8CCV
E. coli NfsB mutant T41LN71S with nicotinate
Summary for 8CCV
Entry DOI | 10.2210/pdb8ccv/pdb |
Descriptor | Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... (4 entities in total) |
Functional Keywords | oxygen insensitve nad(p)h nitroreductase, double mutant, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 49003.32 |
Authors | Day, M.A.,White, S.A.,Hyde, E.I.,Searle, P.F. (deposition date: 2023-01-27, release date: 2023-04-19) |
Primary citation | Day, M.A.,Christofferson, A.J.,Anderson, J.L.R.,Vass, S.O.,Evans, A.,Searle, P.F.,White, S.A.,Hyde, E.I. Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 36983061DOI: 10.3390/ijms24065987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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