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2GET
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Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-I (LT)
分子名称: GLYCEROL, Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M.
登録日2006-03-20
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
Acta Crystallogr.,Sect.D, 62, 2006
2GEV
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Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-II (LT)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Pantothenate kinase, ...
著者Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M.
登録日2006-03-20
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
Acta Crystallogr.,Sect.D, 62, 2006
6MBA
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BU of 6mba by Molmil
Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONATE ION, ...
著者Yoder, J, Gabelli, S.B, Amzel, L.M.
登録日2018-08-29
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.
Nat Commun, 10, 2019
2GD7
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BU of 2gd7 by Molmil
The Structure of the Cyclin T-binding domain of Hexim1 reveals the molecular basis for regulation of transcription elongation
分子名称: HEXIM1 protein
著者Dames, S.A.
登録日2006-03-15
公開日2007-06-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2GVF
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HCV NS3-4A protease domain complexed with a macrocyclic ketoamide inhibitor, SCH419021
分子名称: (6R,8S,11S)-11-CYCLOHEXYL-N-(1-{[(2-{[(1S)-2-(DIMETHYLAMINO)-2-OXO-1-PHENYLETHYL]AMINO}-2-OXOETHYL)AMINO](OXO)ACETYL}BUTYL)-10,13-DIOXO-2,5-DIOXA-9,12-DIAZATRICYCLO[14.3.1.1~6,9~]HENICOSA-1(20),16,18-TRIENE-8-CARBOXAMIDE, Polyprotein, ZINC ION, ...
著者Arasappan, A, Njoroge, F.G, Chen, K.X, Venkatraman, S, Parekh, T.N, Gu, H, Pichardo, J, Butkiewicz, N, Prongay, A, Madison, V, Girijavallabhan, V.
登録日2006-05-02
公開日2007-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.
Bioorg.Med.Chem.Lett., 16, 2006
2RAC
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BU of 2rac by Molmil
AMICYANIN REDUCED, PH 7.7, 1.3 ANGSTROMS
分子名称: COPPER (I) ION, PROTEIN (AMICYANIN)
著者Cunane, L.M, Chen, Z.-W, Durley, R.C.E, Mathews, F.S.
登録日1998-10-02
公開日1998-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Molecular basis for interprotein complex-dependent effects on the redox properties of amicyanin.
Biochemistry, 37, 1998
2R7A
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BU of 2r7a by Molmil
Crystal Structure of a Periplasmic Heme Binding Protein from Shigella dysenteriae
分子名称: Bacterial heme binding protein, PROTOPORPHYRIN IX CONTAINING FE
著者Ho, W.W, Li, H, Poulos, T.L.
登録日2007-09-07
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Holo- and apo-bound structures of bacterial periplasmic heme-binding proteins.
J.Biol.Chem., 282, 2007
2RA3
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Human cationic trypsin complexed with bovine pancreatic trypsin inhibitor (BPTI)
分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
著者Salameh, M.A, Soares, A.S, Radisky, E.S.
登録日2007-09-14
公開日2007-12-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin.
J.Biol.Chem., 283, 2008
2R5Z
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BU of 2r5z by Molmil
Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene
分子名称: DNA (5'-D(*DAP*DCP*DTP*DCP*DTP*DAP*DAP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DGP*DGP*DCP*DTP*DG)-3'), DNA (5'-D(*DTP*DCP*DAP*DGP*DCP*DCP*DGP*DAP*DTP*DTP*DAP*DAP*DTP*DCP*DTP*DTP*DAP*DGP*DAP*DG)-3'), Homeobox protein extradenticle, ...
著者Aggarwal, A.K, Passner, J.M, Jain, R.
登録日2007-09-04
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Functional specificity of a Hox protein mediated by the recognition of minor groove structure
Cell(Cambridge,Mass.), 131, 2007
2RA8
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BU of 2ra8 by Molmil
Crystal structure of the Q64V53_BACFR protein from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR43
分子名称: Uncharacterized protein Q64V53_BACFR
著者Vorobiev, S.M, Abashidze, M, Seetharaman, J, Wang, D, Cunningham, K, Maglaqui, M, Owens, L, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2007-09-14
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the Q64V53_BACFR protein from Bacteroides fragilis.
To be Published
2RDY
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BU of 2rdy by Molmil
Crystal structure of a putative glycoside hydrolase family protein from Bacillus halodurans
分子名称: BH0842 protein
著者Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-09-25
公開日2007-10-09
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of a putative glycoside hydrolase family protein from Bacillus halodurans.
To be Published
2RJY
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BU of 2rjy by Molmil
Crystal structure of villin headpiece, P21 21 21 space group
分子名称: Villin-1
著者Meng, J, McKnight, C.J.
登録日2007-10-16
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of a pH-stabilized mutant of villin headpiece.
Biochemistry, 47, 2008
2R5K
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BU of 2r5k by Molmil
Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus type 11
分子名称: Major capsid protein L1
著者Bishop, B, Dasgupta, J, Chen, X.S.
