公開日 2024-08-07 最終更新日 2024-08-14 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. J.Am.Chem.Soc., 146, 2024
9C0C	E.coli GroEL apoenzyme 分子名称: 60 kDa chaperonin 著者 Watson, E.R, Lander, G.C. 登録日 2024-05-25 公開日 2024-08-07 最終更新日 2024-08-14 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target. J.Am.Chem.Soc., 146, 2024
6RKS	E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 without TOPRIM insertion 分子名称: (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... 著者 Vanden Broeck, A, Lamour, V. 登録日 2019-04-30 公開日 2019-11-06 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
6RKV	E. coli DNA Gyrase - DNA binding and cleavage domain in State 2 分子名称: DNA Strand 1, DNA Strand 2, DNA gyrase subunit A, ... 著者 Vanden Broeck, A, Lamour, V. 登録日 2019-04-30 公開日 2019-11-06 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
6RKU	E. coli DNA Gyrase - DNA binding and cleavage domain in State 1 分子名称: (3~{R})-3-[[4-(3,4-dihydro-2~{H}-pyrano[2,3-c]pyridin-6-ylmethylamino)piperidin-1-yl]methyl]-1,4,7-triazatricyclo[6.3.1.0^{4,12}]dodeca-6,8(12),9-triene-5,11-dione, DNA Strand 1, DNA Strand 2, ... 著者 Vanden Broeck, A, Lamour, V. 登録日 2019-04-30 公開日 2019-11-06 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex. Nat Commun, 10, 2019
5JRD	E. coli Hydrogenase-1 variant P508A 分子名称: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, FE3-S4 CLUSTER, ... 著者 Carr, S.B, Phillips, S.E.V, Armstrong, F.A, Evans, R.M, Brooke, E.J, Islam, S.T.A. 登録日 2016-05-06 公開日 2017-03-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Importance of the Active Site "Canopy" Residues in an O2-Tolerant [NiFe]-Hydrogenase. Biochemistry, 56, 2017
7UO1	E.coli RNaseP Holoenzyme with Mg2+ 分子名称: CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ... 著者 Huang, W, Taylor, D.J. 登録日 2022-04-12 公開日 2022-09-28 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P. Nat Commun, 13, 2022
7TOS	E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. 登録日 2022-01-24 公開日 2022-05-25 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022

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