8CJ0

E. coli NfsB-T41Q/N71S/F124T/M127V mutant bound to nicotinate

Summary for 8CJ0

• Entry DOI: 10.2210/pdb8cj0/pdb
• Descriptor: Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, ... (5 entities in total)
• Functional Keywords: nitroreductase mutant, complex, oxidoreductase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 48939.06

Authors

White, S.A.,Hyde, E.I.,Day, M.A. (deposition date: 2023-02-11, release date: 2023-04-19)

• Primary citation: Day, M.A.,Christofferson, A.J.,Anderson, J.L.R.,Vass, S.O.,Evans, A.,Searle, P.F.,White, S.A.,Hyde, E.I.; Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.; Int J Mol Sci, 24:-, 2023; PubMed: 36983061; DOI: 10.3390/ijms24065987

Experimental method

X-RAY DIFFRACTION (1.99 Å)