8C5P

E. coli NfsB mutant N71S T41L with acetate

Summary for 8C5P

• Entry DOI: 10.2210/pdb8c5p/pdb
• Related: 8C5E 8C5F
• Descriptor: Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: oxygen insensitive nad(p)h nitroreductase, double mutant, oxidoreductase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 49400.84

Authors

Day, M.A.,White, S.A.,Hyde, E.I. (deposition date: 2023-01-10, release date: 2023-04-19)

• Primary citation: Day, M.A.,Christofferson, A.J.,Anderson, J.L.R.,Vass, S.O.,Evans, A.,Searle, P.F.,White, S.A.,Hyde, E.I.; Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.; Int J Mol Sci, 24:-, 2023; PubMed: 36983061; DOI: 10.3390/ijms24065987

Experimental method

X-RAY DIFFRACTION (1.69 Å)