登録日2007-09-03
公開日2008-05-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structures of four types of human papillomavirus L1 capsid proteins: understanding the specificity of neutralizing monoclonal antibodies.
J.Biol.Chem., 282, 2007
2R6M
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BU of 2r6m by Molmil
Crystal structure of rat CK2-beta subunit
分子名称: Casein kinase II subunit beta, ZINC ION
著者Shen, Y.
登録日2007-09-06
公開日2008-09-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of catalytic and regulatory subunits of rat protein kinase CK2
CHIN.SCI.BULL., 54, 2009
2TSS
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BU of 2tss by Molmil
TOXIC SHOCK SYNDROME TOXIN-1 FROM STAPHYLOCOCCUS AUREUS: ORTHORHOMBICC222(1) CRYSTAL FORM
分子名称: TOXIC SHOCK SYNDROME TOXIN-1
著者Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H.
登録日1996-12-04
公開日1997-12-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
2RG7
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BU of 2rg7 by Molmil
Apo- Crystal Structure of a Periplasmic Heme Binding Protein from Shigella dysenteriae
分子名称: Periplasmic HEME binding protein
著者Ho, W.W, Li, H.
登録日2007-10-02
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Holo- and apo-bound structures of bacterial periplasmic heme-binding proteins.
J.Biol.Chem., 282, 2007
2RLN
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BU of 2rln by Molmil
THERMODYNAMIC AND STRUCTURAL CONSEQUENCES OF CHANGING A SULPHUR ATOM TO A METHYLENE GROUP IN THE M13NLE MUTATION IN RIBONUCLEASE S
分子名称: RIBONUCLEASE, RIBONUCLEASE S (S-PROTEIN), SULFATE ION
著者Ratnaparkhi, G, Varadarajan, R.
登録日1994-07-11
公開日1994-11-01
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Thermodynamic and structural consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in ribonuclease-S.
Biochemistry, 33, 1994
2RDV
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BU of 2rdv by Molmil
RUBREDOXIN FROM DESULFOVIBRIO VULGARIS MIYAZAKI F, MONOCLINIC CRYSTAL FORM
分子名称: FE (III) ION, RUBREDOXIN
著者Higuchi, Y, Yasuoka, N.
登録日1998-10-07
公開日1999-05-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure determination of rubredoxin from Desulfovibrio vulgaris Miyazaki F in two crystal forms.
Acta Crystallogr.,Sect.D, 55, 1999
2RI9
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BU of 2ri9 by Molmil
Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Lobsanov, Y.D, Yoshida, T, Desmet, T, Nerinckx, W, Yip, P, Claeyssens, M, Herscovics, A, Howell, P.L.
登録日2007-10-10
公開日2008-03-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
2TCT
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THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE
分子名称: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, TETRACYCLINE REPRESSOR
著者Hinrichs, W, Kisker, C, Saenger, W.
登録日1995-03-02
公開日1996-04-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance.
J.Mol.Biol., 247, 1995
2TMK
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BU of 2tmk by Molmil
YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)
分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, SULFATE ION, THYMIDYLATE KINASE
著者Lavie, A, Schlichting, I.
登録日1997-06-12
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation.
Nat.Struct.Biol., 4, 1997
2TSR
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THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE, TOMUDEX
著者Sotelo-Mundo, R.R, Ciesla, J, Dzik, J.M, Rode, W, Maley, F, Maley, G, Hardy, L.W, Montfort, W.R.
登録日1998-06-19
公開日1999-02-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug.
Biochemistry, 38, 1999
2R83
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Crystal structure analysis of human synaptotagmin 1 C2A-C2B
分子名称: CHLORIDE ION, Synaptotagmin-1
著者Sutton, R.B, Fuson, K.L, Montes, M, Robert, J.J.
登録日2007-09-10
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association.
Biochemistry, 46, 2007
2RTL
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STREPTAVIDIN-2-IMINOBIOTIN-SULFATE COMPLEX, PH 2.50, SPACE GROUP I4122
分子名称: 2-IMINOBIOTIN, STREPTAVIDIN, SULFATE ION
著者Katz, B.A.
登録日1997-09-11
公開日1998-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Binding of biotin to streptavidin stabilizes intersubunit salt bridges between Asp61 and His87 at low pH.
J.Mol.Biol., 274, 1997
2TNF
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1.4 A RESOLUTION STRUCTURE OF MOUSE TUMOR NECROSIS FACTOR, TOWARDS MODULATION OF ITS SELECTIVITY AND TRIMERISATION
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ISOPROPYL ALCOHOL, PROTEIN (TUMOR NECROSIS FACTOR ALPHA)
著者Baeyens, K.J, De Bondt, H.L, Raeymaekers, A, Fiers, W, De Ranter, C.J.
登録日1998-10-12
公開日1999-10-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The structure of mouse tumour-necrosis factor at 1.4 A resolution: towards modulation of its selectivity and trimerization.
Acta Crystallogr.,Sect.D, 55, 1999

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