PDB: 2913 件ウェブページステータス検索Chemie searchBIRD

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8VZ9	Crystal structure of mouse MAIT M2A TCR-MR1-5-OP-RU complex 分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ... 著者 Ciacchi, L, Rossjohn, J, Awad, W. 登録日 2024-02-11 公開日 2024-04-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Mouse mucosal-associated invariant T cell receptor recognition of MR1 presenting the vitamin B metabolite, 5-(2-oxopropylideneamino)-6-d-ribitylaminouracil. J.Biol.Chem., 300, 2024
8WUL	Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) 分子名称: Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen, ... 著者 Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. 登録日 2023-10-20 公開日 2024-05-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
8WTE	Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) 分子名称: Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen (Fragment), ... 著者 Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. 登録日 2023-10-18 公開日 2024-05-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
8VSP	Cryo-EM structure of human invariant chain in complex with HLA-DQ 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, ... 著者 Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. 登録日 2024-01-24 公開日 2024-05-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
8WY0	T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A 分子名称: CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... 著者 Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. 登録日 2023-10-30 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
8WYI	T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC 分子名称: Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... 著者 Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. 登録日 2023-10-31 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
8VRW	Cryo-EM structure of human invariant chain in complex with HLA-DR15 分子名称: HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... 著者 Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. 登録日 2024-01-22 公開日 2024-05-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
8WXE	Vgamma5Vdelta1 EH TCR-CD3 complex 分子名称: CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ... 著者 Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. 登録日 2023-10-28 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
5N6B	Human Leukocyte Antigen Class I A02 Carrying LLWNPGMAV 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-2-microglobulin, ... 著者 Rizkallah, P.J, Cole, D.K, Fuller, A, Bulek, A.M, Bovay, A. 登録日 2017-02-14 公開日 2017-10-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 T cell receptor alpha variable 12-2 bias in the immunodominant response to Yellow fever virus. Eur. J. Immunol., 48, 2018
5NMK	HLA A02 presenting SLFNTIAVL 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. 登録日 2017-04-06 公開日 2017-11-15 最終更新日 2017-12-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
5MZM	Structure of H-2Db in complex with TEIPP APL Trh4 p3P 分子名称: Beta-2-microglobulin, Ceramide synthase 5 derived peptide Trh4 p3P, GLYCEROL, ... 著者 Hafstrand, I, Achour, A, Sandalova, T. 登録日 2017-02-01 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability. J. Immunol., 200, 2018
5MEN	Human Leukocyte Antigen A02 presenting ILAKFLHWL, in complex with cognate T-Cell Receptor 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Lloyd, A, Crowther, M, Cole, D.K, Sewell, A.K. 登録日 2016-11-16 公開日 2016-12-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structural Mechanism Underpinning Cross-reactivity of a CD8+ T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase. J. Biol. Chem., 292, 2017
5NME	868 TCR in complex with HLA A02 presenting SLYNTVATL 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. 登録日 2017-04-05 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
5NMH	HLA A02 presenting SLYNTIATL 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. 登録日 2017-04-05 公開日 2017-11-15 最終更新日 2017-12-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
5MP3	Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5 分子名称: ENSMUSG00000076577 protein, Igh protein, Microtubule-associated protein 著者 Skrabana, R, Novak, M, Cehlar, O, Kontsekova, E. 登録日 2016-12-15 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5 To be published
5LGK	Crystal structure of the human IgE-Fc bound to its B cell receptor derCD23 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ig epsilon chain C region, Low affinity immunoglobulin epsilon Fc receptor, ... 著者 Dhaliwal, B, Pang, M.O.Y, Sutton, B.J. 登録日 2016-07-07 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 IgE binds asymmetrically to its B cell receptor CD23. Sci Rep, 7, 2017
5NQ2	'Porcine (Sus scrofa) Major Histocompatibility Complex, class I, presenting IAYERMCNI 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CALCIUM ION, ... 著者 Rizkallah, P.J, Tungatt, K, Sewell, A.K. 登録日 2017-04-19 公開日 2018-04-25 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. Plos Pathog., 14, 2018
5N1Y	HLA-A02 carrying MVWGPDPLYV 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... 著者 Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. 登録日 2017-02-06 公開日 2017-02-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J. Clin. Invest., 126, 2016
8YC0	T cell receptor V delta2 V gamma9 in GDN 分子名称: CHOLESTEROL, T cell receptor delta variable 2,T cell receptor delta constant, T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... 著者 Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. 登録日 2024-02-17 公開日 2024-05-08 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.12 Å) 主引用文献 Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
8ESH	Structure of chimeric HLA-A*02:01 bound to CMV peptide 分子名称: Beta-2-microglobulin, CMV peptide, HLA-A*02:01 著者 Florio, T.J, Ani, O, Young, M.C, Mallik, L, Sgourakis, N.G. 登録日 2022-10-14 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Decoupling peptide binding from T cell receptor recognition with engineered chimeric MHC-I molecules. Front Immunol, 14, 2023
3HPJ	Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2009-06-04 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics. Mol.Immunol., 47, 2010
3I6K	Newly identified epitope from SARS-CoV membrane protein complexed with HLA-A*0201 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... 著者 Liu, J, Sun, Y, Qi, J, Chu, F, Wu, H, Gao, F, Li, T, Yan, J, Gao, G.F. 登録日 2009-07-07 公開日 2010-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The membrane protein of severe acute respiratory syndrome coronavirus acts as a dominant immunogen revealed by a clustering region of novel functionally and structurally defined cytotoxic T-lymphocyte epitopes J Infect Dis, 202, 2010
7YG3	Crystal structure of HLA-B*13:01 分子名称: ARG-GLN-ASP-ILE-LEU-ASP-LEU-TRP-ILE, Beta-2-microglobulin, MHC class I antigen 著者 Wang, H.S, Ouyang, S.Y. 登録日 2022-07-11 公開日 2023-07-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity. J.Biomed.Sci., 29, 2022
3I6L	Newly identified epitope N1 derived from SARS-CoV N protein complexed with HLA-A*2402 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... 著者 Liu, J.W. 登録日 2009-07-07 公開日 2010-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Novel immunodominant peptide presentation strategy: a featured HLA-A*2402-restricted cytotoxic T-lymphocyte epitope stabilized by intrachain hydrogen bonds from severe acute respiratory syndrome coronavirus nucleocapsid protein J.Virol., 84, 2010
8EUQ	Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... 著者 Kassardjian, A, Julien, J.-P. 登録日 2022-10-19 公開日 2023-04-19 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses. Cell Rep, 42, 2023

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