6XZ2

Crystal structure of E. Coli purine nucleoside phosphorylase mutant Y160W with SO4 and Formycin A

Summary for 6XZ2

Entry DOI	10.2210/pdb6xz2/pdb
Descriptor	Purine nucleoside phosphorylase DeoD-type, SULFATE ION, (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, ... (4 entities in total)
Functional Keywords	trimer of dimers, single tryptophan mutant, protein-inhibitor complex, transferase
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	3
Total formula weight	77789.43
Authors	Narczyk, M.,Bzowska, A. (deposition date: 2020-01-31, release date: 2021-02-10, Last modification date: 2024-01-24)
Primary citation	Narczyk, M.,Mioduszewski, L.,Oksiejuk, A.,Winiewska-Szajewska, M.,Wielgus-Kutrowska, B.,Gojdz, A.,Ciesla, J.,Bzowska, A. Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent. Sci Rep, 11:11144-11144, 2021 Cited by PubMed: 34045551 DOI: 10.1038/s41598-021-90472-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65000304482 Å)

Structure validation