8C5F
E. coli NfsB-T41Q/N71S/F124T mutant bound to acetate
Summary for 8C5F
Entry DOI | 10.2210/pdb8c5f/pdb |
Descriptor | Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | nitroreductase mutant, complex, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 49165.24 |
Authors | White, S.A.,Hyde, E.I.,Day, M.A. (deposition date: 2023-01-07, release date: 2023-04-19, Last modification date: 2024-06-19) |
Primary citation | Day, M.A.,Christofferson, A.J.,Anderson, J.L.R.,Vass, S.O.,Evans, A.,Searle, P.F.,White, S.A.,Hyde, E.I. Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954. Int J Mol Sci, 24:-, 2023 Cited by PubMed: 36983061DOI: 10.3390/ijms24065987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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